QUIZ 1 - INTRODUCTION Flashcards
It is the invasion and growth of harmful microorganisms.
Infection
Community of microorganisms that normally exists in a particular environment.
Microbiota/Microbiome
Agents that cause infections or organisms that can cause disease.
Pathogens
Types of Pathogens
Bacteria
Protists
Fungi
Virus
Viroid
Prion
Non-living pathogens
Fungi
Port of Entry of Microorganisms:
Epithelial Surface
Direct Contact
Port of Entry of Microorganisms:
Respiratory
Inhalation/Droplets
Port of Entry of Microorganisms:
Gastrointestinal
Ingestion
Port of Entry of Microorganisms:
Genitourinary
Sexual Transmission
Port of Entry of Microorganisms:
Hematologic
Systemic/Blood Pressure
Port of Entry of Microorganisms:
Neurologic
CNS Spread
Port of Entry of Microorganisms:
Lymphatic
Lymph fluid spread
Two Infection Prevention
- Anatomical Barriers
- Physiologic Protection
What are the Anatomical Barriers?
- Intact Skin
- Mucous Membrane
- Ciliated Epithelial Lining
- Intact Endothelium
- Blood Brain Barrier
What are the Physiologic Protections?
- Sloughing of skin/mucus membrane
- Coughing/sneezing
- Vomiting/ increased intestinal motility
- Mucous/salivary and other enzymes and body fluid secretions
- Increase intestinal motility
Examples of Phagocytes
Neutrophils, Monocytes, Macrophages
The Central Signaling System
Inflammasomes
Other important players in infection control and prevention.
- Phagocytes
- Inflammasomes
- Complement Component
- C-reactive Protein
- Microbiome of the Host
- Circulating Antibodies
Immune Responses
- Adaptive Immunity
- Innate Immunity
Example of Adaptive Immunity
- Humoral/B Cell Immunity
- Cellular/T Cell Immunity
Which cells are involved in Innate Immunity?
- Granulocytes (Basophil, Eosinophil, Neutrophil)
- Mast Cell
- Natural Killer Cell
- Complement Protein
- Dendritic Cell
- Macrophage
How to maintain the balance?
The host and the pathogens must be balance in the environment.
Factors that determine the severity of infection.
- Location of the Infection
- Population of the Pathogens
- Virulence of the Microorganisms
- Immune Response of the Host
The environment must be/have:
- Optimal
- Favorable
- Adequate Nutrients
To prevent infection, the host must monitor their:
- Nutritional Status
- Health Condition
- Immunocompetent/Immunosuppressed
Profile of Patients with Dental Infection
Developed Countries
- Elderly
Developing Countries
- Teens and Adult
Both
- Immunocompromised
- With chronic diseases
- Pregnant
- Malnourished
How to achieve optimum oral health?
- Good education
- Good oral health practices
- Availability of oral health services
- Accessibility to dental services
- Sufficient fund for preventive
oral health programs - Sustainable oral health care program
Human harbors a complex ecosystem of _____________ that has important role in health and disease.
Microbial flora (microbiome)
The normal human harbors more than __________ more microbial cells than human cells
10 Times
Most of the commensal organisms coexist with _________.
Human Host
They help prevent infectious diseases.
Microorganisms
TRUE OR FALSE: Pathogenic organisms exhibit wide range of virulence.
True
Produced disease in a high fraction of healthy individuals.
Highly Infectious
Other microbes are minimally pathogenic requiring __________________________.
Large Exposure and Concomitant Breaches of Host Defenses
Contributors to Dental Infection
- Oral Health Providers
- Poor sterilization of Instruments and galenicals
- Inadequate dental/medical history taking
- Lack of knowledge in the choice of antibiotics
- Inadequate information/instruction to patients
that may lead to patient poor compliance
- Undetected patients medical co-morbidities - Patient
- Inadequate oral health education
- Poor oral hygiene practices
- Insufficient to zero dental checkup
- Non-accessibility to potable water
- No accessibility to dental services
We used it in most activities we do everyday. Its movements are directed by our brain so it can it either protect us or harm us.
Hands
The rate of how communicable diseases can be transferred by touch.
80%
Example of Communicable Diseases that can be transferred by touch:
- food and water borne diseases
- skin diseases
- sore eyes (conjunctivitis)
- respiratory diseases
- blood borne diseases
- brain and spinal cord infection
Dirty Things we touch daily:
- Sponges, Dirty Dishes, Tooth brush holder
- Remote Control
- Cutting board
- Cell phone, IPOD
- Grocery cart
- Purse, Wallet
- Door Knob
- Refrigerator handle
- Comfort Rooms, Toilets
- Dental floss
Average number of times we touch our face daily:
2000-3000 times
Average number of times we touch or phones daily:
2617-5247 times
Number of persons that wash their hands more than 10 times per day.
- 62% women
- 37% men
Number of persons that wash their hands less than 6 times per day.
- 41% women
- 17% men
Number of persons that wash their hands after using the public toilet.
Adult - 83 %
Teen girls - 58 percent
Teen boys - 48 percent
Rate of washing hands after coughing/sneezing.
32%