Quiz 2 Flashcards
study guide
What do we call receptors that react to acetylcholine?
Cholinergic
What do we call receptors that react to norpinephrine?
Adrenergic
What happens in the airways when we block the parasympathetic response?
Bronchodilation and decreased secretions
What happens in the airways when stimulate a sympathetic response?
Bronchodilation- increased HR, RR, and BP
What do adrenergic agonists drugs do at their receptor site?
Stimulate norepinephrine or epinephrine receptors
What receptor site do adrenergic agonist drugs affect?
noepinephrine
What do anticholinergic drugs do at their receptor sites?
Block acetylcholine receptors
What receptor site do anticholingergic drugs affect?
Acetylcholine
Which muscarinic receptor is important to RT’s and why?
M3 —- because it is present on airway smooth muscle, submucosal glands, and epithelial cells. Stimulation causes bronchoconstriction and glandular secretion from mucous gland s as well as increased ciliary beat
Which beta receptor do we target to get smooth muscle relaxation?
Beta 2——> relaxes bronchial smooth muscle and vascular beds of skeletal muscle
T/F Airway mucous glands have both alpha and beta receptors and are innervated by both sympathetic and parasympathetic nerves
True!
A massive discharge of parasympathetic stimulation is called SLUD, What does SLUD stand for????
Salivation, Lacrimation, Urination and DEFACATION
Where do alpha receptors cause and action when activated? what is the action?
Generally excite or stimulate with the exception of the intestine and CNS receptors where inhibition or relaxation occurs.
Alpha 1 excitation—–> vasoconstriction
Alpha 2 ——-> inhibition effect, inhibits NE release in presynaptic neuron
What organs does beta stimulation generally affect? What do they cause?
The heart—–> increases the rate and force of cardiac contraction
Which Receptors, when stimulated increase the rate and force of contraction in the heart?
Beta 1 Receptors
How long does it generally take for SABAs to reach peak effect?
60 minutes
How long does the effect of SABAS generally last
5 hours
When would you use an ultra short acting adrenergic drug as an RT?
Strong alpha adrenergic vasoconstricting effect: reduces airway swelling after extubating during epiglottis, croup or bronchiolitis to control airway bleeding during bronchoscopy
What are the generic names of the LABA’s we reviewed?
Salmeterol ( Severent)
Formoterol ( Foradil)
Aformoterol ( Brovana)
Indacaterol ( Arcapta, neohaler)
Olodaterol ( Stiverdi Respimat)
SABAS are XXX and LABAs are XXX
Relievers; Controllers
Why would an RT use lebalbuterol vs albuterol
Albuterol raises HR , Levalbuterol has more B2 specificity which will not increase HR
