Quiz II (1-7) Flashcards

1
Q

Given a network with two species, A and B, and four reactions:

R1: A+ B -> 2B
R2: B -> A
R3: A ->
R4: -> A

Which of the following is the stoichiometric matrix N?

[
-1 1 -1 1
1 -1 0 0
]

[
-1 1 -1 1
1 0 0 0
2 0 0 0
]

[
-1 1 0 0
2 -1 -1 1
]

[
1 1 -1 1
1 -1 0 0
]

A

[
-1 1 -1 1
1 -1 0 0
]

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2
Q

Given a network with two species, A and B, and four reactions:

R1: A+ B -> 2B
R2: B -> A
R3: A ->
R4: -> A

Which of the following is a steady state flux distribution?

[1 1 1 1]T

[2 1 2 1]T

[1 1 3 3]T

[1 1 2 1]T

A

[1 1 1 1]T

[1 1 3 3]T

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3
Q

Given a network with two species, A and B, and four reactions:

R1: A+ B -> 2B
R2: B -> A
R3: A ->
R4: -> A

Which of the following pairs are fully coupled?

R3 and R4
R1 and R2
R2 and R3
R1 and R3

A

R3 and R4
R1 and R2

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4
Q

Given a network with two species, A and B, and four reactions:

R1: A+ B -> 2B
R2: B -> A
R3: A ->
R4: -> A

If the upper-bound of all fluxes is 1000, maximizing the steady-state flux through reaction R2 implies…

The steady-state flux through reaction R4 is 1000

The steady state flux through reaction R3 is 1000

The steady-state flux through reaction R1 is 1000

The steady-state flux through reaction R1 is 0

A

The steady-state flux through reaction R1 is 1000

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5
Q

Given a network with two species, A and B, and four reactions:

R1: A+ B -> 2B
R2: B -> A
R3: A ->
R4: -> A

If the upper-bound to all fluxes is 500, maximizing the steady-state flux through reaction R2 implies that…

The range of reaction R2 at the respective optimum is [0, 500]

The range of reaction R3 at the respective optimum is [-500, 500]

The range of reaction R1 at the respective optimum is [-500, 500]

The range of reaction R4 at the respective optimum is [0, 500]

A

The range of reaction R4 at the respective optimum is [0, 500]

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6
Q

Given a network with two species, A and B, and four reactions:

R1: A+ B -> 2B
R2: B -> A
R3: A ->
R4: -> A

The network does not contain any exchange reactions - true or false?

A

FALSE

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7
Q

Given a network with two species, A and B, and four reactions:

R1: A+ B -> 2B
R2: B -> A
R3: A ->
R4: -> A

The network contains directionally coupled reactions - true or false?

A

FALSE

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8
Q

Given a network with two species, A and B, and four reactions:

R1: A+ B -> 2B
R2: B -> A
R3: A ->
R4: -> A

The rank of the stoichiometric matrix is __ .

(Explain.)

A

1

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9
Q

Protein complexes in a metabolic network are described by ….

A

Gene-Protein-Reaction rules.

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10
Q

True or false:

The linear program formulating the Flux Balance Analysis (with non-empty feasible space) is guaranteed to have a single flux distribution realizing the optimum z = max(vbio)

A

TRUE

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