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IPE Pharmacology > Quick Study Side Effects > Flashcards

Quick Study Side Effects Flashcards

1
Q

Side effects of ACEi

A 
Cough
Postural hypotension (with Diuretics)
Angioedema 
Renal dysfunction
Rash
GI- diarrhoea, bloating, nausea, vomiting, changes in taste
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2
Q

Side effects of amiodarone

A 
Corneal microdeposits
Thyroid dysfunction
Hepatotoxicity
Pulmonary toxicity
Peripheral neuropathy
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3
Q

Monitoring in amiodarone

A

LFT, TFT, before and every 6 months

CXR and electrolytes before

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4
Q

CI amiodarone

A

Iodine sensitivity
Heart block
Thyroid disease
Some arrhythmics (Brady)

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5
Q

Side effects NSAIDs

A

Renal dysfunction
Increased bruising
Ulcers

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6
Q

Side effects of warfarin

A

Bleeding
Teratogenic
Necrosis of soft tissue- protein C (toes!)

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7
Q

Warfarin potentiators

A

Liver disease
High metabolic rate e.g. thyroid
Aspirin and NSAIDs

ODEVICES

OMEPRAZOLE
DISULFRAM
ERYTHROMYCIN
VALPROATE
ISONIAZID
CEMETIDINE
ETHANOL - ACUTE
SULPHONAMIDES
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8
Q

Decrease warfarin effects

A

Pregnancy
Hypothyroidism
Vitamin K- kale, broccoli

PCBRAS
PHENYTOIN
CARBAMAZEPINE 
BARBITUATES
RIFAMPICIN
ALCOHOL- CHRONIC
SULPHONYLUREAS
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9
Q

Side effects beta blockers

A 
Bradycardia
HypotensionBronchospasm
Cold fingers
Fatigue
Dizziness
Heart block
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10
Q

Side effects calcium channel blockers

A

Reflex tachycardia
Ankle swelling
Hypotension
Headache

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11
Q

Statin side effects

A 
Myalgia
GI
Hepatic
Rash
Insomnia
Myositis

Avoid grapefruit

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12
Q

Side effects SSRIs

A 
GI
Appetite and weight change
Headaches
Drowsiness (can take at night)
Anxiety (2 weeks)

Withdrawal

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13
Q

Contraindications to SSRI

A

Suicide risk—> refer

Mania

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14
Q

Monitoring in methotrexate

A

FBC, LFTs, U&Es

Before starting
Every 2 weeks until stable
Then 2-3 months

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15
Q

Sid effects methotrexate

A

Alopecia
Headaches
GI

Myelosupression

  • infection —> A&E
  • unexpected bleeding/bruising
  • Anaemia
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16
Q

Complications of methotrexate

A

Myelosupression
Hepatic- alcohol
Pulmonary- SOB

17
Q

Methotrexate contraindications

A 
Baby
Hepatic
Breastfeeding 
Infection
immunodeficiency
18
Q

Monitoring in lithium

A

Before- U&Es , FBC, TFTs, bHCG, ECG

Lithium levels weekly until stable for 4 weeks then every 3 months

TFT, U&Es Ca2+ every 6 months

19
Q

Side effects lithium

A

GI
Metallic taste
Tremor
Water symptoms- SIADH

Toxicity

  • GI
  • neuromuscular- dizziness, dysarthria, ataxia, twitching, restlessness
20
Q

Complications of lithium

A

Renal
Diabetes insipidus
Hypothyroidism

21
Q

Contraindications to lithium

A 
Pregnancy
Breast feeding
Cardiac
Renal
Addison’s
Low sodium diet
Hypothyroidism
22
Q

Onlanzapine monitoring

A

Occasional LFTs

23
Q

Side effects onlanzapine

A

Anti-dopaminergic- tardive dyskinesia, tremor, movement disorders
Anti-cholinergic- constipation, dry mouth
Anti-histaminergic- weight gain, dizziness, drowsiness
Anti-adrenergic- hypotension

24
Q

Complications onlanzapine

A

Neuroepilaptic malignant Syndrome

  • Fever
  • Muscle rigidity

Agranulocytosis

  • Infections
  • swelling
  • rash
25
Q

Contraindications onlanzapine

A

Liver failure
Phaeochromocytoma

Cautions
Epilepsy
DM
Glaucoma
Parkinson’s
Heart, prostate, kidney problems
Pregnancy
26
Q

Levodopa side effects

A

Psychosis
N&V
Dyskinesia
Postural hypotension

Drugs can help

Contraindicated in glaucoma

27
Q

Side effects bisphosphonates

A 
Headache
Heartburn
Bloating
Indigestion
GI
28
Q

Contraindications for bisphosphonates

A

Pregnancy
Dysphagia
Ulcers
Renal

29
Q

Levothyroxine monitoring

A

Test dose- 2-3 weeks
TSH every 2/3 months until stable
TSH annually if stable

30
Q

Side effects levethyroxine

A

Rare

May be hyperthyroid, or hypo if levels are too low

31
Q

Side effects metformin

A

Nausea, diarrhoea, abdopain, weight loss

32
Q

Contraindications metformin

A

Renal
Ketoacidosis
Low BMI

If miss a dose, take asap, but not if close to next dose

33
Q

How take iron tablets?

A

Work best if empty stomach

Most take with food as can cause GI upset

34
Q

Monitoring iron tablets

A

Takes 3-4 weeks to increase Hb ( FBC)

3 months to replenish stores

35
Q

Side effects iron tablets

A

GI - nausea, sickness, diarrhoea, abdo pain
Coloured stools
Taste bad

IPE Pharmacology (3 decks)

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