Questions I got wrong :( Flashcards
List 6 measurable markers of an effective interprofessional team
- Patient-centred care (ease of referral, EBM, outcomes)
- Interprofessional communication (how, how often)
- Participatory leaders/Collaborative leadersip
- Conflict resolution mechanisms (e.g. complaints, M&Ms, suggestions)
- Clearly defined roles/responsibilities
- Team function/teamwork (how is this measured?)
Can be thought of as
- structure
- process
- outcomes
I’m still not sure what the exact answer to this is.
8 nonpharma prevention/treatments for delirium
- Reorientation
- Visual/hearing aids
- Early/regular mobilisation
- Monitor bowel/bladder function
- Sleep hygiene/routines
- Monitor nutrition/hydration
- Deprescribe
- Familiar people/objects
2 rx + 4 non-rx treatments for neuropathic pain
- Anticonvulsants
- Antidepressants
- Massage
- Mindfulness based therapies
- Acupuncture
- CBT
- Neuroablation surgeries/interventions
Which CYP metabolises methadone?
Name 2 inhibitors
Name 2 inducers
CYP 3A4
- Grapefruit juice inhibits
- Erythromycin inhibits
- Haloperidol inhibits
- Carbamazepine induces
- Dexamethasone induces
- Phenytoin induces
When do fentanyl pharmacokinetics change?
- TD form + hyper or hypothermia
- TD form + severe cachexia (anything that lowers Vd)
6 symptoms to expect after d/c hemodialysis
- Confusion
- Nausea/vomiting
- Itch
- Myoclonus
- Fatigue
- Dyspnea
- Pain
- Anxiety
- Depression
What are the 3 core components of the burnout syndrome?
- Depersonalisation/loss of empathy
- Emotional exhaustion
- Loss of sense of personal accomplishment
You have a new consult and you’re not feeling up to it (i.e. burned out). List 3 things you would check with yourself before doing that consult.
- Am I emotionally exhausted?
- Am I capable of empathy?
- Have I lost my sense of personal accomplishment?
No idea if this is the right answer.
8 non-symptom topics to discuss with a family toward EOL
- DNR
- SDM
- Family can be present, talk, touch, etc.
- Cultural norms they would like respected
- Funeral home contact
- Crisis preparation (what might happen, what the plans are)
- Nutrition education
- Prognosis/what to expect
6 non-rx pain management techniques for infants
- Distraction with toys/bubbles, etc.
- Music
- Swaddling
- Cuddling parent
- Sugar
- Calm environment
4 aspects of decisionmaking capacity
Understanding of illness/situation
Appreciation of risks/benefits of options
Reasoning ability to make a decision
Communication ability to express decision
8 vulnerable populations
- Indigenous
- Immigrant
- Children/dependent adults
- Unhomed
- Minority sexuality
- Minority race
- Low SES
- Rural/remote community
- Cognitive or physical disabilities
- Mental health/addictions
4 strategies to have culturally sensitive GOC discussions
- Interpreters
- Ask patient/family how they want to receive information
- Solicit agenda/questions
- Establish decisionmakers based on pt/family presence
4 causes of respiratory congestion at EOL
- Terminal upper airway secretions
- Pulmonary edema/fluid overload
- Lymphangitis
- TE fistula
- Pulmonary hemorrhage
- Pneumonia
What behavioural changes may indicate a child is in pain? (6)
- Loss of interest in surroundings
- Inconsolability
- Appetite changes
- Sleeplessness
- Grimacing/vocalising
- Irritability
- Poor performance in school
- Resistance to being moved
6 risk factors for bleeding in the cancer setting.
- Thrombocytopenia, any cause
- Anticoagulant medications
- Large central lung tumour
- ENT malignancy
- High-dose radiation
- Severe liver disease
3 rx + 3 non-rx treatments for ALS sialorrhea
- TCAs
- Anticholinergics
- Botox
- Suction
- Salivary gland XRT
- Parasympathetic nn ablation
6 risk factors for depression, not disease related
- Female sex
- Younger age
- FHx of MDD
- Personal hx of MDD
- Poor social supports
- Poor physical symptom management
3 tx for nonmalignant pleural effusion at EOL
- Tunnelled pleural catheter (allows drainage as outpatient)
- Diuresis (e.g. if CHF)
- Symptom management (e.g. opioids, O2 for dyspnea)
List 4 categories of interventions for dysphagia
- Dietary/texture modifications
- Enteral feeding
- Structural interventions (stenting, dilation)
- Oral care
- Positioning when eating
- Parenteral feeding
6 reasons a patient with SUD might overuse opioids
- Pseudoaddiction
- Poor absorption/rapid metabolism
- Diversion
- Euphoria/side effects
- High opioid tolerance
- Misunderstanding of dosing (e.g. thinking q1h prn dose is to be taken regularly)
4 causes + 1 invx of acute dyspnea/hypoxemia
- PE
- Pneumonia
- Pneumothorax
- Pulmonary edema/AECHF
- SCVO
CT
4 steps of confusion assessment before invx
CAM
1. Acute change, fluctuating
2. Attention assessment
3. Cognitive assessment (esp. orientation, psychosis)
4. Altered LOC
5. Review potential organic causes (i.e. H&P, chart review, med review)
4 considerations when family want feeding in dementia
- Explore family fears/needs/understanding
- Limited benefits of enteral feeding
- Harms of enteral feeding (bleeding, pain, infection, medicalisation, aspiration risk)
- Explore feeding at risk
- Explore reasons they may not be eating
6 components of a new palliative care program
- Existing resources (i.e. who is currently caring for this population)
- Who will the population be?
