Quiz 1 Flashcards

1
Q

What is the most important antibody type for mucosa immunity?

A

IgA

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2
Q

What attracts immune cells to site of injury / inflammation?

A

Chemokines

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3
Q

What are compensation microbes an important promoter of?

A

Regulatory immune responses

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4
Q

M2 macrophages, what are they alternatively known as, what repair do they mediate?

A

Alternatively activated macrophages
Mediate wound repair

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5
Q

What is TLR4, what does it recognise

A

Toll-like receptor 4, recognises Liposaccharide (LPS) in gram negative bacteria cell wall

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6
Q

What are Langerin cells

A

Specialised dendritic cells within the skin

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7
Q

What is TSLP (thymic stromal lymphopoietin), and what is it also known as

A

An epithelial derived cytokine,
/alarmin

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8
Q

What does a paneth cell secrete in the small intestine

A

Antimicrobial peptides

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9
Q

Where do dendritic cells and T cells interact to stimulate antigen-specific immune responses

A

Lymph node

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10
Q

Apoptosis in T cells usually happens when and where?

A

Thymus (in the)
Usually in T cells that recognise self antigen

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11
Q

Activated mast cells release this biogenic amine ;

A

Hisatmine

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12
Q

Anaphylaxis is associated with changes in vascular permeability and..

A

Smooth muscle contraction

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13
Q

Mature mast cells are found in the skin, but not in…

A

Circulation

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14
Q

Binds FceRII on mast cells and crosslinking triggers degranulation

A

IgE

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15
Q

IL-2 is a cytokine, what does it do?

A

Promotes TH1 immune responses

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16
Q

Increasing the number of antigen-specific lymphocytes os called… (C… e….)

A

Clonal expansion

17
Q

Where do B cells mature?

A

Bone marrow

18
Q

What do T helped cells do

A

Activate macrophages to kill phagocytosed microbes

19
Q

What cells secrete antibodies following activation

A

B cells

20
Q

Which innate immune cells are involved in allergic immune responses?

A

Eosinophils