Quiz 2 Flashcards
what are the congenital anomalies of the uterus?
- arrested development
- failure of fusion
- failure of resorption
arrested development
- bilateral
- unicornuate unicollis
failure of fusion
mullarian ducts fail to fuse
what can failure of fusion result in?
depends where failure occurs
- bicornuate unicollis
- bicornuate bicollis
- dideplhsys
is bicornuate unicollis one or two uteri?
defect is lower but still one uterus, more difficult to distinguish from didelphsys
is didelphsys one or two uteri?
2 separate uterus and cervix, sometimes results in 2 separate vaginas
describe bicornuate
- uterus exterior is indented where did not fuse
- failure of fusion happens more superiorly
is bicornuate or didelphsys more common?
bicornuate
what is the difference between unicollis and bicollis?
where failure of fusion occurs
can you become pregnant with bicornuate uterus?
yes but
- preterm delivery because of growth restrictions
- caesarean section
is didelphsys common or rare?
rare
can you become pregnant with a didelphsys uterus?
yes but rare
failure of resorption
- median septum does not get resorbed
- normal exterior uterine contour
- differing degrees of resorption (septate, sub septate)
- arcuate (slight dip)
septate uterus is the most common____________
“Mullerian Duct Anomaly”
what is failure of resorption associated with?
- spontaneous abortions
- fertility issues
How do we tell if there is an Anomaly with 2D Ultrasound?
Should see endometrium dividing when scanning transversely through the uterus
what is the treatment for anomaly of uterus?
hysteroscope laser the septum
what may be a reason for miscarriages?
failure resorption
when would you plan for early delivery?
failure of fusion
when would be the best time to scan for a UTERINE ANOMALY?
secretory phase
Diethylstilbestrol (DES)
Associated with Uterine anomalies
- drug taken by mother discontinued in 1971
- given in 1st trimester had direct effect on Mullerian system of fetus (crosses placenta)
what may an ultrasound of the uterus show if a mother had taken DES?
- diffuse decrease in uterine size
- irregular T-shaped uterine cavity
what are some uterine abnormalities?
- leiomyoma (fibroids)
- lipomatous uterine tumors
- leiomyosarcoma
- adenomyosis
- arteriovenous Malformations
what is a fibroid or leiomyoma?
benign solid tumor of the uterus
what is a fibroid or leiomyoma composed of?
smooth muscle cells and fibrous connective tissue
what is the most common neoplasm of the uterus?
leiomyoma or fibroid
what is the most common cause of enlargement of non pregnant uterus?
leiomyoma or fibroids
what do fibroids depend on?
estrogen (this is why they usually decrease in menopause)
what are symptoms of fibroids?
-pain
-uterine bleeding
(frequently asymptomatic)
what are the 3 classifications of fibroids?
- intramural
- submucosal
- subserosal
what is the most common fibroid?
intramural
intramural fibroid
confined to the myometrium
completely surrounded by myometrium
submucosal fibroid
- projecting into uterine cavity (distorting or displacing endo)
- produce symptoms associated with infertility
Subserosal (pedunculated subserosal & subserosal) fibroid
- projecting outward from myometrium
- distort outer contour of uterus
intraligamentous
Pedunculated Subserosal fibroid can project between leaves of broad ligament
______ of all fibroids are located in cervix
8%
what kind of fibroid would a cervical fibroid be?
any of the three
sonographic appearance of a fibroid
- hypoechoic
- heterogenous echotexture
- areas of attenuation
- frequently distort the external contour of uterus
what do we mention when describing fibroid location
- type of fibroid
- location(anterior/posterior wall, fundal, cervical)
what do we do if their are multiple fibroids?
measure the 3 largest
what is an US role for fibroids?
- location
- size
- is it a fibroid?
how do we know if fibroid is attached to the uterus?
turn on colour and put pressure
when can post menopausal fibroids increase in size?
if on HRT or Tamoxifen
Fibroids and postmenopausal women
rarely develop
usually decrease in size
become calcified
when may fibroids increase in size?
- pregnancy
- anovulatory cycles (unopposed estrogen)
which fibroid would we measure if we saw one?
submucosal because it would be the one to cause bleeding
what problems could occur with fibroid and pregnancy?
location
-check if in cervix
size
-it gets larger with pregnancy
what are the complications associated with fibroids?
- may outgrow blood supply
- degenerating or necrotic fibroids when outgrow blood supply
- pedunculated fibroids
which colour flow is usually represented with fibroids?
peripheral flow????
transabdominal for fibroids
- larger FOV
- Better assessing large fibroids
- can be missed if just using TVP
transvaginal for fibroids
- good at detecting small fibroids
- origin of large pedunculated, subserosal fibroids vs. adnexal mass
- fundal fibroids on retroverted uterus
what is the treatment of symptomatic fibroids?
- uterine artery embolization
- surgical treatment (hysterectomy)
- medical treatment
are Lipomatous Uterine Tumors or Lipoleimyomas bengin or malignant?
benign
what do Lipomatous Uterine Tumors or Lipoleimyomas consist of?