- Who will staff the service (which allied teams)
- Funding
- Where will care be provided (inpatient, outpatient, community, LTC)
- Referral / triage criteria and processes
- EBM options
4 relative contraindications to THC
- Cardiac risk factors
- Severe hepatic or renal failure
- Preexissting mood disorder
- Preexisting SUD
4 indications for an intrathecal pump
- Pain refractory to systemic analgesia
- Patient intolerant of systemic analgesia
- Good response to trial epidural/spinal
- Intractable tenesmus
- Locoregional pain
6 symptoms of complicated grief
Symptoms >1 year:
1. Rumination
2. Persistent intense longing for decedent
3. Social function impaired
4. Work function impaired
5. Denial
6. Anger
7. Intrusive thoughts about decedent or death
8. Suicidal ideation
4 mx for decubitus ulcers
DIME
1. Downloading
2. Infection prevention/treatment
3. Moisture mangement (dressings, continence products)
4. Edge effects (debriding, surgery, hyperbaric O2)
DSM-V criteria for delirium
- Acute onset / Fluctuating course
- Inattention + altered awareness
- At least 1 other cognitive deficit (e.g. disorganisation, disorientation, language alterations)
- Not explained by a baseline cognitive issue
- Organic cause identified
4 psychosocial issues to consider in a child with Duchenne
- Body image issues
- Processing his shortened life
- Sexuality/puberty
- Maintaining normalcy (school, peer relations)
- Distress at functional changes
Son requests you don’t tell his mother about her cancer diagnosis. List 5 considerations as you approach this.
- Explore son’s fears/goals/needs
- Explain to him your legal responsibility
- Speak to her directly, but plan discussions with son to allow him to feel he has a say
- Professional interpreters if there is a language barrier
- Establish patient wishes and autonomy
6 specific questions in dignity-conserving care
- What are some of the most important moments in your life? When did you feel most alive?
- What were some of your biggest accomplishments?
- What roles are you most proud of filling? What do you think you achieved in those roles?
- Do you have any life advice for family or friends?
- Do you have any instructions going forward?
- Do you have anything left unsaid?
- What would you most want to be remembered for?
- What are your hopes and dreams for your lived ones?
4 ways to increase access to PC in unhomed
- Partner with existing healthcare outreach
- Partner with existing resource services (e.g. housing)
- Mobile- or shelter-based teams
- Educating staff about needs more common in this population, including a resource limited setting
5 systemic barriers to home discharges
- Lack of equipment
- Lack of formal caregivers
- Lack of medication access/ease of administration
- Need for adequate informal caregivers as ADLs decline
- Medical needs (subq sites, tubes, CSCIs, lifts) requiring skills
4 aspects of PC that improve with reflection
- Reduced burnout/unplanned time off
- Improved patient satisfaction
- Improved practitioner satisfaction
- Improved empathy
5 causes of hiccups in cancer
- Central structural causes
- Iatrogenic (esp. dex)
- Diaphragmatic/phrenic irritation
- Airway irritation
- Ascites
- Gastroparesis/gastric obstruction
- GERD
Why not to suddenly d/c Parkinson’s meds
Parkinsonian crisis/NMS mimic “DAWS”
- abrupt functional decline
- rigidity
- ANS dysfunction
- confusion
- anxiety/depression
- craving dopamine agonists
- death
4 non-pharm treatments for SBO nausea/vomiting
- Bowel rest
- Venting (NGT/PEG)
- Stenting if able
- Excellent oral care
- IVF (isn’t this pharmacological?)
5 dyspnea strategies in ALS (not treating the cause)
- Positioning (upright when able)
- Breathing techniques / exercises
- NIPPV if hypoxemic
- Opioids for dyspnea
- Calm environment
4 types of terminal diseases that lead to depression
- ENT cancers
- CHF
- Dementia
- Progressive neurodegenerative conditions
6 strategies to manage opioids in substance abuse setting
- Long-acting formulations preferrable
- Adjuvant therapy to spare doses
- Taper if able (e.g. after XRT)
- Do not ignore/undertreat pain just because of SUD
- Shorter prescriptions, single-prescriber, single pharmacy
- Engage support network in managing pain
- Monitor for interactions with recreational drugs
Codeine enzyme; codeine in kids?
CYP 2D6
No codeine in kids–metabolism unpredictable and hypermetabolisers can overdose, while immature CYP enzymes may mean limited benefit.
SICG Components
- Set up conversation
- Assess illness understanding
- Assess information preferences
- Share prognosis
- Explore goals, fears, strengths, trade-offs etc.
- Close conversation
- Document
6 complicated grief risk factors
- Age >60
- Female
- Poorer
- Marginalised population
- Any psychiatric history
- Loss of child
- Loss of spouse
- Young decedent
- Death by trauma
- Multiple losses
4 treatments for DM gastroparesis
- Glycemic control
- Dietary modifications
- D2 antagonists
- Erythromycin
4 complications of celiac axis entrapment
- Gastroparesis
- Gastric outlet obstruction
- Obstructive hepatic failure
- Mesenteric ischemia
- Bleeding/clotting in celiac vessels
- Abdominal pain
4 indications for methadone
- Neuropathic pain
- Chronic nonmalignant pain
- Pain in renal failure
- Poor oral absorption
- OUD
List the 5 phases of reflection on a difficult encounter, error, etc.
- Describe the facts
- Describe your feelings
- Describe where things went wrong
- Review what could have been done differently
- Review what will be done differently next time
3 things to ask yourself when you don’t feel like a consult
I still don’t have an answer.
