Quizlet - Microbiology - Clinical Patterns Flashcards
Tricky T’s: Typhoid fever
caused by bacterium Salmonella typhi.
Tricky T’s: Typhus
caused by bacteria Rickettsia prowazekii (epidemic), Rickettsia typhi (endemic), and Rickettsia tsutsugamushi (scrub typhus)
Tricky T’s: Chlamydia trachomatis
Bacteria, STD
Tricky T’s: Treponema
Spirochete; causes syphilis (T. pallidum) or yaws (T. pertenue)
Tricky T’s: Trichomonas vaginalis
Protozoan, STD.
Tricky T’s: Typanosoma
Protozoan, causes Chagas’ dz (T. cruzi) or African sleeping sickness.
Tricky T’s: Toxoplasma
protozoan, a TORCH infxn.
Tricky T’s: Trichinella spiralis
Nematode in undercooked meat.
Prions What are they? What dz’s do they cause? Normal vs. pathologic prions?
Infectious agents that do not contain RNA or DNA (consist only of proteins); encoded by cellular genes. Dz’s: Creutzfeldt-Jakob dz (CJD – rapidly progressive dementia), kuru, srapie (sheep), mad cow dz Associated w/ spongiform encephalopathy . Normal prions have alpha-helix conformation; pathologic prions (like CJD) are beta-pleated sheets. Pathologic conformation accumulates b/c it is resistant to proteinase digestion.
Dominant normal flora of the: Skin
Staphylococcus epidermis
Dominant normal flora of the: Nose
S. epidermis; colonized by S. aureus
Dominant normal flora of the: Oropharynx
Viridans group streptococci
Dominant normal flora of the: Dental plaque
Streptococcus mutans
Dominant normal flora of the: Colon
Bacteroides fragilis > E. coli
Dominant normal flora of the: Vagina
Lactobacillus, colonized by E. coli and GBS
Neonates and normal flora
Neonates delivered by cesarean section havve no flora, but are rapidly colonized after birth.
Food poisoning from: Vibrio parahemolyticus and V. vulnificus
Food: Contaminated seafood (V. vulnificus can also cause wound infxn from contact w/ contaminated water or shellfish)
Food poisoning from: Bacillus cereus
Food: reheated rice. (Food poisoning from reheated rice? Be Serious! [B. cereus])
Food poisoning from: S. aureus
Food: Meats, mayonnaise, custard (pre-formed toxin)
Food poisoning from: Clostridium perfringens
Food: reheated meat dishes
Food poisoning from: Clostridium botulinum
Food: improperly canned foods (bulging cans)
Food poisoning from: E. coli O157:H7
Food: Undercooked meat
Food poisoning from: Salmonella
Food: poultry, meat, and eggs.
What are two bacteria that cause a food poisoning that starts quickly and ends quickly?
S. aureus and B. cereus
Bugs that cause diarrhea: Campylobacter Type of diarrhea? Findings?
Bloody diarrhea. Comma- or S-shaped organisms; growth at 42C; Oxidase (+) [bugs that cause diarrhea: type of diarrhea and findings]
Bloody diarrhea. Comma- or S-shaped organisms; growth at 42C; Oxidase (+) [bugs that cause diarrhea: type of diarrhea and findings]
Bugs that cause diarrhea: Campylobacter
Bugs that cause diarrhea: Salmonella Type of diarrhea? Findings?
bloody diarrhea. Lactose (-); Flagellar motility [bugs that cause diarrhea: type of diarrhea and findings]
bloody diarrhea. Lactose (-); Flagellar motility [bugs that cause diarrhea: type of diarrhea and findings]
Bugs that cause diarrhea: Salmonella
Bugs that cause diarrhea: Shigella Type of diarrhea? Findings?
Bloody diarrhea Lactose (-) Very low ID50 Produces Shiga toxin [bugs that cause diarrhea: type of diarrhea and findings]
Bloody diarrhea Lactose (-) Very low ID50 Produces Shiga toxin [bugs that cause diarrhea: type of diarrhea and findings]
Bugs that cause diarrhea: Shigella
Bugs that cause diarrhea: Enterohemorrhagic E. coli (EHEC) Type of diarrhea? Findings?
Bloody diarrhea O157:H7 Can cause HUS Makes Shiga-like toxin [bugs that cause diarrhea: type of diarrhea and findings]
Bloody diarrhea O157:H7 Can cause HUS Makes Shiga-like toxin [bugs that cause diarrhea: type of diarrhea and findings]
Bugs that cause diarrhea: Enterohemorrhagic E. coli (EHEC)
Bugs that cause diarrhea: Enteroinvasive E. coli (EIEC) Type of diarrhea? Findings?
Bloody diarrhea. Invades colonic mucosa. [bugs that cause diarrhea: type of diarrhea and findings]
Bloody diarrhea. Invades colonic mucosa. [bugs that cause diarrhea: type of diarrhea and findings]
Bugs that cause diarrhea: Enteroinvasive E. coli (EIEC)
Bugs that cause diarrhea: Yersinia enterocolitica Type of diarrhea? Findings?
Bloody diarrhea Day-care outbreaks Pseudoappendicitis [bugs that cause diarrhea: type of diarrhea and findings]
Bloody diarrhea Day-care outbreaks Pseudoappendicitis [bugs that cause diarrhea: type of diarrhea and findings]
Bugs that cause diarrhea: Yersinia enterocolitica
Bugs that cause diarrhea: C. difficile Type of diarrhea? Findings?
