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Sepsis week > Quiz > Flashcards

Quiz Flashcards

1
Q

What are the 4C antibiotics that have increased risk of C.diff infection

A

Co-amoxiclav
Cephalosporins
Clindamycin
Ciprofloxacin (Quinolones)

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2
Q

Which antibiotic causes photosensitivity as a side effect

A

doxycycline

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3
Q

Which group of antibiotics lower the epileptic threshold

A

Quinolones

ciprofloxacin, moxifloxacin, ofloxacin

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4
Q

Which quinolone is better for respiratory infection: ciprfloxacin or levofloxacin

A

Levofloxacin

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5
Q

What cover does clarithromycin provide in CAP

A

it covers atypical organisms

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6
Q

What antibiotic covers strep pneumoniae

A

amoxicillin

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7
Q

Which antibiotic is not absorbed systemically

A

Vancomycin when given PO

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8
Q

What are the side effects of quinolones

A

tendonitis
ruptured aortic aneurysms
seizures/psychiatric side effects
C.diff infection

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9
Q

What is absorbed better, PO or IV quinolones

A

PO

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10
Q

What is the alternative antibiotic to gentamicin

A

aztreonam

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11
Q

Name a gram positive bacilli

A

Listeria monocytogenes

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12
Q

Which antibiotics can cause deranged LFTs

A

Co-amoxiclav

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13
Q

What group of people are associated with Salmonella infections

A

HIV

Sickle cell anaemia

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14
Q

Tetracyclines can be given to all age groups, true or false

A

False, they should not be given to <12 because of permanent teeth staining

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15
Q

Which antibiotic should never be used as a monotherapy

A

Rifampicin - bacteria can rapidly acquire resistance to it

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16
Q

Which antibiotic does not cover Staph. A

A

penicillin

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17
Q

In which condition are Koplik spots found

A

Measles

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18
Q

Which bug causes “walking” pneumonia

A

Mycoplasma pneumoniae

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19
Q

Which disease is transmitted via air when you sneeze

A

Measles

20
Q

Which bacteria can be contaminants in cultures

A

Staph. epidermidis

Diphtheroids

21
Q

If you have an allergy to penicillins, what part of the chemical are you allergic to

A

Beta lactam ring

22
Q

name the Beta lactam antibiotics

A 
penicillin, amoxicillin, flucloxacillin...
Co-amoxiclav 
cephalosporins 
pipercillin-tazobactam 
carepenems
23
Q

Does penicillin cover streptococcus

A

yes, and nesseria meningitides and some anaerobes

24
Q

What does amoxicillin cover

A

enterococcus faecalis, strep, anaerobes and HiB

25
Q

Is co-amoxiclav broad spectrum

A

Yes, it covers Gm+, Gm- and anaerobes
It also increases risk of C.diff infections
It does not cover MRSA or coag-ve staph, pseudomonas, ESBLs or legionella

26
Q

Flucloxacillin is a broad spectrum antibiotic, true or false

A

False, it only covers staph and strep

27
Q

Give properties of clindamycin

A

It increases risk of C.diff infection
It has anti toxin properties
it covers MRSA, MSSA, strep and anaerobes

28
Q

What do the macrolides cover

A

atypical organisms in pneumonia

29
Q

Which antibiotics cover anaerobes

A

Metronidazole and clindamycin

30
Q

What does vancomycin cover

A

Gram +ves MRSA, MSSA, coag-ve staph, enterococci, strep, Clostridium

31
Q

Is co-trimoxazole a narrow spectrum antibiotic

A

No, it covers Gm+, Gm- and anaerobes

32
Q

What is gentamicin effective against

A

Gram negatives

Some synergistic effects against gram positives

33
Q

What does ciprofloxacin work against

A

Gram negatives

34
Q

What are the last resort antibiotics

A

Cerbepenems

35
Q

What are risk factors for getting a C.diff infection

A

Elderly, prolonged hospital stay, prophylactic antibiotics, PPIs, immunocompromised

36
Q

What is the treatment for non-severe C.diff

A

metronidazole PO

37
Q

What is the treatment for severe C.diff

A

PO vancomycin

38
Q

What makes gram negatives different from gram positives

A

They have a thinner peptidoglycan wall and an additional outer membrane
they are harder to treat

39
Q

Does gentamicin have any anaerobic cover

A

No

40
Q

What classifies as a hospital acquired pneumonia

A

Stay in hospital >48 hours

41
Q

What covers Haemophilus influenzae

A

amoxicillin and doxycycline

42
Q

What are the atypical organisms in pneumonia and their treatment

A

Mycoplasma pneumoniae - macrolide
Coxiella - Q fever - macrolide
Chlamydophila psittici - macrolide
Legionella - LEVOFLOXACIN

43
Q

What is used to treat pseudomonas

A

ciprofloxacin

44
Q

When a bug is an extended spectrum beta lactamase, which antibiotics is it resistant to

A

Penicillins, cephalosporins and aztreonam

45
Q

Which has better PO absorption, penicillin or amoxicillin

A

Amoxicillin

Sepsis week (3 decks)

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