quiz-proteins and enzymes Flashcards
enzyme
catalytic protein
catalyst
-a chemical agent that speeds up a reaction without being consumed by the reaction
substrate
small part that goes into enzyme
active site
3d cavity of the enzyme with specific chemical properties that enable it to accommodate the substrate
cofactors
broad term, the nonprotein part of an enzyme necessary for its catalytic function
coenzymes
a nonprotein organic molecule, frequently a B vitamin, that acts as a cofactor
activation and inhibition
competitive and non-competitive
ex: toxins, poisons, pesticides, and antibiotics
factors that influence enzyme activity
-temperature
-pH
-chemical
lock and key model
- a model explaining the specificity of enzyme action by comparing the active site to a lock and the substrate to a key
-not dynamic enough to be completely accurate
induced fit model
-a model explaining the specificity of enzyme action by comparing the active site to a glove and the substrate to a hand
-can explain non-competitive inhibition
activation energy
-Ea
transition state
reaction equilibrium and free energy change
feedback control
-enzyme regulation process in which formation of a product inhibits an earlier reaction in the sequence
proenzymes of zymogens
-an inactive protein that becomes an active enzyme after undergoing a chemical change
allosteric enzymes
-enzyme regulation that takes place at another part of the enzyme
-modifies the enzyme’s ability
inhibitor
compound that binds to an enzyme and lowers its activity
competitive inhibition
-competetive inhibitors actually enters the active sight, preventing the substrate from entering
non competitive inhibition
- inhibitor binds itself to a site other than the active site (allosterism), thereby changing the conformation of the active site
inactive enzymes
-manufactured by the body in an inactive form, to make active a small part of polypeptide chain must be removed
feedback inhibition
-the end product of a metabolic pathway shuts down the pathway
-prevents a cell from wasting chemical resources