Quizes Flashcards
Foods rich in fructooligosaccharides include all of the following except one.
Onions
Garlic
Yacon tubers
Black beans
Black beans
Which of the following probiotic products has clinical trial evidence of efficacy for the treatment of infantile colic?
Select one:
Culturelle Kids Probiotic
Natural Factors Children’s Multi Probiotic
Bio-Kult Infantis
Klaire Labs Ther-Biotic Children’s Chewable
Bio-Kult Infantis
All of the following are prebiotics except one. Choose the exception:
Select one: fructooligosaccharides lactulose larch arabinogalactans lactitol galactooligosaccharides
larch arabinogalactans
The prebiotics with the current best research profile for improving skin health (levels of wrinkles and hydration) are?
Select one or more: Lactulose and Arabinogalactans Lactulose and GOS GOS and FOS Lactulose and FOS
Lactulose and GOS
What differentiates prebiotics from colonic foods?
Select one:
a. Only colonic foods are fermented to produce short-chain fatty acids
b. Prebiotics are only utilized by a limited number of beneficial bacteria in the human GIT
c. Prebiotics have to be naturally-occurring, whereas colonic foods do not
d. Nothing differentiates them – they are different terms for the same thing
E. Only prebiotics are fermented to produce short-chain fatty acids
b. Prebiotics are only utilized by a limited number of beneficial bacteria in the human GIT
Probiotic characteristics are strain dependent. This means:
Select one:
a. Desirable characteristics cannot be extrapolated across the species level
b. Strains within the same species may have differing therapeutic qualities
c. One cannot generalize research results conducted on one probiotic strain to another one, even if it is within the same species
d. All of the above
d. All of the above
Which of the following is not a common side effect from prebiotic administration?
Select one:
a. Flatulence
b. Abdominal distension
c. Sore joints
d. Abdominal bloating
e. Abdominal pain
c. Sore joints
What is the best rationale to base your prescribing of a particular probiotic supplement on?
Select one:
a. Your clinical experience
b. Your colleagues’ clinical experience
c. Choose the supplement with the highest CFU (colony forming units)
d. Clinical trial level evidence of efficacy
e. Claims made in a manufacturers’ brochure
d. Clinical trial level evidence of efficacy
Based on clinical trial data, the probiotic strains of choice in bacterial vaginosis are:
Select one:
a. Lactobacillus rhamnosus GG and Bifidobacterium lactis Bb12
b. Lactobacillus rhamnosus GR-1 and Lactobacillus reuteri RC-14
c. Lactobacillus plantarum Lp-115 and Lactobacillus rhamnosus CUL-63
d. Lactobacillus rhamnosus CUL-63 and Lactobacillus fermentum CUL-67
b. Lactobacillus rhamnosus GR-1 and Lactobacillus reuteri RC-14
Based on the most recent research, probiotics can be used to treat:
Select one:
a. Endometriosis
b. Post-partum obesity
c. Mastitis
d. All of the above
d. All of the above
Which of the following is not a probiotic myth?
Select one:
a. Never take probiotics alongside antibiotics as it is a waste of money
b. Probiotics are best taken on an empty stomach
c. Probiotics are best taken with larger, more dense meals to enhance survival through the upper GIT
d. A good probiotic strain will permanently colonize the human GIT after consumption
e. Probiotic supplements are superior to probiotic foods as therapeutic tools
c. Probiotics are best taken with larger, more dense meals to enhance survival through the upper GIT
A prebiotic must have all the following characteristics except one. The exception is:
Select one:
a. ingestion of the substance alters the colonic microflora ecosystem towards a healthier composition
b. the substance must be neither catabolised nor absorbed in the stomach or small intestine
c. ingestion results in changes that improve the health of the host
d. the substance must be naturally occurring
e. the substance must be a selective substrate only utilised by a limited number of beneficial bacteria
d. the substance must be naturally occurring
What is the minimum therapeutic dose of a probiotic strain?
Select one:
a. It differs per strain, but it is a prudent to prescribe a minimum of 1 billion (10^9) colony forming units (CFU) of each strain
b. It differs per strain, but it is a prudent to prescribe a minimum of 100 million CFU (10^8) of each strain
c. 10 billion (10^10) CFU
d. 100,000 (10^6) CFU
a. It differs per strain, but it is a prudent to prescribe a minimum of 1 billion (10^9) colony forming units (CFU) of each strain
Which of the following disease states has been associated with gastrointestinal dysbiosis?
