Questions from lecture

Question 1

T helper cells differentiation into different Th cells is determined by
a. cytokine environment
b. type of antigen
c. location of activation
d. all of the above
e. none of the above

Answer 1

d. all of the above

Question 2

which molecules are involved in macrophage cytotoxicity?
a. Fc receptors
b. TNF alpha
c. IgG
d. oxygen radicals
e. all of the above

Answer 2

e. all of the above

Question 3

the interaction of which two molecules is critical for the activation of naiive CD4 T cells?
a. MHC II/peptide: TCR
b. B7:CD28
c. IL-2:IL-2R
d. MHC II:CD4

Answer 3

B

Question 4

most exogenous antigens are processed by dendritic cells and presented to
a. CD4 T helper cells
b. CD8 T cytotoxic cells

Answer 4

a. CD4 T helper cells

Question 5

Which of the following is true of positive selection?
a. it occurs in bone marrow
b. it is responsible for maintaining self tolerance
c. it is responsible for maintaining HLA restriction
d. it occurs to Pre T cells who do not express alpha/beta TCRs

Answer 5

c

Question 6

Stem cells migrating to the thymus express this/these molecule(s) on their surface
a. CD3
b. CD3, CD4, CD8
c. CD4 and CD8
d. chemokine receptors
e. chemokine receptors and CD3

Answer 6

d

Question 7

The influenza vaccine contains dead virus particles. Antigens in this vaccine will most likely activate?
a. CD3CD8 cytotoxic T lymphocytes
b. CD16CD56 natural killer cells
c. CD3CD4 helper T cells

Answer 7

c

Question 8

which of the following MHC encoded molecules are responsible for presenting antigenic peptides that are derived from phagocytosis or endocytosis?
a. HLA class I
b. HLA class II
c. both HLA class I and II
d. neither HLA class I or II

Answer 8

b

Question 9

peptides generated within the cytosol of a host cell are likely to become associated with which of the following MHC encoded molecules?
a. HLA class I
b. HLA class II
c. both HLA class I and II
d. neither HLA class I or II

Answer 9

a

Question 10

if CLIP bound to MHC II irreversibly, what would happen?

Answer 10

no peptides would be presented

Question 11

which of the following associations is correct?
_____ presents ___ ag.
a. HLA-A exogenous
b. HLA-DQ exogenous
c. HLA-DP endogenous
d. HLA-C exogenous

Answer 11

b

Question 12

which of the following associations are correct?
____ presents ____ ag.
a. MHC I endogenous
b. MHC II endogenous
c. MHC I exogenous
d. MHC II exogenous

Answer 12

a and d

Question 13

can antibodies gain access to the intracellular environment?

Answer 13

no. it is the job of T lymphocyte system to recognize intracellular antigens