Quick Quiz 1

Question 0

Felix is undergoing treatment of tuberculosis. Which of the following drugs used in treating TB are potentially hepatotoxic ?

A. Isoniazid (INH) and Rifampin
B. Isoniazid (INH)
C. Ethambutol and Rifampin
D. Streptomycin

Answer 0

Isoniazid (INH) and Rifampin

Question 1

Furoncoumarins
A. Are found in grapefruit juice.
B. Are antiretroviral medications used in HIV therapy
C. Are related to aspirin, and should be avoided in children with viral infections
D. Are blood thinners.

Answer 1

Are found in grapefruit juice

Question 2

Which of the following pharmacokinetic phases involves metabolism by the CYP450 enzyme families ?
A. Drug absorption
B. Drug metabolism
C. Drug excretion 
D. Drug distribution

Answer 2

Drug metabolism only

Question 3

Encouraging full adherence to therapy against HIV infection will help prevent
A. The development of antiviral resistance
B. The appearance of opportunistic infections, like mucocutaneous candidiasis
C. Excessive morbidity and mortality
D. All of these

Answer 3

D. All of these
Adherence to therapy helps prevent the emergence of antiviral resistance, deterioration in immune function, and the appearance of secondary infections associated with immunodeficiency, like mucocutaneous candidiasis.

Question 4

A 6 year kid make patient has a viral upper respiratory infection, and notes right ear pain at the same time. Therapy for the ear pain will include 
A. Amoxicillin
B. Hydrocodone
C. Ibuprofen
D. Aspirin

Answer 4

C. Ibuprofen
For viral infections - especially at the onset of the infection- symptomatic therapy, even if possible otitis media, will include appropriate analgesia. In this instance, milder, non-aspirin drugs, are most appropriate, like Ibuprofen.

Question 5

Which of the following drugs is NOT a prodrug ?
A. Hydrocodone with APAP (Lortab)
B. Tamoxifen (Nolvadex)
C. Levofloxacin (Levaquin)
D. Enalapril (Vasotec)

Answer 5

D. Levoflaxacin (Levaquin) is not a prodrug

Question 6

A child presents with open wounds to lips and her skin looks burned after a course of antibiotics. This represents which of the following ?
A. A potentially serious adverse drug reaction
B. The Stevens-Johnson Syndrome
C. A side effect of certain drugs for which the etiology is incompletely understood
D. All of the above

Answer 6

D. All of the above

SJS is a serious, potentially fatal, drug reaction, and the etiology is not clearly understood.

Question 7

Patient presents to clinic with sudden appearance of frequent, painful urination. She’s even healthy but engaging in sexual intercourse for past 3 days. She’s not on any medication and has know allergies. UA confirms diagnosis of cystitis and she needs an antibiotic. First line therapy is:
A. Doxycycline (Vibramycin)
B. Azithromycin (Zithromax)
C. Trimethoprim/Sulfamethoxazole (Septra)
D. Ampicillin (Principen)

Answer 7

D. Trimethoprim/Sulfamethoxazole (Septra)

First time symptomatic cystitis or UTIs in women, Septra is drug of choice

Question 8

With respect to excretion of drug metabolizes, phase I and phase II metabolism:
A. Make products more effect
B. Increases storage of the drugs in body fat
C. Make the metabolizes more soluble in water
D. Permit resorption of the metabolites within the kidneys.

Answer 8

C. Makes the metabolites more soluble in water

Phase I and II drug metabolism allows for greater water solubility to promote the excretion of a given drug.

Question 9

Which of the following antimicrobial drugs, ordered as shown, would be MOST effective and LEAST expensive, when used for the initial empiric treatment of a furuncle on the nose?
A. Zyvox
B. Amoxicillin
C. Trimethoprim/Sulfamethoxazole 
D. Vancomycin capsules

Answer 9

C. Trimethoprim/Sulfamethoxazole

This is inexpensive and effect antibiotic that will cover staph and strep that could. Be in this drainage, including MRSA

Question 10

Paul has a rash on his chin that is “soupy” draining a lot of pus each day. You feel that it is certainly impetigo. Which organisms are most likely to be cultured from the pus ?
A. Carbapenem-resistant Entrrobacteriacae
B. Staphylococci and Streptococci
C. Vancomycin-resistant Staphylococci
D. Rhinovirus or Adenovirus

Answer 10

B. Staphylococci and Streptococci

Impetigo is most often caused by typical skin organisms: staph and strep species

Question 11

Most drugs in current use are metabolized by which CYP450 enzyme family?
A. 2C19
B. 2C9
C. 2D6
D. 3A4

Answer 11

D. 3A4

Approximately half of all drugs are metabolized, in whole of part, by CYP3A4