Quiz #2 Flashcards
What is a biomarker?
What does it involve?
Describe?
Involves the use of biologically available
chemicals inside the body that perform as
objective indicators of health/nutrition status
Involves a nutritional biomarker:
* An organic test used as an indicator of nutritional
status if it relates to the intake or metabolism of dietary
components
* Can be a biochemical, functional, or clinical index of
the status of an essential nutrient / dietary component
What is the function of biomarkers vs the effect of biomarkers?
Function
*Function biomarkers: help describe the role
of specific nutrients and potential interactions
between different nutrients in biological
systems.
*They also classify the roles of nutrients across
the lifespan and under different physiological
states.
Effect
Effect biomarkers: help us understand the
direct and indirect results—that is, those
affecting cells and those affecting system
function—of a nutrient deficiency.
What are four types of anemia?
Describe each?
Iron-deficiency anemia (Thalassemia): depletion of iron/poor iron absorption.
Pernicious anemia: a decrease in red blood cells that
occurs when the intestines cannot properly absorb vitamin
B12. (can cause megoblastic anemia to result)
Megoblastic anemia (large RBCs): Megaloblastic anemia is the main clinical indication of folate and vitamin B12 deficiency.
Hemolytic anemia: Hemolysis: The rupture or destruction of RBCs. Hemolytic anemia can occur as a result of hereditary or acquired disorders.
What are serum protein tests?
Creatine
Dietary protein
Albumin
Prealbumin (Transthyretin)
Transferrin
Retinol Binding Protein (RBP)
What are serum mineral tests related to iron?
Iron
Serum Ferritin (Iron)
Soluble Transferrin Receptor (sTfR)
Hematocrit
Mean Corpuscular Hemoglobin (MCH)
Mean Corpuscular volume
Iron
What are serum mineral tests
Iron related
Zinc
Calcium
Iodine
Phosphorus
Potassium
Sodium
What are serum Vitamin tests?
A
D
C
B6 (pyridoxine)
B9 (folate)
B12 (Cobalamin)
What are serum blood chemistry tests?
Alanine Aminotransferase (ALT)
Bilirubin
Blood urea nitrogen (BUN)
Carbon dioxide (CO2)
Cholesterol
LDL
HDL
Triglycerides
Blood glucose
A1C
4 general categories of biomarker tests?
Protein
Minerals
Vitamins
Blood chemistry
What does creatinine protein assessment measure?
Measures kidney function, high with muscle wasting or
malnutrition
What does dietary protein assessment measure?
Measures nutrient intake
What do albumin measurement indicate?
Low with acute infection, trauma
High with dehydration
(maintains oncotic pressure)
What does prealbumin (transthyretin) test measure?
high/low with liver disease; inflammation
What does transferrin do?
Transports iron from absorption centers in the
duodenum (intestines) and white-blood-cell
macrophages to all tissues
What do Retinol Binding protein (RBP) test indicate?
High with chronic illnesses (i.e. Type 2 Diabetes)
What does serum ferritin (iron) test indicate?
Low with iron-deficiency anemia
High in autoimmune conditions
What does soluble transferrin receptor (sTfR) and transferrin rest indicate?
High with iron-deficiency anemia