Quiz Units C & D Flashcards
Is conception a single process?
No. It is a sequence of events which includes: Gamete formation (egg and sperm), Ovulation, Fertilization and Implantation.
Where is the egg released from?
The ruptured ovarian follicle
What increases the motility of the uterine tubes so that cilia can capture the egg and propel it towards the uterine cavity?
Estrogen
When is the fertilized egg viable?
24 hours after ovulation
Can ova move on their own?
No
Normal ejaculation produces about 1 _____ of semen, which contains about _____ million - _____ million sperm cells.
1 tsp. 200-500 million
How long does it take them to get to the uterus, and how long are they viable?
4-6 hours. 2-3 days.
What helps the sperm penetrate the protective layers of the ovum?
Enzymes produced by its acrosomal cap
Where does fertilization occur?
In the Ampulla, which is the outer 3rd of the uterine tube.
When does fertilization occur?
When there is a Zona reaction, which is when the sperm is enclosed within the outer membrane, and it becomes impenetrable to other sperm.
When is conception complete?
When the head of the sperm enlarges to become the male pronucleus and the tail degenerates. The nuclei fuse and the chromosomes combine, restoring the diploid number (46)
When does implantation (nadation) occur?
7-10 days
What is the endometrium called after implantation?
The decidua
In the 3-4 days the Zygote takes to travel the uterine tube cleavage occurs. How much does it grow in size, and what is it then called?
It does not increase in size at all, and the 16 cell ball is called a morula.
What are the 3 stages of intrauterine development called?
Ovum/preembryonic (1st 14 days), embryo (day 15-8wks), and fetus.
When do the primary germ layers differentiate? Name them.
During the embryo stage. Endoderm, mesoderm, and ectoderm
What does the ectoderm differentiate into?
Epidermis, glands, nails, hair, nervous system, lens of the eye, tooth enamel, and the floor of the amniotic cavity
What does the mesoderm differentiate into?
Bones, teeth, muscles, dermis, connective tissue, cardiovascular system, spleen, and urogenital system
What does the endoderm differentiate into?
Epithelium lining the respiratory tract, digestive tract, and glandular cells of associated organs
What is Nagele’s rule?
A way to approximate the due date. From the 1st day of LMP, add 9 months and 7 days, or subtract 3 months and add 7 days and 1 yr
What’s the difference between the G/P system and GTPAL?
G/P is just # of times pregnant/# of times delivered & GTPAL divides parity into Term and Preterm and adds Abortions and # Living
What are some s/s of Turner’s syndrome?
Thick, webbed neck, wide set nipples, cardiac anomalies, recessed chin, learning disabilities, low set ears
What is Turner’s syndrome?
A chromosomal abnormality that only affects females.
What are the s/s of Kleinfelter’s syndrome?
Small testes, gynomastia, long legs, minimal body and facial hair, infertile
What causes Down’s syndrome?
An abnormality in the # of chromosomes.
Describe multifactorial transmission defects.
Most common type, combination of environmental and genetic, causes cleft palate, neural tube defects, congenital heart disease, pyloric stenosis
What is a classic sign that a neonate might have pyloric stenosis?
Projectile vomiting
What is a “congenital” condition, and what besides genetic defects can cause them?
Congenital means present at birth. They can be caused by teratogens, like chemicals, drugs, radiation, infections, and maternal disease like PKU and DM
What is the best preventative for LBW babies and preterm delivery?
Good nutrition before and during pregnancy
What is the difference between mitosis and meiosis?
Mitosis = cell divides and makes 2 identical cells. Meiosis = cell divides and each has only 23 chromosomes (sex cells)
How long is pregnancy?
10 lunar months/9 calendar months or 280 days
What 2 layers surround the ovum?
The Zona Pellucida (inner) and the corona radiate
What happens if an egg is not fertilized?
It disintegrates and is reabsorbed
When is the egg very susceptible to teratogens?
During the preembryonic stage
What are the 2 fetal membranes called?
The chorion (inside) and the amnion (outside)
If baby has too little amniotic fluid (< 300 mL) it is called _____?
Oligohydramnios
If baby has too much amniotic fluid (> 2 L) it is called _____?