4 reasons you need to adjust dosing in peds
- Wee organs
- Immature enzymes
- Reduced glycoproteins
- Altered surface-area-to-volume ratio
- Altered fat-to-lean ratio
SCC–how to decide on XRT alone vs surgery + XRT
- Multilevel vs. single-level disease
- Performance status
- Radioresistant/sensitive tumour
- Radiosaturation
- +/- Metastatic disease
- Unstable fracture
- Goals of care
3 solid tumours associated with hyperCa
- Lung ca
- Breast ca
- Prostate ca
- Renal ca
3 CNS causes of fatigue
- Structural disease
- Post-WBR
- Dementia
- Lack of sleep
3 paraneoplastic sydromes that cause fatigue
- Lambert-Eaton Syndrome
- Hypercalcemia
- SIADH
- Limbic encephalitis
4 red flags in dyspnea that indicate urgent assessment
- Hypoxemia
- Stridor
- Fatiguing
- Marked tachypnea
- Marked new tachycardia
- Altered LOC
4 treatments of urinary fistulae
- Symptom palliation
- Surgical diversion
- Surgical repair
- Obstructive stenting (e.g. in ureter)
4 mechanisms of opioid-induced vomiting
- CTZ
- Gastroparesis
- Constipation
- Vestibular activation
5 areas where pharmacokinetics are different in kids (which is increased?)
- Absorption
- Distribution
- Metabolism I
a. faster prepuberty - Metabolism II
- Elimination
Absorption of dermal medications increased 2* area/volume ratio
6 steps in planning a family meeting
- Patient (or SDM) permission to arrange a meeting
- Identify reasons/agenda per care team + patient
- Chart review
- Review of previously-stated wishes, ACP, etc.
- Review social context of patient (e.g. home setup)
- Identify who should be present (from care team and from patient team)
- Identify a quiet, private space for the meeting with adequate chairs + time that works
5 serious risks of IVR interventions
- Bleeding
- Perforation of hollow viscus
- Infection
- Iatrogenic / thrombotic embolus
- Nerve damage
4 drugs that interact with cannabis
- Additive sedation with sedatives
- Induces olanzapine clearance
- Induces theophylline clearance (only when smoked)
- Increases INR on warfarin
4 factors that increase the perception of pain
- Opioid neurotoxicity
- Fear of what the pain signifies
- Anxiety, depression, negative houghts
- Lack of control, or feeling thereof
- Hypervigilance around pain
6 functions of PC associations that lets them advocate for palliative pts
- Public awareness campaigns
- Professional education
- Advocacy for policy change/resources
- Advocacy for medication access
- Social supports for palliative patients/families
- Networking between professionals
2 nonopioid receptors methadone acts on
- NMDA antagonism (S-methadone)
- SNRI (S-methadone)
- ACh antagonism
Distinguish NMS from serotonin syndrome.
Both:
- hypertension
- tachypnea/cardia
- hyperthermia
- sweating
NMS:
- hyporeflexia
- severe rigidity–“lead pipe”
- no GI symptoms
- high WBCs
- low iron
SS:
- hyperrflexia + clonus
- pupils dilated
- GI symptoms
4 components of existential distress
- Fear of death
- Meaninglessness
- Regret about opportunities/unfinished business
- Isolation
- Loss of control
List 5 considerations/foci when assessing confusion in a patient on opioids who does not want investigations.
- Full medication review
- S/sx evidence of infection
- S/sx of neurotoxicity
- Is it delirium?
- Assess GOC for empiric treatment
- Chart review for pre-existing contributors (e.g. structural disease, known cognitive impairment, known organ failure)
Pediatric mg/kg/dose morphine for:
- pain
- dyspnea
Pain: 0.3mg/kg/dose, q4h
Dyspnea: 0.15mg/kg/dose, q4h
What is the calcium correction formula?
[40 - (patient albumin)]*0.02 + measured Ca
e.g. 2.83, albumin 26
= [40-26]*0.02 + 2.83
= 0.28 + 2.83
= 3.11
This formula is outdated.
3 treatments for bladder-ca-induced hematuria.
No XRT.
- Systemic or local TXA
- CBI
- Cystoscopic cautery
- Local styptic (e.g. silver nitrate, alum)
In a 17yo with Ewing sarcoma met. ++ to lung, list 5 non-pain emergencies at EOL
- 1 drug + route to treat any
- Delirium
- Hemoptysis/bleeding
- Dyspnea crisis
- SVCO
- Symptomatic hypercalcemia
- Spinal cord compression
Midazolam subq
Match the drug with the symptom:
Symptoms:
Restless leg syndrome
Sleep disturbance
Alterations in taste and smell
Hiccups
Neuropathy
Medications:
Baclofen
Cannabis
Methadone
Pramipexole
Zinc
- Restless leg syndrome + pramipexole
- Sleep disturbance + cannabis
- Dysgeusia/anosmia + zinc
- Hiccups + baclofen
- Neuropathic pain + methadone
6 drug classes for tenesmus
- Topical anesthetics
- CCBs (e.g. nifedipine)
- Anticholinergics
- Opioids
- Stool softeners/osmotic laxatives
- Steroids
4 skin changes in chronic/late lymphedema
- Thickening/pitting
- Exaggerrated skin folds
- Chronic inflammation/erythema
- Papillomata
- Hyperkeratosis
3 differences between moisture dermatitis and pressure ulcer
- Location (skin folds/gluteal cleft vs. bony prominences)
- Necrosis (not present in dermatitis)
- Shape (“kissing” spots, diffuse spots in moisture vs. round/well defined in pressure)
- Edges (less distinct in MD)
- Depth (rarely any depth to MD)
- Colour (more variegated, blanchable in MD)
4 topical treatments for bleeding in malignant wounds
- TXA
- Styptics (silver nitrate, alum)
- Pressure dressings
- Calcium alginate dressings
- Cautery
- Epinephrine
4 treatment for malodorous wounds
- Topical antibiotics
- Debridement of necrotic tissue
- Environmental techniques (essential oils, kitty litter, ventilation)
- Charcoal dressings
4 indications for paracentesis in PC
- Abdominal discomfort
- Squashed stomach syndrome (NV, early satiety, reflux)
- Dyspnea 2* elevated diaphragm
- Diagnosis (e.g. suspicion of infection)
- Unresponsive to diuresis
4 side effects of cannabis
- Drowsiness
- Dry mouth
- Anxiety
- Confusion
4 validated pain scales in a nonverbal child.
