Quiz 2 Flashcards

1
Q

Local control of flow by resistance vessels requires

A

constant perfusion pressure (MAP)

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2
Q

What are 3 keysites of MAP regulation

A

heart
resistance vessels
blood volume

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3
Q

What are the two ways that the heart is regulated intrinsically?
–which one is more significant

A
  1. preload–starling’s law
  2. homeometric–treppe
    - -starlings
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4
Q

sympathetic stimulation (increase/decrease) heart rate and (Increase/decrease) contractility and thus (Increase/decrease) stroke volume and output

A

increase

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5
Q

Parasympathetic (increase/decrease) HR and CO

A

decrease

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6
Q

atropine blocks para/sympathetic?

A

parasympathetic

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7
Q

propanolol block para/sympathetic

A

sympathetic

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8
Q

muscarinic is receptor for

A

acetylcholine

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9
Q

b adrenergic is receptor for

A

norepinephrine

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10
Q

adrenal medulla releases

A

epi and norepi

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11
Q

adrenal medulla is part of sympathetic/parasymp

A

symp

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12
Q

norepi and epi do what to heart rate and contractility

A

increase

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13
Q

Why do athletes have slower heart rate

A

increased vagal tone and slower intrinsic SA firing rate

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14
Q

t/f adrenal cortex is under control of the sympathetic nervous system

A

f

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15
Q

adrenal cortex releases what 2 things

A

corticosteroids and aldosterone

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16
Q

thyroid hormone does what to heart rate and contractility

A

increase

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17
Q

What is proportionality of resistance to radius

A

R~ 1/r^4

18
Q

What are 3 ways that resistance is intrinsically controlled?

A
  1. Basal tone/tension
  2. Myogenic response/ Bayliss
  3. local metabolites
19
Q

increased/decreased adenosine leads to vasodilation

A

increased

20
Q

increased/decreased PO2 leads to vasodilation

A

decreased

21
Q

increased/decreased pH leads to vasodilation

A

decreased

22
Q

increased/decreased CO2 leads to vasodilation

A

increased

23
Q

increased/decreased K+ leads to vasodilation

A

increased

24
Q

autoregulation is a combo of what two things

A

vasodilators/ myogenic response

25
Q

washout of vasodilators causes contraction/dilation

A

contraction

26
Q

sympathetic innervation and alpha adrenergic receptors that cause ________ are on VSM are present where?

A

all vascular beds except placenta

27
Q

does the parasympathetic innervation play a large role in regulation of MAP

A

no

28
Q

parasympathetic vasoconstriction/vasodilation

A

vasodilation

29
Q

does sympathetic play a large role in MAP reg

A

yes

30
Q

sympathetic vasoconstriction/vasodilation

A

vasoconstriction

31
Q

There is a resting sympathetic/parasympathetic tone?

A

sympathetic tone

32
Q

What contributes to basal tone of VSM?

A

myogenic and sympathetic

33
Q

withdrawal of sympathetic tone results in what two things

A

vasodilation and decreased TPR

34
Q

norepi constrict/dilate

A

constrict

35
Q

epi dilate/constrict

A

low doses dilate

36
Q

Vasopressin dilate/constrict

A

vasoconstrict

37
Q

Angiotensin II dilate/constrict

A

vasoconstrict

38
Q

Histamine dilate/constrict

A

vasodilate

39
Q

Bradykinin dilate/constrict

A

vasodilate

40
Q

prostaglandin is an endothelial mediator dilate/constrict

A

DILATE

41
Q

EDRF (endothelial derived relaxing factor) dilate/constrict

A

dilate/constrict

42
Q

endothelin is an endothelial mediator dilate/constrict

A

constrict