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Top 300 Drugs > Quiz 6 > Flashcards

Quiz 6 Flashcards

1
Q

Atenelol

A

Tenormin

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2
Q

Lovastatin

A

Altoprev

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3
Q

Lisinopril

A

Prinivil, Zestril

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4
Q

Losartan

A

Cozaar

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5
Q

Amlodipine

A

Norvasc

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6
Q

Hydrochlorothiazide

A

various

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7
Q

Candesartan

A

Atacand

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8
Q

Indications: Angina pectoris, HTN, AMI

A

Atenolol

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9
Q

Indications: Coronary arteriosclerosis; hypercholesteremia, primary and fixed; familial hypercholesteremia, heterozyogous

A

Lovastatin

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10
Q

Indications: st-segment elevation, MI; HFrEF; HTN

A

Lisinopril

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11
Q

Indications: HTN, Reduced risk of cerebrovascular accident, diabetic nephropathy

A

Losartan

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12
Q

Indications: HTN; stable and variant angina

A

Amlodipine

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13
Q

Indications: edema, HTN

A

Hydrochlorothiazide

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14
Q

Indications: HF, HTN

A

Candesartan

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15
Q

Interactions: NSAIDs, amiodarone, dronedarone, antidiabetics, CCBs, quinidine, clonidine

A

Atenolol

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16
Q

Interactions: CYP3A4/5 inhibitors and inducers, fibrates, niacin

A

Lovastatin

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17
Q

Interactions: ARBs, K-sparing diuretics, azathioprine, cyclosporine diuretics, NSAIDs, K-supplements, salt subs, sacubitril

A

Lisinopril

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18
Q

Interactions: ACEIs, Diuretics, Aliskiren, CYP2CP and CYP3A4/5 inhibitors and inducers, K supplements, salt subs, NSAIDs

A

Losartan

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19
Q

Interactions: CYP3A4/5 inhibitors and inducers, NSAIDs

A

Amlodipine

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20
Q

Interactions: ace/arbs, antiarrhythmic agents, digoxin, antidiabetic meds, calcium supplements, carbamazepine, NSAIDs, Topiramate, lithium, dofetilide

A

Hydrochlorothiazide

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21
Q

Interactions: Aldosterone antagonists, ACE, K supplements, NSAIDs, Diuretics

A

Candesartan

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22
Q

Common AR: hypotension

A

Candesartan

23
Q

Common AR: hypotension, dizziness, headache

A

HCTZ

24
Q

Common AR: Peripheral Edema, PE

A

Amlodipine

25
Q

Common AR: headache

A

Losartan

26
Q

Common AR: n/a

A

Lisinopril and Lovastatin

27
Q

Common AR: Bradyarrhythmia, cold extremities, dizziness, fatigue, hypotension, depression

A

Atenolol

28
Q

RbS: HF, PE

A

Atenolol

29
Q

RbS: Rhabdomyolysis, hepatotoxicity, inc. risk of diabetes

A

Lovastatin

30
Q

RbS: angioedema, liver failure, birth defects

A

Lisinopril

31
Q

RbS: angioedema, birth defects, hepatotoxicity, rhabdomyolysis

A

Losartan

32
Q

RbS: hepatotoxicity, thrombocytopenia, AMI, angina

A

Amlodipine

33
Q

RbS: Cardiac arrhythmias, hepatitis, pancreatitis, SJ syndrome

A

HCTZ

34
Q

RbS: angioedema, birth defects, hepatotoxicity, rhabdomyolysis

A

Candesartan

35
Q

Efficacy: Dec. BP

A

All but statin

36
Q

Efficacy: reduction in chest pain, dec. number of weekly angina attacks, reduction in use of prophylactic nitroglycerin to relieve chest pain, improvement in s/s of HF

A

Atenelol

37
Q

Toxicity: s/s of HF, dec. HR. monitor serum electrolytes and renal function at baseline and periodically

A

Atenelol

38
Q

Counseling: Tk on empty stomach. Avoid abrupt discontinuation; exacerbations of angina may occur. Report s/s of bradycardia, hypotension, HF, or exacerbation of angina w/ initial dosing and dose changes. May cause dizziness or drowsiness. Diabetic pt. to carefully follow blood sugar lvls as beta-blockers may mask symptoms of hypoglycemia. Drug may cause sexual side effects, fatigue, and depression.