FLACC
- face, legs, activity, cry, consolability
CHEOPS
- Children’s Hospital of Eastern Ontario Scale
FACES
Visual analog scale
5 reasons non-medical interpreters are a bad idea in palliative care
- They have the role of delivering bad news
- Limited medical knowledge/vocabulary
- Cannot confirm information being conveyed is correct
- They may not want to know everything they are required to translate
- Emotional stress added to having an ill parent
- They are caught between the doctor and family
Describe the 4 stages of pressure wounds
- At risk, blanchable redness.
- Nonblanchable redness, no breakdown
- Epidermal breakdown, dermis visible
- Skin breakdown, subcut fat visible +/- slough
- Full-thickness breakdown to connective tissue +/- slough
X. Excessive slough or eschar make staging impossible
4 chemical ligands involved in pain transduction
- Histamine
- Bradykinin
- Serotonin
- Heat/cold
- Prostaglandins
- Substance P
- Nerve Growth Factor
4 pathophysiological characterstics of neuropathic pain
- Related to direct nerve damage
- Experienced in distribution of nn.
- Associated with peripheral and central sensitisation (e.g. allodynia)
- Associated with nonpainful neuropathy such as numbness, tingling, dysesthesias
- Typical pain features (e.g. burning, electric)
4 steps in neurophysiology of pain
- Transduction (peripheral nn)
- Transmission (peripheral nn, spinal cord)
- Modulation (spinal cord, brainstem, thalamus)
- Perception (cortex)
4 factors that affect opioid pharmacokinetics
- Hepatic function
- Renal function
- Fat:lean ratio (esp. fentanyls, methadone)
- Age
- Perfusion/hypotension
What is lidocaine traditionally used for? (2)
- Local anesthesia
- Antiarrhythmic
What is the half-life of lidocaine?
1.5-2h
Name 6 blood tests in a breast cancer patient with nausea
- Na+
- Ca++
- Cr/BUN
- Bilirubin + ammonia
- CBC (esp. WBCs)
- Cultures
- Glucose
- TSH
Name 4 contraindications to ketamine
- Pregnant/breastfeeding
- Psychotic disorder
- Elevated ICP
- CHF or recent ACS
- Hypertension
Onset of po ketamine
30 min.
4 medication classes that can cause constipation
- Opioids
- Anticholinergics
- TCAs
- 5-HT3 antagonists
- Iron
- CCBs
- L-dopa
- Antihistamines
- Antidiarrheals
4 classes of oral laxative
- Stimulant
- Stool softener (e.g. docusate)
- Osmotic
- Lubricant
- Oral opioid antagonists (e.g. naloxegol)
- Bulk-forming
4 classes of medication to manage complete SBO
- Somatostatin analogues
- Non-prokinetic antinauseants (e.g. ondansetron, Haldol)
- Steroids
- Antispasmotics
- Other antisecretory agents (PPI, H2RA)
4 complications of PEG insertion
- Bleeding
- Infection
- Gastric perforation
- Pain
4 poor surgical prognostic factors in SBO
- Poor functional status
- Ascites
- Peritoneal/omental disease
- Extensive extraabdominal disease
- Low albumin/cachexia
- Multifocal obstruction
4 elements of CAM
- Acute onset/fluctuating course
- Inattention
- Disorganised thinking
- Altered LOC
1 + 2 + either 3 or 4
Lewy body dementia + delirium–first line drug
Quetiapine
3 most common symptom indications for palliative sedation
- Refractory delirium
- Refractory dyspnea
- Refractory seizures
2 parameters measured in palliative sedation
- Responsiveness/LOC
- Signs of discomfort (e.g. grimacing, tachypnea)
- Family coping
4 s/e from bisphosphonates
- Uveitis
- Mandibular necrosis
- Influenza-like symptoms
- GI upset/esophagitis
- Bone pain
4 nonpharmacological management of secretions in a waking cystic fibrosis pt
- Positioning
- Good hydration
- Oral care
- Shallow suctioning
- Cough assist devices
- Chest physiotherapy
5 signs + their etiologies that can help determine cause of dyspnea
- Tachycardia = tachyarrhythmia
- Wheeze = obstructive lung disease
- Paradoxical breathing = respiratory muscle weakness
- Unilateral leg swelling/heat/tenderness = VTE
- Reduced a/e + dullness on percussion = pleural effusion
- Localised crackles/egophony = pneumonia
- Pallor = anemia
4 symptom mx for dyspnea crisis in lung mets; GOC M1
- Oxygen (humidified)
- Opioids
- Upright positioning
- Anxiolytics/sedatives
- Emotional support/presence
4 physical exam findings in SCVO
- Facial / arm swelling
- Distended neck vv.
