Quiz 01

Question 1

What mechanism contributes to the diversity of the mRNAs and proteins encoded by a single gene in our (mammalian) genome?

Answer 1

alternative reading frames

Question 2

Which amino acids can be phosphorylated?

Answer 2

STY (serine, threonine, tyrosine)

Question 3

What is the function of intrinsically disordered protein sequences?

Answer 3

1. cell signaling through covalent modification of protein sequence
2. Tethering to hold interacting proteins
3. formation of diffusion barrier from a dense network

Question 4

Which amino acid residues would you expect to find in the interior of protein molecules?

Answer 4

nonpolar

AVLIW
“I Would Like A Vinaigrette”

Question 5

Which amino acids are positive and negative?

Answer 5

Positive = HRK

Negative DE

Question 6

Which amino acids are polar?

Answer 6

STNQ

Question 7

Which amino acids are nonpolar

Answer 7

AVLIW MFGCP

“I Would Like A Vinaigrette” For My Great Chicken Pasta

Question 8

An enzyme acts on a tyrosine residue in a target protein to create a binding site for a SH2 domain. This enzyme is?

Answer 8

kinase

Question 9

What happens to a reaction A –> with a negative G value under experimental conditions?

Answer 9

Increasing the concentration of B molecules would increase the G value (toward more positive values)