Polyhydramnios
What does oligohydramnios often signal?
Renal insufficiency
What does polyhydramnios signal?
GI problems, malformations
What is amniotic fluid derived from?
Maternal blood
How much fluid is present at full term?
About 800-1200 mL
How many arteries and veins are in the umbilical cord? How big is it?
2 arteries and 1 vein. About the size of an adult finger
What fluid keeps the vessels within the umbilical cord from compressing?
Wharton’s jelly
What hormones are produced during pregnancy?
Hcg, HPL, estrogen, progesterone
When is Hcg produced?
It starts 8 days after conception. It is at its max at 50-70 days, then decreases
What is HPL?
Human Placental Lactogen
What does HPL do?
Like growth hormone. Stimulates maternal metabolism to provide for placenta
When is fetal circulation in place and the beating of the heart?
By day 17
What is the functional unit of utero placental circulation and how many are there?
Cotyledons. 15-20
When is a fetus considered viable?
20 wks or at least 500 grams
When is a lost fetus considered an abortion?
Less than 20 wks
What is considered a term baby?
37-40 wks
What is considered a preterm baby?
20-36 wks
If a mom is pregnant for the first time with triplets, she is considered gravida _____.
- Gravida is the # of pregnancies, regardless of the # of babies involved.
Define parity.
The # of pregnancies that reach 20 wks
What is Couvade’s syndrome?
When the father feels symptoms of pregnancy
What are some presumptive indicators of pregnancy?
Missed period, positive home test, Amenorrhea, N/V, fatigue, morning sickness, urinary frequency, quickening (18-20 wks)
What are some probable s/s of pregnancy?
Uterine enlargement, Braxton Hicks ( painless contractions), Darkening of pigmentation, Chadwik’s sign (discoloration of vaginal mucosa), Hagar’s sign (lower part of uterus softens), Ballottement (feel their fetus rebound), positive pregnancy test (Hcg), uterine souffle (blood rushing thru placenta)
What are the positive s/s of pregnancy?
Examiner feels fetal movement, FHR, visualization (by ultrasound)
What are some test run immediately when pregnancy is determined?
V/S, fetal heart tones, urine protein
What is the proper Hgb for a pregnant woman?
11-12 (normal is 12-26). <11 is anemic. It drops b/c of dilution due to the increase in blood volume
What happens to RBCs during pregnancy?
Normally they are 3.8-5.1, but when pregnant they rise to 4.6-6.5
What happens to WBCs during pregnancy?
They rise from a normal level of 5-10 to 15-25
How many extra Kcal does a pregnant woman need?
300 per day
What does oxytocin do during pregnancy?
Contracts the uterus
What does prolactin do during pregnancy?
Milk production
Where is estrogen produced from during pregnancy?
Ovaries and placenta
What is the function of estrogen during pregnancy?
Stretch marks, sodium and water retention (dependent edema), enlarge uterus/breasts/cervix, vascular changes
What is the function of progesterone during pregnancy?
Maintains endometrium, inhibits contractility, promotes breast duct development
What is the function of Hcg during pregnancy?
Stimulates estrogen
What is the function of HPL during pregnancy?
Increase glucose, which stimulates the pancreas and liver and increases pigmentation
What is the function of Relaxin during pregnancy?
Relaxes and stretches connective tissue, including the cervix
What is the definition of a high risk pregnancy?
A pregnancy in which the life or health of the fetus or mother is jeopardized by a disorder unique to the pregnancy
What helps prevent infant and maternal morbidity?
Timely interventions
What is a TORCH screening?
Toxoplasmosis, other (hepatitis), rubella, cytomegalia virus, herpes. These cause 2% of the major malformations during pregnancy
When is a MMR given?
30 days after delivery, because it is a live virus
What is the U.S. infant mortality rate, and what is Healthy People 2020’s goal?
Currently it is 7.8/100,000 live births (23rd among industrialized nations). 3.3 is the goal.
What are considered “high risk” categories?
Multiple births, Rh incompatibility, 3 pregnancies in 2 years, smoking (LBW & early ROM), drugs <11, LBW (higher mortality), alcohol (FAS, learning disability, wide set eyes, nose flattened)