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IPC > Quiz 3 > Flashcards

Quiz 3 Flashcards

1
Q

bleeding from anticoagulation (coagulation + hematology labs)

A

INR, aPTT, Hgb, PLTs

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2
Q

synthetic function (coagulation + LFT labs)

A

PT/INR, aPTT

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3
Q

LFT (hepatocellular injury)

A

ALT, AST

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4
Q

excretory function (LFTs)

A

bilirubin, ALP, GGT

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5
Q

detoxification

A

ammonia

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6
Q

synthetic function

A

albumin

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7
Q

infection (hematology)

A

WBC

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8
Q

Anemia hemorrhage (hematology)

A

RBCs, Hgb, HCt, MCV, MCHC, retics

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9
Q

Hemolysis (hematology)

A

RBCs, Hgb, Hct, bilirubin, haptoglobin

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10
Q

leukocytosis

A

high WBC

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11
Q

leukopenia

A

low WBC

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12
Q

most common WBC; fights bacterial and fungal infections by phagocytosis of foreign particles

A

neutrophils

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13
Q

leukopenia or leukocytosis: bone marrow suppression from chemotherapy or drugs

A

leukopenia

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14
Q

leukopenia or leukocytosis: infection or corticosteroid use

A

leukocytosis

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15
Q

erythrocytosis

A

high RBC count

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16
Q

___ are produced in the bone marrow. Transports oxygen to all organs. Life span is approx. 3 months

A

RBCs

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17
Q

which of the following components of CBC is a direct indicator of the oxygen carrying capacity of the blood?
a. RBCs
b. hematocrit
c. hemoglobin
d. WBCs

A

Hemoglobin

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18
Q

MCV

A

mean corpuscular volume

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19
Q

high MCV

A

macrocytic

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20
Q

normal MCV

A

normocytic

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21
Q

low MCV

A

microcytic

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22
Q

which is more clinically useful, MCH or MCHC?

A

MCHC

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23
Q

high MCH/MCHC

A

hyperchromic

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24
Q

normal MCH/MCHC

A

normochromic

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25
Q

low MCH/MCHC

A

hypochromic

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26
Q

__ most useful of RBC indices- used in morphologic classification for anemia

27
Q

__ is useful to identify hypochromia which indicates Hgb synthesis

28
Q

Anemia of chronic disease presents as ___, ___

A

normocytic, hypochromic

29
Q

iron deficiency causes

A

microcytic cells (low MCV)

30
Q

anemia of chronic disease/inflammation, hemolysis, hemorrhage causes

A

normocytic cells (normal MCV)

31
Q

vitamin B12 deficiency, folate deficiency causes

A

macrocytic cells (high MCV)

32
Q

T/F : elevation of RDW helps with the variability of the cells and helps with the diagnosis of mixed anemia

33
Q

reticulocytopenia

A

low reticulocyte count

34
Q

reticulocytosis

A

high reticulocyte count

35
Q

causes of reticulocytopenia or reticulocytosis: untreated iron deficiency anemia

A

reticulocytopenia

36
Q

causes of reticulocytopenia or reticulocytosis: hemolysis, hemorrhage, response to treatment of iron, B12 or folate

A

reticulocytosis

37
Q

decrease in reticulocytes indicates that the bone marrow is not producing enough __ from either not being stimulated or being suppressed

38
Q

used for monitoring response to treatment of anemia (efficacy)

A

reticulocytes

39
Q

PLT count is critical for __ and monitoring safety of certain medications

A

clot formation

40
Q

thrombocytopenia

A

low PLT count

41
Q

thrombocytosis

A

high PLT count

42
Q

causes of thrombocytopenia or thrombocytosis:
- drug induced (e.g. heparin)
- cirrhosis
- intracranial hemorrhage
- petechiae
- infection
- stress

A

thrombocytopenia

43
Q

causes of thrombocytopenia or thrombocytosis:
- microcirculatory disturbances (headache, paresthesias)
- splenectomy (no spleen)
- thrombosis
- infection

A

thrombocytosis

44
Q

T/F: heparin induced thrombocytopenia (HIT) is commonly manifests as thrombosis and no bleeding)

45
Q

anti seizure meds that can cause thrombocytopenia

A

carbamazepine and valproic acid

46
Q

__ is important in DNA synthesis, neurologic function and hematopoiesis. deficiency in tissues can exist prior to low serum levels. Intrinsic factor is necessary for active absorption in the GI.

A

B12 (cobalamin)

47
Q

__ is necessary for DNA synthesis.

48
Q
  • pernicious anemia
  • GI abnormalities
  • low intake
  • drug induced
    are causes of decreased serum __
49
Q

__ is used to identify etiology of macrocytic anemia

50
Q

t/f: if pts serum B12 is less than 400, then the pt has vitamin b12 deficiency

51
Q
  • poor nutrition
  • drug induced
  • alcohol use disorder
  • pregnancy
  • GI abnormalities
    are causes of decreased serum __
52
Q

a. serum iron
b. serum ferritin
c. total iron binding capacity (TIBC)
d. transferrin saturation (TSAT)
which is the most useful for iron tests?

A

serum ferritin

53
Q

which component of the iron studies is an accurate reflection of total body iron stores?
a. serum iron
b. ferritin
c. TSAT
d. TIBC

54
Q

which component of the iron studies is an accurate reflection of the amount of iron is readily available for erythropoiesis?
a. serum iron
b. ferritin
c. TSAT
d. TIBC

55
Q

TIBC is an indirect measure of ___

A

transferrin

56
Q

decrease of these components of the iron studies lead to iron deficiency
a. TIBC
b. TSAT
c. ferritin
d. serum iron

A

serum iron
ferritin
tsat

57
Q

decreased TIBC is caused by

A

chronic disease/inflammation

58
Q

increased TIBC is caused by ____

A

iron deficiency

59
Q

increased TSAT is caused by

A

iron overload

60
Q

cause of vitamin B12 deficiency (microcytic, macrocytic or normocytic)

A

macrocytic

61
Q

cause of folate deficiency (microcytic, macrocytic or normocytic)

A

macrocytic

62
Q

cause of iron deficiency (microcytic, macrocytic or normocytic)

A

microcytic

63
Q

anemia of chronic inflammation, acute blood loss or hemolysis (microcytic, macrocytic or normocytic)

A

normocytic

IPC (2 decks)

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