Select one or more:
a. Obesity and Type 2 Diabetes
b. Chronic Fatigue Syndrome and Autism
c. Depression and Anxiety
d. All of the above
e. None of the above
d. All of the above
Foods rich in galactooligosaccharides include all of the following except one. Choose the exception.
Select one or more:
a.
Borlotti beans
b.
Buckwheat
c.
Split peas
d.
Whole wheat
b.
Buckwheat
What is the prebiotic of choice to prevent Traveler’s diarrhea?
Select one:
a.
Fructooligosaccharides
b.
Galactooligosaccharides
c.
Larch arabinogalactans
d.
Raffinose
b.
Galactooligosaccharides
The probiotic strain Lactobacillus reuteri BioGaia is found in which commercially-available probiotic preparation in the USA?
Select one:
a.
Bioceuticals UltraBiotic 45
b.
Natren Healthy Trinity
c.
Gerber Soother Colic Drops
d.
Standard Process ProSynbiotic
c.
Gerber Soother Colic Drops
Which of the following is not a mechanism by which probiotics work:
Select one:
a.
Conversion of excess intestinal gases to water
b.
Competition for space and nutrients with potential pathogens
c.
Production of selectively-acting anti-microbial substances
d.
Via interaction with immune cells along the GIT
e.
Via production of beneficial compounds in the GIT (e.g., polyamines)
a.
Conversion of excess intestinal gases to water
All of the following are desirable probiotic characteristics except one; choose the exception:
Select one:
a.
Human origin
b.
Documented clinical safety
c.
Adherence to the intestinal mucosa
d.
Ability to colonize the human gastrointestinal tract (albeit only temporarily)
e.
Antagonism against lactobacilli and bifidobacteria
e.
Antagonism against lactobacilli and bifidobacteria
A species commonly used in probiotic supplements is:
Select one:
a.
Klebsiella pneumoniae
b.
Campylobacter jejuni
c.
Bacillus anthracis
d.
Saccharomyces cerevisiae
d.
Saccharomyces cerevisiae
Hydrogen sulfide gas is produced by which colonic bacterial species:
Select one:
a.
Bifidobacterium spp. and Lactobacillus spp.
b.
Desulfovibrio spp. and Bacteroides spp.
c.
Bifidobacterium spp. and Desulfomaculum spp.
d.
Desulfovibrio spp. and Desulfomaculum spp.
d.
Desulfovibrio spp. and Desulfomaculum spp.
Which of the following probiotic strains increase your endogenous populations of bifidobacteria when consumed:
Select one:
a.
Lactobacillus casei Shirota
b.
Lactobacillus acidophilus NCFM
c.
Lactobacillus rhamnosus GG
d.
All of the above
e.
None of the above
d.
All of the above
Which of the following is not a physiological activity of short chain fatty acids:
Select one:
a.
Trophic effects on the small intestine
b.
Improved colonic epithelial barrier function
c.
Improved serum vitamin B12 levels
d.
Improved mineral absorption
e.
Improved laxation
c.
Improved serum vitamin B12 levels
A high milk-fat diet encouraged the growth of what microorganism?
Select one:
a.
Lactobacillus acidophilus
b.
Bifidobacterium lactis
c.
Clostridiodes difficile
d.
Bacteroides fragilis
e.
Bilophila wadsworthia
e.
Bilophila wadsworthia
Which short chain fatty acid directly suppresses the growth of the main methane-producing bacterial species in the gastrointestinal tract (Methanobrevibacter smithii)?
Select one or more:
a.
Acetate
b.
Lactate
c.
Propionate
d.
Butyrate
d.
Butyrate
The three main short chain fatty acids produced in the colon are:
Select one:
a.
Hydrochloric, acetate, and butyrate
b.
Acetate, butyrate and lactate
c.
Propionate, butyrate and acetate
d.
Lactate, propionate and isovalerate
e.
Isovalerate, acetate and butyrate
c.
Propionate, butyrate and acetate
A pathobiont is defined as:
Select one or more:
a.
