quiz Flashcards
a continuous molecule of DNA with associated proteins
A chromosome
22 homologous pairs of autosomes and one pair of sex chromosomes
diploid
type of cell division that gives rise to haploid gametes
meiosis
fertilization
unites gametes and restores the diploid number (46)
Mendel studied pea plants because…?
Developed quickly
Produce abundant offspring
Easy to breed
Self-fertilization yields only offspring identical to the parent
True Breeding
hybrid
Characteristics from 2 different parents
wildtype
Allele that is the most common in a population
testcross
Reveals an unknown genotype by breeding the individual to a homozygous recessive individual
Mendel’s Law of Segregation
Two alleles of the same gene separate into different gametes
Mendel’s Law of Independent Assortment and Meiosis
Inheritance of 1 gene does not affect the inheritance of another gene on a different chromosome
Independent Assortment occurs because homologous pairs of chromosomes align randomly during Metaphase I of Meiosis
linked genes
located on the same chroosomes
linkage groups
collections of genes that are often inherited together
crossing over
farther apart two linked genes are on a chromosomes
Incomplete dominance
Heterozygotes for alleles with incomplete dominance have phenotypes intermediate between those of the two homozygotes
codominance
Codominant alleles are both expressed in a heterozygote
Epistasis
One gene masks the effect of another
pleiotropic
- Gene affects multiple phenotypes
- When multiple proteins participate in a biochemical pathway, mutations in genes encoding any of the proteins can produce the same phenotype
What can alter phenotype?
environmental and genetic influences
polygenic traits
depend on more than one gene
can vary continuously in its expression
pedigree
Trace phenotypes in families and reveal modes of inheritance
autosomal dominant
- Disorder can be inherited from one affected parent
- Huntington disease-uncontrolled movements
- Marfan syndrome– Long limbs, weakened aorta
- Polydactyl- Extra fingers, toes or both
autosomal recessive
- Disorder must be inherited from both parents
- X-linked recessive disorders affect mostly males
- Cystic fibrosis-lung infection, infertility
- Albinism-lack of pigmentation
- Tay-Sachs disease- nervous system degeneration
x-linked recessive disorders
**affect more males than females
Hemophilia A – Uncontrolled bleeding
Red-green color blindness
Duchenne Muscular dystrophy-muscle degeneration