- Distended hand vv. that do not collapse w. elevation
- Dysphonia/hoarse voice
- Altered LOC
- Conjunctival edema
6 s/sx of severe anxiety
- Sweating
- Tremor
- Palpitations/tachycardia
- Chest tightness/pain
- Nausea
- Muscle tension
- Insomnia
- Trouble concentrating
3 medication classes that can cause/worsen anxiety
- Stimulants
- Corticosteroids
- Decongestants
- Theophylline
- High-dose serotonin agents (SSRI, SNRI)
- Thyroxine
4 substances from which withdrawal can trigger anxiety
- Alcohol
- Opioids
- Nicotine
- SNRIs/SSRIs
- Benzodiazepines
4 risk factors for depression + malignancy
- Pain
- Metastases
- ENT tumour
- Female sex
- Vinca alkaloids
- Personal/FHx depression
Endicott Scale–2 cognitive components
- Depressed affect
- Social withdrawal
- Pessimism/brooding
- Reduced responsiveness
4 characteristics of complementary/alternative medicine users
- Women
- Gyne cancers
- From cultures with strong traditions
- Distress of allopathic system
- Richer
- More educated
3 mind-body therapies for pain
- Hypnosis
- Mindfulness meditation
- Therapeutic imagery
- Music therapy
- Yoga
3 ways inflammatory breast ca differs from noninflammatory
Inflammatory is:
1. More aggressive
2. Associated with peau d’orange, erythema, edema
3. Less responsive to treatment
4 modalities to treat bone mets
- XRT
- Surgical fixation for specific lesions
- Bisphosphonates
- Isotope therapy (esp. radium 223 as well as iridium)
- Chemotherapy
2 criteria for tumour debulking in met breast ca
- Symptoms to justify surgery (e.g. malignant wound)
- Spinal cord compression
- Good baseline functional status
- Limited metastatic disease
4 s/e of hormone treatment for breast ca
- Depression
- Hot flashes
- Reduced libido
- Osteoporosis
- Fatigue
- Bone/joint pain
2 treatments for high-risk prostate cancer
- Prostatectomy + LN dissection
- Radical XRT
Lung cancer pathology most common in nonsmokers
Adenoca
2 paraneoplastic syndromes associated with SCLC
- SIADH
- Lambert-Eaton Syndrome
- Cushing syndrome
- Myaesthenia gravis
4 natural changes in sexual function as women age
- Reduced lubrication
- Reduced vaginal length
- Labial atrophy –> clitoral prominence
- Fragile vaginal tissue
4 causes of reduced libido in colon ca post-op
- Body image issues
- Post-operative pain
- Anxiety/depression
- Side effects of chemotherapy
- Side effects of opioids
- Fatigue
2 treatments for vaginal dryness
- Nonmedicated lubricants
- Prolonged foreplay
- Regular vaginal moisturisers
4 natural changes in sexual function as men age
- Reduced erectile tumescence
- Prolonged time to orgasm
- Reduced seminal fluid
- Prolonged refractory period
- Prolonged time to erection
4 causes of ED in prostate ca
- Post-operative changes
- Post-radiation changes
- ADT
- Depression
- Opioid therapy
4 ways to re-establish intimacy post-cancer
- Emphasise nonsexual intimacy (cuddling, kissing)
- Schedule intimacy around energy levels
- Consider aids (lubricants, toys, porn)
- Consider alternative positions that take less energy
- Masturbation to relearn what it feels like to be sexual
Advice for safe sex on chemotherapy
- Condoms/dental dams while receiving chemotherapy
- Typically 2-3 days post infusions
- Condoms on sex toys, which should also be washed
6 risk factors for colorectal ca
- Family history of colon ca
- Genetic conditions (e.g. FAP)
- Smoking
- Alcohol use
- Previous pelvic radiation
- Age >50
- High-fat diet
- IBD
6 presenting s/sx of colorectal ca
- LBO
- Incidental on screening
- Hematochezia
- Abdominal pain
- Stool changes
- Unintentional weight loss
- Abdominal mass
4 poor prognostic features of colorectal ca
- Obstructive at diagnosis
- Metastatic at diagnosis
- Advanced age at diagnosis
- High CEA
3 PE signs of advanced pancreatic ca
- Jaundice
- Cachexia
- Ascites
- Palpable liver
- Virchow’s node (L supraclavicular)
- Sister Mary Joseph nodule (umbilical)
4 features of pain associated with pancreatic ca
- Epigastric
- Radiates to mid-back
- Burning, gnawing
- Worse with po intake
- Nocturnal
- Improved when curled up
2 nonmedication ways to treat pancreatic cancer pain
- Celiac plexus block or ablation
- XRT
2 symptoms of pancreatic exocrine insufficiency
- Diarrhea/steatorrhea
- Cachexia
- Abdominal pain
- Excessive flatulence
6 clinical manifestations of pheo
- Episodic tachycardia/hypotension
- Episodic diarrhea
- Headache
- Episodic flushing
- Pallor
- Refractory hypertension
6 Ps–palpitations, poo, pain, perspiration, pallor, (blood) pressure
What pain medications should be avoided in pheochromocytoma?
- Morphine (histamine release)
- Tramadol (SNRI effect)
- Ketamine (sympathetic effect)
- Steroids (cortisol release)
- TCAs (SNRI effect)
- SNRIs/SSRIs
What nausea medications must be avoided in pheochromocytoma?
All D2 antagonists
What is the FICA mnemonic in assessing spirituality?
- Faith (any faith or spirituality?)
- Importance to their life/decisions
- Community (are they part of one? is this important?)
- Address spiritual issues
What perception is at the root of suffering?
A threat to our personal, psychological, spiritual integrity.
List 3 risk factors for existential suffering
- Poor symptom management
- Social isolation
- Immobility
- Self-blame for illness, decline, etc.
- Loss of sense of control
ABCD of dignity-conserving care
- Attitude
- Behaviour
- Compassion
- Dialogue
Duration of symptoms to diagnose complicated grief?
12+ mo
4 bedside interventions for terminal bleed
- Be calm, even if no one else is
- Dark towels
- Opioids subq/IV
- Sedatives subq/IV
- Pressure on the bleeding area
- Wound packing if from a wound
4 pharmaceutical treatments for UGIB
- PPI
- H2RA
- Somatostatin analogue
- TXA
- Vasopressin
- Stop anticoagulants/antiplatelet agents
- Vitamin K
3 contraindications to hyperbaric oxygen therapy
- Bleomycin treatment
- Untreated pneumothorax
- Recent ENT surgery
- URTi
- Pulmonary blebs
- Severe obstructive pulmonary disease
- Claustrophobia
4 contraindications to anticoagulation in DVT/PE
- Bleeding diathesis
- Thrombocytopenia <50
- Active bleeding
- GOC do not indicate
- Recent surgery
- Intracranial tumour
- Previous intracranial hemorrhage
- IT or epidural pump in place
Seizures despite phenytoin in a patient on dex for brain mets–medication options?
