Quiz 3 Flashcards

1
Q
  • Serology: IFA, ELISA

* PCR

A

Bartonella henselae

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2
Q

• Serology
• Culture from blood (in
appropriate labs)

A

Brucella

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3
Q

• Serology: acute and
convalescent IgM/IgG
• PCR
• Elevated liver function

A

Chlamydia psittaci

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4
Q

• Serology: IFA – Compare
Phase I & Phase II Ab
• Tissue PCR

A

Coxiella burnetii

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5
Q

• Serology (may take a few
weeks to see high titers)
• PCR available some
places

A

Francisella tularensis

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6
Q
• Culture from blood, CSF, 
urine (slow growing)
• Serology possible
• Elevated liver function, 
thrombocytopenia
A

Leptospira

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7
Q

• Culture on blood agar
• Generally diagnosed
clinically

A

Pasteurella multocida

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8
Q

•Cellular invasion
•Suppression of immune
function (apoptosis, NFKB)

A

Bartonella henselae

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9
Q

•Replication w/in
macrophages
•Limits lysosome fusion
•Suppresses inflammation

A

Brucella

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10
Q

•Intracellular replication of
reticulate bodies
•Suppression of apoptosis

A

Chlamydia psittaci

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11
Q

•Invasion & growth in
macrophages in vacuole
•Granuloma, bacteremia
•LPS variation

A

Coxiella burnetii

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12
Q

•Escapes phagocyte vacuole
to replicate intracellularly
•Suppression of cytokines

A

Francisella tularensis

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13
Q

•Disruption of endothelial
barrier, circulation entry
•Capillary vascular damage

A

Leptospira

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14
Q
  • PMT A/B subunit toxin

* Capsule sometimes

A

Pasteurella multocida

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15
Q

Capillary proliferation

A

bacillary angiomatosis (BA)

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16
Q

vascular proliferation in liver, spleen

A

bacillary peliosis

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17
Q

association of two organisms which cannot exist independently

A

symbiosis

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18
Q

association in which both organisms are benefited

A

mutualism

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19
Q

association where one partner is benefited and other is unaffected

A

commensalism

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20
Q

associations where one partner is benefited and other is harmed

A

disease

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21
Q

organisms harboring adult/sexual stage of parasite

A

definitive host

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22
Q

animals which harbor same parasite species as man

A

reservoir host (definitive host)

23
Q

unusual definitive host, one that is not necessary for maintenance of parasite in nature

A

incidental host (definitive host)

24
Q

organism in which larval or asexual form of parasite undergoes process of development

A

intermediate host

25
Q

organism that carries larval or asexual form of parasite without development

A

carrier host

26
Q

object of organism responsible for transmitting parasite from one host to another

A

vector

27
Q

vector in which the parasite multiples or develops

A

biologic vector (female anopheles mosquito)

28
Q

one which transmits parasite unchanged from host to host

A

mechanical vector (housefly for entamoeba histolytic)

29
Q

schistosome pathology

A

destructive enzymes

30
Q

e. histolytic pathology

A

cell membrane pore

31
Q

trypanosomes pathology

A

endotoxins, catabolites

32
Q

malaria pathology

A

endotoxins

33
Q

ascaris pathology

A

blockage of internal organs

34
Q

Cestodes/tape worm (Diphyllobothrium latum, Taenia solium) pathology

A

blockage of internal organs

35
Q

Schistosoma mansoni & haematobium pathology

A

blockage of internal organs

36
Q

helminth larvae pathology

A

migration through tissues

37
Q

organism that doesn’t pass parasite to another host

A

dead-end host

38
Q

R0 (basic reproduction number)

A

average number of individuals who
will contract a contagious disease from one
individual who has the disease

39
Q

R>1

A

Each infected individual will go on to infect more than one other person. Number
of cases increases exponentially over time.

40
Q

R=1

A

Each infected individual will infect one other person. Cases sustain at stable level.

41
Q

R<1

A

Each infected individual will infect on average less than one other person. Fewer
people infected and cases decline.

42
Q

BCG vaccine

A

live, attenuated

43
Q

rotavirus

A

live, attenuated

44
Q

HepB

A

subunit

45
Q

DTaP

A

toxoid; subunit (pertussis)

46
Q

MMR

A

live, attenuated

47
Q

HiB

A

conjugate

48
Q

PCV 13

A

conjugate

49
Q

HPV

A

subunit

50
Q

Meningococcal

A

subunit

51
Q

VZV

A

subunit (shingles)

52
Q

influenza

A

nasal live, attenuated; inactivated; subunit

53
Q

polio

A

oral live, attenuated (OPV); inactivated polio vaccine (IPV)