A healthy balanced ecosystem
b.
A commensal microorganism that is able to promote pathology only when specific genetic or environmental conditions are altered in the host
c.
A unit of biological organization composed to a host and its microbiota
d.
A relationship benefitting both parties
b.
A commensal microorganism that is able to promote pathology only when specific genetic or environmental conditions are altered in the host
Which of the following conditions is not associated with intestinal dysbiosis?
Select one:
a.
Obesity
b.
Irritable bowel syndrome
c.
Rheumatoid arthritis
d.
Atopic eczema
e.
Functional dyspepsia
e.
Functional dyspepsia
Which of the following is not a byproduct of intestinal putrefaction?
Select one:
a.
Short chain fatty acids
b.
hydrogen peroxide
c.
Phenols
d.
Indoles
e.
Ammonia
b.
hydrogen peroxide
The disappearing microbiota hypothesis states:
Select one:
a.
That alterations in human macroecology have progressively affected the composition of our indigenous microbiota, which in turn has affected human physiology and, ultimately, increased the risk of allergic and metabolic diseases
b.
That the increased rates of modern allergic and metabolic diseases has arisen due to changes in our genetics
c.
That the increased rates of modern allergic and metabolic diseases has arisen due to global warming.
d.
All of the above
e.
None of the above
a.
That alterations in human macroecology have progressively affected the composition of our indigenous microbiota, which in turn has affected human physiology and, ultimately, increased the risk of allergic and metabolic diseases
Which if the following bacterial genera are capable of producing butyrate? Choose the most correct answer.
Select one or more:
a.
Anaerostipes, Bifidobacterium, and Lactobacillus
b.
Anaerotruncus, Faecalibacterium, Roseburia
c.
Atopobium, Faecalibacterium, Enterococcus
d.
Escherichia, Bacteroides, Peptococcus
b.
Anaerotruncus, Faecalibacterium, Roseburia
The potential for an antimicrobial agent to influence the gut microflora is related to its:
Select one:
a.
Pharmacokinetics
b.
Spectrum of activity
c.
Length of administration
d.
All of the above
e.
None of the above
d.
All of the above
Putrefaction is the process by which:
Select one:
a.
Oligosaccharides are fermented
b.
Non-starch polysaccharides are fermented
c.
Protein is fermented
d.
Resistant starch is fermented
c.
Protein is fermented
Which of the following disease states has been associated with gastrointestinal dysbiosis?
Select one or more:
a.
Obesity and Type 2 Diabetes
b.
Chronic Fatigue Syndrome and Autism
c.
Depression and Anxiety
d.
All of the above
e.
None of the above
d.
All of the above
Causes of dysbiosis include:
Select one:
a.
Antibiotics
b.
Stress
c.
Birth via Caesarean section
d.
All of the above
d.
All of the above
The main cause of gastrooesophageal reflux is:
Select one:
a.
High gastric acid output
b.
Cigarette smoking
c.
Low gastric acid output
d.
Lower esophageal sphincter incompetence
d.
Lower esophageal sphincter incompetence
Melatonin helps in GERD by:
Select one:
a.
Inhibiting gastric acid output
b.
Inhibiting nitric oxide biosynthesis; thereby reducing the rate of transient relaxations in the LES
c.
Strengthening the LES
d.
All of the above
e.
None of the above
d.
All of the above
In human clinical trials, which agent(s) appears to be the most effective in eradicating H. pylori when used without antibiotics?
Select one:
a. Mastic gum (Pistacia lentiscus var Chia)
b. Rhubarb root (Rheum emodi)
c. Black seed (Nigella sativa)
d.
Vitamin C
e.
Vitamin E and C
c. Black seed (Nigella sativa)
All of the following agents can be used to improve the efficacy of antibiotics in eradicating H. pylori except:
Select one:
a.
Vitamin C and vitamin E
b.
Lactose
c.
Vitamin C
d.
Zinc carnosine
e.
Lactobacillus acidophilus La5 and Bifidobacterium lactis Bb12
b.
Lactose
According to human clinical trials, which agent appears to have the greatest effect in speeding the healing of peptic ulcers?
Select one:
a.
Zinc carnosine
b.
Cabbage juice
c.
Melatonin
d.
Mastic gum
b.
Cabbage juice