Can cause both watery and bloody diarrhea. Pseudomembranous colitis. [bugs that cause diarrhea: type of diarrhea and findings]
Can cause both watery and bloody diarrhea. Pseudomembranous colitis. [bugs that cause diarrhea: type of diarrhea and findings]
Bugs that cause diarrhea: C. difficile
Bugs that cause diarrhea: Entamoeba histolytica Type of diarrhea? Findings?
Bloody diarrhea. Protozoan. [bugs that cause diarrhea: type of diarrhea and findings]
Bloody diarrhea. Protozoan. [bugs that cause diarrhea: type of diarrhea and findings]
Bugs that cause diarrhea: Entamoeba histolytica
Bugs that cause diarrhea: Enterotoxigenic E. coli (ETEC) Type of diarrhea? Findings?
Watery diarrhea. Traveler’s diarrhea Produces ST and LT toxins [bugs that cause diarrhea: type of diarrhea and findings]
Watery diarrhea. Traveler’s diarrhea Produces ST and LT toxins [bugs that cause diarrhea: type of diarrhea and findings]
Bugs that cause diarrhea: Enterotoxigenic E. coli (ETEC)
Bugs that cause diarrhea: Vibrio cholerae Type of diarrhea? Findings?
Watery diarrhea. Comma-shaped organisms Rice-water diarrhea. [bugs that cause diarrhea: type of diarrhea and findings]
Watery diarrhea. Comma-shaped organisms Rice-water diarrhea. [bugs that cause diarrhea: type of diarrhea and findings]
Bugs that cause diarrhea: Vibrio cholerae
Bugs that cause diarrhea: C. perfringens Type of diarrhea? Findings?
Watery diarrhea. Also causes gas gangrene. [bugs that cause diarrhea: type of diarrhea and findings]
Watery diarrhea. Also causes gas gangrene. [bugs that cause diarrhea: type of diarrhea and findings]
Bugs that cause diarrhea: C. perfringens
Bugs that cause diarrhea: Protozoa Type of diarrhea? Findings?
Watery diarrhea Giardia, Cryptosporidium (in immunocompromised) [bugs that cause diarrhea: type of diarrhea and findings]
Watery diarrhea Giardia, Cryptosporidium (in immunocompromised) [bugs that cause diarrhea: type of diarrhea and findings]
Bugs that cause diarrhea: Protozoa
Bugs that cause diarrhea: Viruses Type of diarrhea? Findings?
Watery diarrhea. Rotavirus, adenovirus, Norwalk virus (norovirus). [bugs that cause diarrhea: type of diarrhea and findings]
Common causes of pneumonia in neonates (< 4wks)
Group B streptococci E. coli
Common causes of pneumonia in children (4wks - 18yrs)
Viruses (R SV) M ycoplasma C hlamydia pneumoniae S treptococcus pneumoniae (R unts M ay C ough S putum)
Common causes of pneumonia in adults (18-40yrs)
Mycoplasma Chlamydia pneumoniae Streptococcus pneumoniae
Common causes of pneumonia in Adults (40-65yrs)
Streptococcus pneumoniae H. influenzae Anaerobes Viruses Mycoplasma
Common causes of pneumonia in the elderly (>65)
Streptococcus pneumoniae Viruses Anaerobes H. influenzae Gram (-) rods
Common causes of nosocomial (hospital-acquired) pneumonia
Staphylococcus Enteric Gram (-) rods
Common causes of pneumonia in the immunocompromised
Staphylococcus Enteric Gram (-) rods Fungi Viruses Pneumocystis jiroveci (w/ HIV)
Common cause of pneumonia w/ aspiration
Anaerobes
Common cause of pneumonia in alcoholics/IV drug users
Streptococcus pneumoniae Klebsiella Staphylococcus
Common causes of pneumonia in CF
Pseudomonas
Common causes of post-viral pneumonia
Staphylococcus H. influenzae
Common causes of atypical pneumonia
Mycoplasma Legionella Chlamydia
Common causes of meningitis in newborn (0-6 months
Group B streptococci E. coli Listeria
Common causes of meningitis in children (6mos - 6yrs)
Streptococcus pneumoniae Neisseria meningitidis Haemophilus influenzae type B Enteroviruses
Common causes of meningitis (6-60yrs)
N. miningitidis Enteroviruses S. pneumoniae HSV
Common causes of meningitis in 60+ year-olds
Streptococcus pneumoniae Gram (-) rods Listeria
Viral causes of meningitis
Enteroviruses (esp. coxsackievirus) HSV HIV West Nile virus VZV
Common causes of meningitis in HIV
Cryptococcus CMV Toxoplasmosis (brain abscess) JC virus (PML)
Incidence of H. influenzae meningitis?
Has decreased greatly w/ introduction of H. influenzae vaccine in last 10-15 years.
CSF findings in meningitis: Bacterial [Pressure? Cell type? Protein? Sugars?]
Increased pressure Increased PMNs Increased protein Decreased sugar
Increased pressure Increased PMNs Increased protein Decreased sugar [CSF findings in meningitis – what is the bug?]
Bacterial