A

Atenelol

39
Q

Efficacy: Reduction in total cholesterol, LDL- cholesterol, and triglyceride levels; inc. in HDL-cholesterol levels. Assess at baseline and periodically during treatment

A

Lovastatin

40
Q

Toxicity: s/s of rhabdomyolysis or hepatotoxicity. LFTS, blood glucose, and HbA1C should be performed at baseline, 6-12 wk after initiation of therapy, and periodically thereafter; SCr kinase should be measured in pt. experiencing muscle pain and in those receiving other drugs associated w/ myopathy

A

Lovastatin

41
Q

Counseling: IR tablets should be taken w/ evening meal. ER tablets should be taken at bedtime and swallowed whole (don’t chew, crush, or cut). Avoid alcohol and grapefruit. Report s/s of rhabdomyolysis, jaundice, or renal failure. Lots of interactions. Consult PCP prior to starting any new prescriptions or OTC meds. Lovastatin does not take place of lifestyle changes to lower cholesterol levels.

A

Lovastatin

42
Q

Toxicity: s/s of angioedema, severe persistent cough, hypotension, monitor baseline and periodic electrolytes, SCr, BUN, and urine protein

A

Lisinopril

43
Q

Counseling: Avoid pregnancy. Use K supplements or salt substitutes only under medical supervision. May cause dizziness in women if dehydrated

A

Lisinopril

44
Q

Toxicity: s/s of peripheral edema. Baseline and periodic electrolyte panel, renal function tests, and urine protein are recommended

A

Losartan

45
Q

Counseling: avoid pregnancy. Avoid sudden discontinuation; rebound htn can occur. Use K supplement and salt subs under medical supervision. May cause dizziness and may worsen w/ dehydration. Seek medical attention if angioedema, excessive fluid loss, hyperkalemia, reduction in urination, or jaundice occurs

A

Losartan

46
Q

Efficacy: reduction in chest pain, dec. number of weekly angina attacks, reduction in use of prophylactic nitroglycerin to relieve chest pain, improvement in s/s of HF

A

amlodipine

47
Q

Toxicity: s/s of peripheral edema, inc. HR, LFTs

A

Amlodipine

48
Q

Counseling: Instruct pt. to report s/s of hypotension or exacerbation of angina w/ initial dosing or dose changes. Avoid alcohol. Report s/s of peripheral edema, fatigue, hypotension, or hepatic dysfunction. May cause dizziness. Avoid activities that could be dangerous if dizziness occurs at initiation of therapy. Dizziness may be worse if too much water is lost from the body due to excessive sweating, diarrhea, or vomiting.

A

Amlodipine

49
Q

Efficacy: reduction in edema

A

HCTZ

50
Q

Toxicity: Dec. serum and urine electrolytes (particularly serum sodium), dec. renal fuction, inc. serum uric acid or blood glucose. Seek medical attention if skin rash, jaundice, dec. urine output, or symptoms of gout. Dizziness, lighthededness may occur. Monitor Na, K, BUN, creatinine, skin to assess photosensitivity, skin cancer.

A

HCTZ

51
Q

Counseling: May be taken w/ or w/o food. Tk early to avoid nocturia, even if taken more than once/d. May cause dizziness. Report s/s of hypotension. Eat high-K foods during therapy. Avoid alcohol and NSAIDs

A

HCTZ

52
Q

Efficacy: resolution of HF; may require 3-6 wk to obtain therapeutic response

A

Candesartan

53
Q

Toxicity: Report s/s of hypotension, tachycardia. Baseline and periodic sodium, potassium, total bicarb, BUN, SCr, and urinalysis prior to initiating therapy.

A

Candesartan

54
Q

Counseling: Avoid pregnancy and notify physician immediately if become pregnant. Use K supplements or salt subs only under medical supervision. May cause dizziness that may worsen if dehydrated. Seek care if angioedema, excessive fluid loss, hyperkalemia, reduction in urination, or jaundice occurs

A

Candesartan

Top 300 Drugs (3 decks)

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