QUIZ 4 Flashcards
Symptoms of withdrawal usually begins 4 to 12
hours after cessation or marked reduction of
alcohol intake
Coarse hand tremors,
Sweating
3. Elevated pulse and blood pressure
4. Insomnia
5. Anxiety
6. Nausea and vomiting
Severe or untreated withdrawal may progress to
transient hallucinations, seizures
Delirium Tremens”
Alcohol withdrawal usually peaks on the
2nd day
and is over in about 5 days.
a life threatening
condition and detoxification needs to be
accomplished under medical supervision.
Alcohol withdrawa
Safe withdrawal is usually accomplished with the
administration of
benzodiazepine
benzodiazepine such as
Lorazepam (Ativan ) and Chlordiazepoxide
( Librium ) or Diazepam (Valium )
Withdrawal can be accomplished by fixed
schedule dosing known as
tapering
Total
score less than 8 indicate
mild withdrawal
8 to 15 means
moderate
greater
than 15 indicate
severe withdrawal
PHYSIOLOGIC EFFECTS OF LONG TERM
ALCOHOL USE
Cardiac Myopathy
Wernicke Encephalopathy
Korsakoff Psychosis
Acute
neurological condition characterized by clinical triad
of opthalmoparesis
Wernicke Encephalopathy
This is life threatening condition brought
about by thiamine deficienc
Wernicke Encephalopathy
is a late
complication of persistent Wernicke
encephalopathy
Korsakoff Psychosis
Korsakoff Psychosis ( is a late
complication of persistent Wernicke
encephalopathy, results in
memory deficit, confusion and behavioral changes
it occurs in 80%
of untreated Wernicke encephalopathy severe
alcoholism is the underlying condition
Pancreatitis
Esophagitis
Hepatitis
Cirrhosis
Leukopenia
Thrombocytopenia
Ascites
the most
frequently abused drugs in this category.
Benzodiazepines and Barbiturates
(benzo & barbi)
Symptoms of Intoxication:
- Slurred speech
- Lack of coordination
- Unsteady gait
- Labile mood
- Impaired attention or memory
- Stupor and coma
Benzodiazepines when taken alone orally in
overdose is not fatal but the person is
lethargic and
confused
TREATMENT
Gastric lavage & . Dialysis
contrast can be lethal when
taken in overdose
Barbiturates
Barbiturates by contrast can be lethal when
taken in overdose. They can cause:
. Coma
2. Respiratory arrest
3. Cardiac failure
4. Death
The withdrawal syndrome is characterized by
symptoms that are the opposite of the acute
effects of the drug
. Autonomic hyperactivity ( increased pulse, blood
pressure, respirations and temperature )
2. Hand tremor
3. Insomnia
4. Anxiety
5. Nausea
6. Psychomotor agitation
are drugs that stimulate or excite the central
nervous system and have limited clinical use
Stimulants
) this was popular in
the past, they were used by people who
wanted to lose weight quickly or stay awake
Amphetamines ( Uppers )
n illegal drug with virtually no clinical
use in medicine is highly addictive and a
popular recreational drug because of the
intense and immediate feeling of euphoria it
produces.
Cocaine