Quiz #3 Flashcards
Inflammatory vs Noninflammatory Joint Disease is differentiated by
Absence of synovial membrane inflammation, lack of systemic s/sx, normal synovial fluid analysis
Degenerative joint disorder with a progressive loss of articular cartilage accompanied by new bone formation and capsular fibrosis, usually affects weight bearing joints (hands, elbow, feet) and variable degrees of synovitis and thickening of the joint capsule
Osteoarthritis
Name some of the manifestations of OA
Pain, stiffness, enlargement of the joint, tenderness, limited motion, and deformity
What are some of the goals of therapy for OA?
Early elimination of risk factors, early diagnosis, surveillance of the disease, appropriate treatment of pain and maximize/encourage mobility
What is crepitus?
Continuous grating sensation caused by irregular cartilage, may be felt or heard as the joint is put through passive ROM
What is the primary drug of choice for pain relief of OA? What are the risks?
Acetaminophen/Risk for liver damage if pt takes >4,000mg QD, have concurrent alcoholism, or have pre-existing liver disease
This OTC topical salicylate is useful for some pts as a temporary pain reliever. How does it work?
Aspercreme. It works by blocking substance P, a neurotransmitter for pain
If acetaminophen or topical agents are not successful, what else can be used?
NSAIDs, work by inhibiting COX-1 and COX-2. COX-2 manages pain and inflammation w/ fewer side effects of GI distress/bleeding
What are some of the nursing issues for a pt with OA?
Mobility, pain, risk for injury (falls, surgical complications/medication toxicity), pre-op care and post-op care
This connective tissue disease is one of the most common and is the most destructive to the joints. It is a chronic, progressive, systemic inflammatory AI disease that primarily affects the synovial joints
Rheumatoid arthritis
Rheumatoid factors consist mainly of what two immunoglobulins?
IgG and IgM
Early systemic clinical manifestations of RA include
Low grade fever, fatigue, weakness, anorexia, and paresthesias
Treatment of RA includes
Salicylates, NSAIDS (COX-2), Ibuprofen and Celebrex
These types of drugs can be prescribed to slow the progression of mild rheumatoid disease before it worsens
DMARDs (Disease modifying antirheumatic drugs)
Name 3 DMARDS
Plaquenil an antimalarial drug, Azulfidine, and Minocycline