- Stop/reduce dex or increase phenytoin
a. dex reduces phenytoin blood levels - Levetiracetam
- Valproic acid
- Phenobarbital
- Benzodiazepines
Medication options for benzo-refractory status epilepticus
- Levetiracetam
- Phenytoin
- Phenobarbital
- Valproic acid
- Propofol
3 symptoms of progressive end stage CHF
- Syncopal episodes
- Refractory edema
- Refractory dyspnea
- Angina
- Severe fatigue
6 symptomatic indications for radiotherapy
- Pain
- Bleeding
- Seizure/brain disease
- Spinal cord compression
- Obstruction (e.g. esophagus, GOO, colonic)
- SCVO
4 acute abdominopelvic XRT s/e
- Diarrhea (enteritis/colitis)
- Dysuria/hematuria (cystitis)
- Vaginal mucositis
- Nausea/vomiting (gastritis/enteritis)
- Dermatitis
4 late s/e from oropharyngeal XRT
- Xerostomia
- Dental caries/disease
- Osteonecrosis
- Dysphagia
- Skin fibrosis
- Skin telangiectasia
3 contraindications to XRT
- Prognosis <weeks
- GOC do not indicate
- Previous radiosaturation
- Radioresistant tumour
- Large lung field + lung disease
- Pacemaker in field
- Connective tissue disease (e.g. scleroderma, lupus)
4 cardiac causes of syncope
- Valve failure
- Arrhythmia (tachy/brady)
- Ventricular failure (i.e. reduced EF 2* myopathy)
- MI
- Tamponade
4 s/e of stopping HF medications
- Increased edema
- Increased dyspnea/fluid overload
- Syncope
- Sudden death
List the components of the CHADS-2 score.
- CHF
- Hypertension
- Age >75
- T2DM
- Previous stroke (2)
CHADS-2-Vasc uses age >65
List the components of the CHA2-DS-S2-Vasc
- CHF
- Hypertension
- Age (65+ = 1; 75+ = 2)
- DM
- Sex (female = 1)
- Stroke (2)
- Vascular disease
List the components of the HAS-BLED score
- Hypertension
- Age >65 (1) + anticoagulants (1)
- Stroke
- Bleeding history
- Labile INR (1)
- Ethanol (1)
- Diseased liver (1) or kidney (1)
4 cancers with high risk for spinal cord compression
- Breast
- Lung
- Prostate
- Renal
- Lymphoma
What are the 4 stages of spinal cord compression pathology?
- Venous engorgement
- White matter edema
- Grey matter edema
- Nerve infarction
What is the main advantage of tunnelled over nontunnelled abdo catheters?
Reduced infection risk
4 triggers for worsening hepatic encephalopathy
- UGIB
- Benzodiazepines
- Constipation
- Increased protein intake
- Biliary obstruction
- Infection
- Dehydration
3 ways to improve hepatic encephalopathy
- Lactulose
- Rifamixin
- Late night snacks of complex carbs
- Reduce mitigating factors (e.g. stop alcohol, reduce protein, maintain kidney function)
- Reduce protein intake and divide through day
5 measures of Child-Pugh score
- INR
- Bilirubin
- Albumin
- Ascites
- Encephalopathy
2 preferred opioids in liver failure
- Fentanyl
- Morphine
- Hydromorphone
Sources disagree about morphine.
5 complications of dialysis
- Line infection
- Dialyser reaction
- Hypotension OR hypertension
- Chest pain/dyspnea
- Muscle cramping
- Lifestyle inconvenience
- Seizure
- Nausea/vomiting
4 treatments of CKD-associated itch
- Emolient creams
- Antihistamines
- Gabapentin
- Sertraline
- UVB
- Thalidomide
5 non-pharmacological treatments for dry skin
- Fatty creams
- Cotton gloves at night
- Clip nails
- Avoid dessicants (e.g. alcohol hand sanitiser)
- Avoid hot baths/showers
- Hypoallergenic soaps
- Humidifiers in dry environments
3 medications that can worsen restless leg syndrome
- Antihistamines (esp. 1st-gen)
- D2 antagonists
- Antidepressants (all classes)
2 drugs for muscle cramps in dialysis
- Vitamin C + E
- Gabapentinoids
- TCAs
1 way to prevent respiratory failure in ALS
Adequate vaccinations
- pneumococcal
- flu
- COVID
Treat sialorrhea
NIPPV indications in ALS
- Dyspnea
- Hypoxemia
Initiate BEFORE FVC <50%
2 rx for muscle cramping in ALS
- Baclofen
- Tizanadine
- Botox
Etiology of pseudobulbar affect in ALS?
Reduced descending inhibition 2* corticobulbar degeneration
3 neurological / 3 psychiatric / 3 cognitive symptoms of Huntington
Neurological
- chorea
- hyperreflexia
- gait disturbance
- dystonia
Psychiatric
- depression
- apathy
- paranoia
- disinhibition
Cognitive
- memory loss
- concentration loss
- loss of insight
3 causes of chorea
- Huntington disease
- Dopamine agonists
- CNS infections
- Alcohol intoxication
- Stroke
2 medications for HD + 2 main s/e
- Deu/tetrabenazine (VMAT inhib)
- Dopamine antagonists
- depression
- sedation
2 signs in multiple sclerosis
- Spasticity
- Hyperreflexia
- Intranuclear ophthalmoplegia
- Babinski +
- Ataxia
2 investigations to diagnose MS
- MRI
- Lumbar puncture for IgG bands
- Visual-evoked potentials
4 dysautonomic sx in PD
- Orthostatic hypotension
- Hyperhidrosis
- Thermoregulatory failure
- Sialorrhea
- Gastroparesis
- Constipation
- ED
How does carbidopa combine with levodopa?
