Quiz 1 ID 2-3 Side Effects Flashcards
What two drugs causes diarrhea, hypersensitivity, seizures with excessive doses?
What is the class?
Carbapenem
- meropenem (Merrem)
- ertapenem (Invanz)
What drug class may cause tendinitis/ tendon rupture, peripheral neuropathy, CNS effects, and muscle weakness in patients with myasthenia gravis?
Fluoroquinoles
- ciprofloxacin (Cipro)
- levofloxacin (Levaquin)
- moxifloxacin (Vigamox, Avelox)
What drug can cause diarrhea and QTc prolongation?
- azithromycin (Zithromax, Z-Pak, Zmax)
What drug can cause diarrhea, QTc prolongation, AND a metallic taste?
- clarithromycin (Biaxin, Biaxin XL)
Which drug do you not use for systemic infections? And why?
- fidaxomicin (Dificid) is not used for systemic infections b/c there is no systemic absorption
What tetracycline antibiotic causes esophagitis and photosensitivity?
- doxycycline (Vibramycin)
What drug category may cause permanent gray-brown discoloration of teeth or enamel hypoplasia when given to children?
Tetracycline Antibiotics
- doxycycline
- minocycline
Which antibiotics should you take 2 hours before or 6 hours after products that contains divalent or trivalent cations (ex. Dairy products, calcium juices, oral multivitamins, mineral supplements)?
Hint: Two drug classes
- Tetracycline (2)
- Fluoroquinolone (3)
What drug class can cause QTc prolongation, tendon rupture, increased hepatic transaminases, photosensitivity?
Fluroquinolone (3)
- ciprofloxacin
- levoflaxacin
- moxifloxacin
What drug causes skin rashes, hyperkalemia, increased serum creating, hypersensitivity, nausea, vomiting, diarrhea?
Hint: Combo drug
Sulfonamide Antibiotic
- sulfamethoxazole and trimethoprim (Bactrim, Bactrim DS)
What is the ratio of sulfamethoxazole and trimethoprim?
Fixed ratio of (5:1); dosing based on trimehtoprim
What drug when giving in chronic use can cause pulmonary fibrosis?
Urinary Antibiotic
- nitrofurantoin (Macrobid)
What drug causes nephrotoxicity and vancomycin infusion reactions?
Glycopeptide
-vancomycin (Vancocin)
What drug causes alcohol intolerance and with long term use cause peripheral neuropathy?
It also has a metallic taste
- metronidazole (Flagyl)
Does mupirocin (Bactroban) have any major side effects?
No