Quiz 1 Wordbank Flashcards
Anti-oncogenes (aka tumor-supressor genes)
Genes that tell cells to stop multiplying
Benign
Tumors that are generally well differentiated and do not metastasize or invade surrounding normal tissue. They are often encapsulated and slow growing
Biopsy
Surgical removal of a small tissue sample from a solid tumor to determine the pathology for the diagnosis of disease
Carcinomas
Tumors that originate from the epithelium and include tissues that cover a surface or line a cavity
Epidemiology
Study of defining the distribution and determinants causing disease and injury in human populations
Etiology
Study of the causes of disease
Grade
Grade of a tumor provides information about its biological aggressiveness and is based in the degree of cell differentiation. For some tumors, such as high-grade astrocytoma, grade is the most important prognostic indicator
Malignant
Tumors that are malignant often invade and destroy normal surrounding tissue and, if left untreated, can cause the death of the host
Necrosis
Death or disintegration of a cell or tissue caused by disease or injury
Palliation
Noncurative treatment to relieve pain and suffering when the disease has reached the stage at which a cure is no longer possible
Prognosis
Estimation of life expectancy
Prospective study
Study in which the theory of the cause of a condition or disease is tested by examining those who have a particular characteristic or trait.
Proto-oncogenes
The normal genes that play a part in controlling normal growth and differentiation
Radioprotectors
Certain chemicals and drugs that diminish the response of cells to radiation
Radiosensitizers
Chemicals and drugs that help enhance the lethal effects of radiation
Retrospective study
Studies that review information from a group of patients treated in the past
Sarcomas
Tumors arising from mesenchymal cells or connective tissue
Stage
Cancer is “staged” after a histologic diagnosis is made. Staging helps determine the anatomic extent of the disease. Treatment decisions are based on the histologic diagnosis and extent of the disease
Systemic treatment
Killing cells if the primary tumor and those that may be circulating through the body
Therapeutic ratio
Delivering the maximum amount of radiation needed to kill the cancer while sparing normal surrounding tissue.