It prevents peripheral conversion of L-dopa to dopamine before it crosses the BBB
List 4 systemic medications for movement in Parkinson disease
- L-dopa/carbidopa
- Rotigotine
- Pramipexole
- Amantadine
- Apomorphine
4 palliative care challenges unique to children
- Decisionmaking, especially in late-school age and adolescence
- Parental needs/wants vs. children’s
- Different medical situations
- Weight-based medication dosing
- Many orphaned/rare diseases
- Practitioner emotional overinvolvement
For each statement, state developmental stage it’s ass’d with
- understand death is final
- experience the world through senses
- see death as reversible
- understand death is caused by illness
- believe death is only caused by external factors
- understand universality of death, but not for them
- death as a “monster”
- death as punishment
- attribute life to inanimate objects
- invincibility
- understand death is final (6-8)
- experience the world through senses (0-2)
- see death as reversible (3-5)
- understand death is caused by illness (9-11)
- believe death is only caused by external factors (6-8)
- understand universality of death, but not for them (12+)
- death as a “monster” (6-8)
- death as punishment (6-8)
- attribute life to inanimate objects (3-5)
- invincibility (12+)
For each statement, state developmental stage it’s ass’d with:
a. Guilt about things said or not said, done or not done
b. Concern about personal future and security
c. Confusion about circumstances of death and a need to review it frequently:
d. Regression in behaviors, such as bed-wetting
e. Asks a lot of questions, focus on gory details
f. Blame others for the death and how it affects their life
g. Fears of changes in their world, of more family deaths
h. Covering up emotions and trying to appear normal
a. Guilt about things said or not said, done or not done (12+)
b. Concern about personal future and security (9-11)
c. Confusion about circumstances of death and a need to review it frequently: (3-5)
d. Regression in behaviors, such as bed-wetting (3-11)
e. Asks a lot of questions, focus on gory details (6-8)
f. Blame others for the death and how it affects their life (12+)
g. Fears of changes in their world, of more family deaths (6-8)
h. Covering up emotions and trying to appear normal (9-11)
For each statement, state developmental stage it’s ass’d with:
- Spirituality is imaginative, and participation in ritual becomes important
- Concern over right and wrong and connecting ritual with personal identity
- Needs include trust, a sense of hope and equanimity among others, and feelings of self worth and love
- Search for meaning, purpose, hope, and value of life, and an evolving relationship with a higher power
- Spirituality is imaginative, and participation in ritual becomes important (3-5)
- Concern over right and wrong and connecting ritual with personal identity (7-11)
- Needs include trust, a sense of hope and equanimity among others, and feelings of self worth and love (0-2)
- Search for meaning, purpose, hope, and value of life, and an evolving relationship with a higher power (12+)
4 cancers in 15-29-year-old patients
- Testicular
- Germ cell
- Lymphoma
- Melanoma
- MSK sarcoma
- Thyroid
5 issues specific to young adults when faced with cancer dx/tx
- School/career future
- Normalcy in life
- Puberty/sexuality/body image
- Independence
- Shortened prognosis
- Fertility impact
- Social isolation
4 allied health disciplines in young adult cancer patients
- Social work
- Occupational therapy
- Physiotherapy
- Spiritual care
2 resources to refer young adult patients to in Canada
- Young Adult Cancer Canada
- School counsellors
- Peer support groups
BODE Index
- BMI
- Obstruction (FEV1/FVC)
- Dyspnea
- Exercise capacity (6 minute walk)
2 nonpharmacological sx mx tips in COPD
- Quit smoking
- Keep exercising
- Inhaler technique
- Pulmonary rehab
1 indication for O2 in COPD / ILD
Why are the O2 targets different in COPD/ILD?
PaO2 <55mmHg
COPD = CO2 retention
4 stages of HIV/AIDS
- Virus but asymptomatic
- Virus + symptoms of HIV infection
- CD4 count <200 and/or AIDS-defining illness (AIDS)
- CD4 counts <50 (advanced/late AIDS)
4 accelerated nonninfectious conditions in HIV
- Atherosclerosis
- Dementia
- Neuropathy
- CHF
- COPD
- Renal failure
- Osteoporosis
- Depression/anxiety
- Frailty
1 reason to continue HAART in late-stage HIV
Infection or viremia can be symptomatic
2 reasons to stop HAART/antibiotics in late stage AIDS
- Actively dying
- Patient request
- Pill burden
- Drug side effects
- Drug interactions w. symptom drugs
3 palliative medications that can interact with HAART
- Dexamethasone (inducer)
- Haloperidol (inhibitor)
- Phenytoin
- All opioids
- Methadone especially
- TCAs
4 categories of rehabilitation
- Preventative
- Restorative
- Maintenance/Supportive
- Palliative
4 non-motor skills assessed by OT
- Sensory skills
- Cognitive skills
- Interpersonal skills
- Self-maintenance skills
- Work skills
- Leisure skills
4 ways to preserve energy with hygiene
- Chair in shower/bath
- Reach tools (e.g. sponge on a stick)
- Soap on a rope
- “Focal” bathing of axilla, face, perineum
- Bathtub/shower organisers
- Dry off using a thick robe
5 components of PPS
- Ambulation
- Activity
- Self-care
- Oral intake
- LOC
What is a 3-6 week survival tool? 5 components?
PPI
- PPS
- Dyspnea
- Delirium
- Edema
- Oral intake
What is a 30-day survival tool? 5 components?
- KPS
- Clinician estimate of survival
- Dyspnea
- Oral intake
- WBCs
- Lymphocyte %
NURSE model
Used to explore emotions with patients/families.
- Name the emotion
- Understand the emotion/express (partial) understanding
- Respect the person’s ability to cope with it
- Support them/offer support
- Explore
Legal documents for preferences of EOL or health care proxy?
Process of reflecting and communicating about future care?
Advanced directives
ACP
Brain death vs. PVS?
