quiz 1 Flashcards
DO2
what it is and equation
- oxygen delivery
2. arterial oxygen content * cardiac output
VO2
what it is and equation
- oxygen consumption
2. (arterial oxygen content - venous oxygen content)* cardiac output
OER
what it is and equation
- oxygen extraction ratio
2. oxygen consumption (VO2)/ oxygen delivery (DO2)
definition of O2 convection
movement of O2 from alveoli to tissue capillaries
definition of O2 diffusion
movement of O2 from capillaries to mitochondria
O2 convection is determined by: (3)
- [Hb]
- O2 saturation
- CO
O2 diffusion is determined by: (4)
- metabolic rate
- vascular resistance
- capillary recruitment
- tissue O2 consumption and extraction
at rest DO2 is __x times the metabolic demand in a healthy individual
4x
VO2 can increase up to __x fold in response to exercise in a healthy individual
20x
CO (def and equation)
- volume of blood being pumped out of L or R ventricle
2. stroke vol * heart rate
CO can increase up to __x fold in response to exercise demand in a healthy individual
5x
define preload
muscle fiber length of ventricle before systolic ejection
define afterload
resistance to the ejection of blood during ventricular systole
define O2 debt (2)
- recovery O2 consumption
2. difference btwn O2 demand and VO2
how does O2 demand change from rest to peak activity level?
increases