Quiz 1 Flashcards
What is the most important antibody type for mucosa immunity?
IgA
What attracts immune cells to site of injury / inflammation?
Chemokines
What are compensation microbes an important promoter of?
Regulatory immune responses
M2 macrophages, what are they alternatively known as, what repair do they mediate?
Alternatively activated macrophages
Mediate wound repair
What is TLR4, what does it recognise
Toll-like receptor 4, recognises Liposaccharide (LPS) in gram negative bacteria cell wall
What are Langerin cells
Specialised dendritic cells within the skin
What is TSLP (thymic stromal lymphopoietin), and what is it also known as
An epithelial derived cytokine,
/alarmin
What does a paneth cell secrete in the small intestine
Antimicrobial peptides
Where do dendritic cells and T cells interact to stimulate antigen-specific immune responses
Lymph node
Apoptosis in T cells usually happens when and where?
Thymus (in the)
Usually in T cells that recognise self antigen
Activated mast cells release this biogenic amine ;
Hisatmine
Anaphylaxis is associated with changes in vascular permeability and..
Smooth muscle contraction
Mature mast cells are found in the skin, but not in…
Circulation
Binds FceRII on mast cells and crosslinking triggers degranulation
IgE
IL-2 is a cytokine, what does it do?
Promotes TH1 immune responses