Brain Death
- complete loss cortical and brainstem functions
- no brainstem reflexes
PVS
- intact brainstem
4 strategies to improve communication with patients/families
- Be polite, punctual, mannerly
- Allow them to set the agenda
- Solicit questions
- Be direct and concrete
- Acknowledge your own limitations when giving answers
- Consistency in messaging from all staff
- Maintain continuity of communication on patient and provider side
- Give explicit examples of problematic behaviour
3 strategies to reduce intra-team conflict
- Allowing different opinions to exist
- Consistent channels for suggestions/complaints
- High standards for communication
- Deal with conflict as it arises–no ruminating
- Focusing on problems and solutions, not people
- Keep issues internal
3-stage process to conflict management
- Listen to understand the problems (all stakeholders)
- Explore and agree on a plan
- Enact the plan/follow up on everyone’s feelings
i.e. communicate, collaborate, check-in
List 4 of CSPCP’s goals
- Support CFPC (PC) certification
- Support RCSPM certification
- Support YAC programs
- Monitor/support adequate palliative practitioners
- Physician networking spaces
- Policy/advocacy for accessible PC
- Support ongoing CME for palliative care
CSPCP 5 strategic priorities
- Education
- Member engagement
- Infrastructure
- Research
- Advocacy/Partnerships
PRIME
Vision statement for CHPCA?
That all Canadians have access to quality hospice/palliative care.
8 questions to identify patient vulnerabilities?
- Do you have a stable place to live?
- Do you feel safe in your home/relationship?
- Can you read?
- Do you ever worry about where you will get your next meal?
- Who can you turn to in life for support?
- Do you ever have trouble paying utility bills?
- Do you read to your child at night?
- Have you ever neede to take out a restraining order?
- Do you have questions about your immigration status?
- Do you ever have trouble getting places? For instance, paying for public transit?
4 factors that influence “good death”
- Control
- Closure
- Comfort
- Companionship
- Circumstances of death
- Cultural norms respected
Characteristics of a study to benefit future (not current) patients?
How do you enhance these characteristics?
Validity
Value
Larger studies
Improve generalisability
4 risk factors for frailty
- Advanced age
- Multimorbidity
- Polypharmacy
- Sedentary lifestyle
- Weight loss
- Poverty
Name one clinical frailty tool and its components
Clinical Frailty Scale
- not actuarial
- 1-9 score, 9 being terminally ill
- 3 = not regularly active
- 6 = need help inside and outside home, incl. bathing
- 7 = total dependence but not dying
- 8 = total dependence and declining (“maximum frailty”)
- 9 = EOL <6mo regardless of frailty
3 negative outcomes associated w frailty
- Hospitalisation
- Early death
- Increased dependence
- Reduced QOL
2 possible pathogeneses of frailty
- Pro-inflammatory cytokines
- Cachexia-promoting gene activation
- Testosterone deficiency
- Vitamin D deficiency
3 markers of poor short-term survival in dementia
- Dysphagia/aspiration
- Pressure sores
- Weight loss
- Recurrent infections
4 factors that influence stroke outcomes
- Ischemic vs. hemorrhage
- Embolic vs. thrombotic
- Location
- Extent of damage
- Age
- Baseline health (function, comorbidities)
2 tools to measure neurological severity of a stroke
- Canadian Neurological Scale
- NIH Stroke Scale
2 causes of pain in stroke
- Central sensitisation
- Contractures
- Immobility/sores
- Shoulder-hand syndrome
PAINAD Scale–5 items + how long before using
Observe for 5+ minutes.
- Non-verbal vocalisations
- Grimace
- Consolability
- Body language
- Breathing
4 s/e of antipsychotic medication in BPSD
- Dystonia
- ANS instability (orthostasis)
- Sedation
- Premature death
- Hypercholesterolemia/T2DM
List the 3 qualities of dyspnea
- Air hunger
- Breathlessness/increased WOB
- Chest tightness
List 4 physical complications of cough
- Incontinence
- Rib #/chest wall pain
- Insomnia
- Muscle strain
What 2 features are necessary for a bony met to be seen on XR?
<1cm
<50% mineral loss
What feature is required for a met to show up on bone scan? Which cancers will they not show up on as easily?
Mineral deposition (i.e. element of sclerosis)
Aggressive sclerotic lesions
- thyroid
- aggressive lung
- myeloma
What % of malignant pathological # heal?
1/3 (35%)
List 3 cancers associated with osteoBLASTIC lesions
SCLC
Prostate
Medullablastoma
Hodkgin lymphoma
Carcinoid
List 3 cancers associated with osteoLYTIC lesions
NSCLC
Thyroid
Renal cell ca
NHL
List 3 cancers that metastasise to the hands/feet.
- Renal
- Esophagus
- NSCLC
List 3 cancers responsive to embolisation
- Thyroid
- RCC
- HCC
List 3 indications for nephrostomy placement in palliative care
- Malignant ureteric obstruction
- Hemorrhagic cystitis
- Radiation cystitis
- Urinary diversion from fistula
2 indications for IVC filter
- Anticoagulation contraindicated in lower limb DVT
- Free-floating IVC thrombus
What syndrome can follow arterial chemoembolisation of HCC?
“Postablation syndrome” d/t released necrotic tumour
- Fever
- Abdominal pain
- WBCs
- Malaise
Sustained fevers suggest abscess.
List 4 benefits of medical multidisciplinary teams
- Patient accessibility
- Reduced unplanned admissions
- Reduced length of stay
- Reduce spending
What are 3 core elements of evaluating an inpatient palliative care team
Organisation/Structure
- specific goals
- healthy work culture
- distinct roles within team
- distinct role of team
- adequate participatory leadership
- necessary services
Individual contributions
Team processes
List 4 roles the leader of a PC team must assume
- Management
- Conflict management
- Motivation
- Policy-setting
- Maintaining focus on vision
- PR
- Ongoing practice of palliative care