QUIZ Flashcards

1
Q

is a gradual and progressive process and at birth the lngs have only reached the basic functioning to support extrauterine life.

A

Fetal Lung developmemt

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2
Q

the alveoli develop in increasing number until what age?

A

8 years

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3
Q

a full term infant has estimated how many alveoli?

A

50 million alveoli to 250 million

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4
Q

Day 26-52

A

embryonal(trachea,major bronchi)

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5
Q

day 52 to week 16

A

pseudoglandular(remaining conducting airway

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6
Q

week 17- week 26

A

canalicular( vascular bed, framework of respiratory acini

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7
Q

week 26- week 36

A

saccular( increased complexity of saccules

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8
Q

week 36 to term

A

alveolar

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9
Q

includes primitive lng development and is generally regarded to encompass the first 2 months of gestation

A

embryonal phase

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10
Q

lung begins to emerge as a bud from the pharynx

A

26 days after conception

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11
Q

left and right pulmonary artery and veins start to develop

A

week 5

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12
Q

during the embryonal phase, the respiratory epithelium develops from an area of the endoderm reffered as

A

foregut bud

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13
Q

this also develops during embryonal stage of lung development

A

diaphragm

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14
Q

complete development of the diaphragm

A

week 7 of gestation

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15
Q

the respiratory epithelium begins to grow during?

A

embryonic phase(day 1 - 26)

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16
Q

the lobar bronchi form two branching from the left bud and three from the right.

A

31 days

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17
Q

this will develop into the pulmonary interstitium, smooth muscle , blood vessels and cartilage

A

mesenchyme

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18
Q

when will the diaphragm form from five different elements within mesoderm

A

starting 31 days and ending about 7 weeks

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19
Q

failure of the diaphragm to completely close during this phas results in

A

congenital diaphragmatic hernia occuring in 2000 to 4000 births

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20
Q

this sis named after the distinct glandular appearance of the developing lung

A

Pseudoglandular phase

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21
Q

pseudoglandular phase extends to week?

A

16 of gestationstation

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22
Q

the most distal structure

A

terminal bronchioles

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23
Q

this wee the airway has branched to about 4 generations

A

week 7

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24
Q

in this week the major lobes of the lung are identifiable

25
smooth muscle around the airways begins developing around
weeks 10 and 24
26
immature cartilage begins too form around
week 11
27
cilia appear on the surface of the lungs epithelium starting at
10 weeks to 13 weeks
28
the presence of mucus can be found in the fetal lung starting at
week 13
29
cells that are responsible for creating mucus
goblet cellsl
30
this phase is so named bec of the appearance of vascular channels, or capillaries, that begin to grow
canalicular phase
31
during the canalicular period that are consist of respi bronchiole, alveolar ducts and sacs
acinar unit
32
Pulmonary acinar units are also formed in this period
canalicular period
33
what consist of the acinar unit?
respiratory brochiole, respiratory sac, respiratory ducts
34
the survival of fetus become possible at
week 22-24 gestation
35
the canicular lungs stage
week 17-26
36
this part has no cartilage and are prone to airway collapse
respiratory bronchiole
37
this is secreted by epithelial cells of the lungs to help patency of the airway
fetal lung fluid
38
fetal lung fluid seceretes how many ml
250 to 300 ml
39
the volume of fetal lung approximates the
FRC
40
Approximately 26- 36 weeks gestation
saccular phase
41
at the beginning of this stage the terminal saccules are formed
saccular phase 26 weeks gestation
42
during this phase there is marked an increased in the potential gas exchanging surface area
saccular phase
43
true alveolar appear at about 30 weeks in the airways distal to the terminal bronchioles, forming, short, shallow sacs
saccules
44
Each saccule is made up of type I and type II cells and functions as an ?
alveolar-capillary membrane
45
Saccules are closely grouped, making the space between them, called the? also is is twice as thick as an alveolar wall.
the septa
46
toward the end of this phase at about week 35 this one begins to appear.
mature surfactant
47
a neonate born at this point is at minimal risk for pulmonary complications at birth caused by?
lung immaturity
48
distinction between the saccular and alveolar phases is somewhat?
arbitrary
49
these are the primarily a postnatal event, extending beyond birth with rapid growth up to 18 months post-gestation.
alveolar maturation and proliferation
50
it is characterized by a complex interaction of epithelial, fibroblast, and vascular growth factors with extracellular matrix components.
Alveologenesis
51
It has been estimated that only how many percent of the adult number of alveoli are present at birth, and thus alveologenesis is largely a postnatal event.
15% to 20%
52
this phase begins at about week 36, approximately I month before a full-term delivery. Alveoli are quickly proliferating during this phase, growing in number to the millions by the time of delivery.
The alveolar phase
53
There is published evidence to show that the number of alveoli present in the lungs at term range from how many?, with other data
zero to 50 million
54
how many fold that the lung volume increases
23-fold
55
how many fold that the alveolar number increases
6-fold
56
how many fold that the alveolar surface increases
21-fold
57
how many fold that the lung weight increases
20-fold
58
Lung volume increases disproportionally to what?
alveolar number.