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Pharmacology Quiz 2-5 > Quiz 2 > Flashcards

Quiz 2 Flashcards

0
Q

Definition of pharmacotherapeutics

A

Study of meds affect patient

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1
Q

What is pharmacology?

A

Study of how substances affect living tissue, including how these agents bind to receptors to enhance or inhibit fcn

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2
Q

Definition of pharmacodynamics

A

What the drug does to the body

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3
Q

study of pharmacokinetics

A

Study of the bodies effect on the drug

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4
Q

Name of the drug in Dr. Breslin’s lawn that can kill you if you eat it

A

Digitalis

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5
Q

Name of the drug that is found to be good for brain tumors

A

Thalidomide

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6
Q

FDA approval process: Preclinical work

A

Drug tested on animal models

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7
Q

FDA approval process: Phase 1

A

Drug tested on healthy human volunteers

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8
Q

FDA approval process: Phase 2

A

Drug tested on Small groups of people who have the disease for which the drug is thought to be of use

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9
Q

FDA approval process: Phase 3

A

Larger groups of individuals are studied taking the drug.

The FDA can improve a drug for marketing at this stage

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10
Q

FDA approval process: Phase 4

A

Post market studies and surveillance to further determine efficacy and safety

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11
Q

Name of act which was instilled in 1970 which helped control drugs on the market

A

The comprehensive drug abuse prevention and control act of 1970

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12
Q

What is a schedule 1 drug

four examples

A

Highest potential for abuse and most addictive

Ecstasy LSD marijuana heroin

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13
Q

What is a schedule 2 drug

some examples

A

has high potential for abuse and addiction

pure stimulant or pure opiate such as oxycodone hydromorphone morphine Dexedrine

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14
Q

What is a schedule III drug?

Examples?

A

Less potential for abuse and addiction and schedule I and II

Combo drugs such as anabolic steroids hydrocodone/acetaminophen and codeine/acetaminophen

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15
Q

What is a schedule IV drug

Some examples

A

Less addictive and potential for abuse than schedule III

Examples include Valium Ativan Xanax Ambien and sonata

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16
Q

What is a schedule V drug

some examples

A

The absolute least addictive of all known drugs

Cough syrups containing Codeine

17
Q

How are drugs classified for pregnant people

A

Category A-ok (best),
B good (most common)
category X dangerous

18
Q

What is a chemical name?

A

Scientific name describing molecular structure

19
Q

What is a generic name, example?

A

Nonproprietary name which is usually an abbreviation of the chemical structure
Acetaminophen

20
Q

What is a brand or trade name

Some examples?

A

The marketing team selected by the drug company

Advil and Tylenol

21
Q

What is a drug class

A

Family name of that drug and drugs of similar chemical structure and function

22
Q

what is a PDR?

A

Physicians desk reference

They are now sleeves within drug containers which describes the precautions and Contraindications of drugs

23
Q

Order of how drugs go through the human body (5)

A

Administration, absorption, Distribution, metabolism, elimination

24
Q

What is the fastest method of drug administration? what is the slowest method?

A

IV fastest method

Oral tab slowest method (first pass)

25
Q

Injections via (deltoid) muscle or (gluteal) fat faster administration

A

Kicks in faster in the deltoid muscle than in the fat of the glute region

26
Q

Drugs which are acids prefer what kind of environment
Drugs which are basic prefer which kind of environment
examples of both

A

Acid likes acid
Base Likes Base
the stomach is an example of acid
Intestines are an example of basic

27
Q

What kind of drugs pass best through the brain and fetus

A

Lipid soluble

28
Q

What is a substrate?

A

A substance that is affected by an enzyme

29
Q

What does a drug inhibitor do?

A

Decreases enzyme so less substrate is metabolized

Increases the effact of substrates

30
Q

What are the effects of drug inducers?

A

Increases the enzyme and increases metabolism of the substrate
Decreases affect of substrate

31
Q

How many half-lives does it take to get a drug completely out of the system

A

Five

32
Q

If the half-life of a drug is 15 hours what is the calculation and how long will it take it to leave the body?

A

15 hours times 5 equals 75 hours to leave the body

33
Q

Receptors function like a ________ that opens a neural path when the proper ligand is inserted

A

Keyhole

34
Q

Correct order of what occurs at the site of drug action (4)

A

Synthesis, release, interactions, transmitter effects

35
Q

In order for an action potential to occur what mineral is needed to power it

A

Calcium

36
Q

What is a drug receptor affinity

A

the attractiveness of drug and receptor

Whichever drug has an higher affinity will gain the slot

37
Q

Agonist drugs have two of which characteristics

A

Affinity and efficacy

38
Q

What is an antagonist drug

A

Interact with the receptor but do not change it

Have affinity but no efficacy

39
Q

What is a competitive antagonist?

A

Competes with agonist for receptor, however once it is in the receptor no function occurs until the cell dies

40
Q

The greater the therapeutic index is the drug more lethal or safe?

A

The greater the therapeutic index the more safe the drug

the more narrow the index the more dangerous the drug

Pharmacology Quiz 2-5 (3 decks)

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