- mature lipocytes
- smooth muscle
- fibrous tissue
what does Lipomatous Uterine Tumors or Lipoleimyomas look like sonographically?
- highly echogenic
- absence of color flow within
- usually asymptomatic
- make sure within uterus
what can Lipomatous Uterine Tumors or Lipoleimyomas be confused with?
ovarian dermoid
Leiomyosarcoma
- rare
- malignant
- may arise from leiomyoma
- asymptomatic or uterine bleeding
- same symptoms and appearance “fibroid”
what is the clue to Leiomyosarcoma?
rapid growth and post menopausal growth
Adenomyosis
endometrial glands and stroma within myometrium
what are the 2 forms of Adenomyosis?
- diffuse
- nodular
Adenomyosis diffuse
- more common
- widely scattered adenomyosis foci within the myometrium
Adenomyosis nodular
composed of adenomyomas (circumscribed nodules)
what is the clinical presentation of Adenomyosis?
Nonspecific
- Uterine enlargement
- Pelvic pain
- Dysmenorrhea
- Menorrhagia
- Seen more in women who have had children
which probe is better for looking at adenomyosis?
transvaginal
sonographic features of adenomyosis?
Diffuse ut enlargement
- Diffusely heterogeneous myometrium
- Asymmetrical thickening of myometrium
- Inhomogeneous hypoechoic areas
- Myometrial cysts
- Poor delineation of endo-myometrial border
- Focal tenderness with transvaginal transducer
- Subendometrial echogenic linear striations
- Subendometrial echogenic nodules
what can be confused with adenomyosis?
fibroid
Lieomyomas
- usually well defined
- peripheral vascularity
Localized Adenomyomas
- ill defined borders
- internal vascularity
Arteriovenous malformations (AVM’s)
Vascular plexus of arteries and veins with no capillary network
what are the most cases for Arteriovenous malformations (AVM’s)?
- pelvic trauma
- surgery
- gestational trophoblastic neoplasia
what is the symptom for AVM’s?
severe vaginal bleeding
when is AVM usually diagnosed?
post abortion and postpartum periods
what is the sonographic appearance of AVM’s?
- multiple tortuous anechoic structures
- subtle myometrial heterogenicity
- myometrial or endometrial mass
what does colour look for AVM’s?
coloured mosaic pattern
what does spectral doppler look for AVM’s?
- high velocity
- low resistance arterial flow
- high venous velocity (like an artery)
Differential Diagnosis of AVM’s
- retained products of conception (RPOC)
- GTN (gestational trophoblastic neoplasia)
- subinvolution of placental bed
what help to distinguishing differential diagnosis of AVM’s?
negative hCG
what is the treatment for AVM’s?
-Wait to see if resolve (maybe not AVM)
-severe bleeding immediate treatment
(embolization)
Monckeberg’s Arteriosclerosis
Form of arteriosclerosis
-Hardening of the vessels or calcification of blood vessels
what is found in Monckeberg’s Arteriosclerosis?
calcium deposits are found in the muscular middle layer of the walls of arteries (the tunica media)
where does Monckeberg’s Arteriosclerosis occur?
- peripheral
- coronary arteries
- GENITAL ORGAN ARTERIES
what is the cause of Monckeberg’s Arteriosclerosis?
unknown
what is Monckeberg’s Arteriosclerosis associated with?
- Diabetes
- Chronic kidney disease
- Lupus
- Chronic inflammatory conditions
what are sonographic features of adenomyosis?
Diffuse ut enlargement
- Diffusely heterogeneous myometrium
- Asymmetrical thickening of myometrium
- Inhomogeneous hypoechoic areas
- Myometrial cysts
- Poor delineation of endo-myometrial border
- Focal tenderness with transvaginal transducer
- Subendometrial echogenic linear striations
- Subendometrial echogenic nodules
is it normal to have fluid in the endo?
small amount
when measuring endo, do we include the fluid in our measurement?
NO
what are the indications for pelvic ultrasound specific for endometrium?
Bleeding
- irregular
- heavy
- spotting
what are causes for endometrial thickening?
- pregnancy
- retained products of conception
- fibroids (submucosal)
- endometritis
- adhesions
- hyperplasia
- polyps
- carcinoma
when can endometritis occur?
- postpartum
- after D&C
- associated with PID
what is the sonographic appearance of endometritis?
- thick or irregular
- may or may not contain fluid
- gas with acoustic shadowing
what are some causes of abnormal bleeding from the endometrium?
especially in post menopausal women
- hyperplasia
- polyps
- endometrial carcinoma
- atrophy
what is endometrial hyperplasia?
overgrowth of endometrial glands
what are the 2 types of endometrial hyperplasia?
hyperplasia
cystic hyperplasia
what is the most common reason for hyperplasia?
unopposed estrogen stimulation in peri/post menopausal women
what are risk factors for hyperplasia?
- Anovulatory cycles
- Polycystic ovarian disease
- Obese women (increase in estrogens)
- Estrogen producing tumors
what does hyperplasia cause?
common cause of abnormal bleeding
what is the sonographic appearance of hyperplasia?
thick
echogenic
well defined endometrium
may have cystic areas