Quiz 2 Flashcards

study guide

1
Q

What do we call receptors that react to acetylcholine?

A

Cholinergic

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2
Q

What do we call receptors that react to norpinephrine?

A

Adrenergic

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3
Q

What happens in the airways when we block the parasympathetic response?

A

Bronchodilation and decreased secretions

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4
Q

What happens in the airways when stimulate a sympathetic response?

A

Bronchodilation- increased HR, RR, and BP

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5
Q

What do adrenergic agonists drugs do at their receptor site?

A

Stimulate norepinephrine or epinephrine receptors

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6
Q

What receptor site do adrenergic agonist drugs affect?

A

noepinephrine

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7
Q

What do anticholinergic drugs do at their receptor sites?

A

Block acetylcholine receptors

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8
Q

What receptor site do anticholingergic drugs affect?

A

Acetylcholine

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9
Q

Which muscarinic receptor is important to RT’s and why?

A

M3 —- because it is present on airway smooth muscle, submucosal glands, and epithelial cells. Stimulation causes bronchoconstriction and glandular secretion from mucous gland s as well as increased ciliary beat

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10
Q

Which beta receptor do we target to get smooth muscle relaxation?

A

Beta 2——> relaxes bronchial smooth muscle and vascular beds of skeletal muscle

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11
Q

T/F Airway mucous glands have both alpha and beta receptors and are innervated by both sympathetic and parasympathetic nerves

A

True!

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12
Q

A massive discharge of parasympathetic stimulation is called SLUD, What does SLUD stand for????

A

Salivation, Lacrimation, Urination and DEFACATION

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13
Q

Where do alpha receptors cause and action when activated? what is the action?

A

Generally excite or stimulate with the exception of the intestine and CNS receptors where inhibition or relaxation occurs.
Alpha 1 excitation—–> vasoconstriction
Alpha 2 ——-> inhibition effect, inhibits NE release in presynaptic neuron

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14
Q

What organs does beta stimulation generally affect? What do they cause?

A

The heart—–> increases the rate and force of cardiac contraction

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15
Q

Which Receptors, when stimulated increase the rate and force of contraction in the heart?

A

Beta 1 Receptors

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16
Q

How long does it generally take for SABAs to reach peak effect?

A

60 minutes

17
Q

How long does the effect of SABAS generally last

A

5 hours

18
Q

When would you use an ultra short acting adrenergic drug as an RT?

A

Strong alpha adrenergic vasoconstricting effect: reduces airway swelling after extubating during epiglottis, croup or bronchiolitis to control airway bleeding during bronchoscopy

19
Q

What are the generic names of the LABA’s we reviewed?

A

Salmeterol ( Severent)
Formoterol ( Foradil)
Aformoterol ( Brovana)
Indacaterol ( Arcapta, neohaler)
Olodaterol ( Stiverdi Respimat)

20
Q

SABAS are XXX and LABAs are XXX

A

Relievers; Controllers

21
Q

Why would an RT use lebalbuterol vs albuterol

A

Albuterol raises HR , Levalbuterol has more B2 specificity which will not increase HR

22
Q
A