Questions Flashcards

1
Q

prograf

A
  • Increased risk of cancer
  • Increased risk of Infection
  • No grapefruit juice
  • Can cause high blood sugar, HTN, hyperkalemia, anemia, low phosphate levels
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2
Q

acute rejection

A

Sudden onset within days or months, typically beginning as hypersensitivy response. HLA antigens are recognized as being foreign, triggering immune response

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3
Q

acute rejection checking in heart

A

biopsy

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4
Q

know upper vs lower (active/nonactive)

A

Upper active= bright red blood emesis
upper not active= coffee grounds emesis
Lower= rectal bleeding for active, traces of blood or tarry stool for non

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5
Q

signs acute rejection in kidney

A

decreased urine output

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6
Q

Histocompatability antigens are also known as ?

  • Monocytes
  • Macrophages
  • Human leukocyte antigens
  • Ploymorphonuclear lymphocytes
A

Human leukocyte antigens

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7
Q

HLA antigens are located on (in) the cell?

  • Surfaces
  • Muclleus
  • Cytoplasm
  • Mitochondria
A

surfaces

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8
Q

The best histocompatability matching is found between?

  • Siblings
  • Identical twins
  • Parent-child
  • Fraternal twins
A

Identical twins

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9
Q

A recipient can beome sensitized to foreign HLA antigens through which of the following ways (Choose all that apply):

  • Pregnancy
  • Donating blood
  • Prior organ transplantation
  • Receiving blood transfusions
A

Pregnancy
Prior organ transplantation
Receiving blood transfusions

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10
Q

Which of the following are examples of technical complications of organ transplantation?

  • Bleeding
  • Infection
  • Anastomosis leakage
  • Vascular thrombosis
A

Bleeding
Anastomosis leakage
Vascular thrombosis

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11
Q

Organ rejection that takes place within minutes to hours following transplantation and results from the presence of preformed graft-specific cytotoxic antibodies is called ____ rejection?

  • Acute
  • Subacute
  • Chronic
  • hyperacute
A

hyperacute

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12
Q

Post-tranasplantation patients are at particular risk for developing a(n) infection wither from being seropositive prior to the transplant of by receiving a seropositive organ or blood transfusion.

  • Hepatitis A
  • Pneumonia
  • Cytomegalovirus
  • wound
A

cytomegalovirus

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13
Q

Post-transplant patients are at increased risk for development of malignancies secondary to _______.

  • Organ toxicity
  • Preexisting conditions
  • Underlying tissue incompatibility
  • Prolonged immunosuppressant therapy
A

prolonged immunosuppressant therapy

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14
Q

The immunosuppressant that selectively acts against helper T cells without affecting other types of immune cells is:

  • Corticosteroids
  • Azathioprine
  • Cyclosporine
  • OKT3
A

cyclosporin

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15
Q

Long term post-transplant steroid therapy is particularly associated with potentially severe _____ disorders.

  • Heart
  • Bone
  • Liver
  • blood
A

bone

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16
Q

The major gastrointestional side effect common to almost all immunosuppressant drugs is:

  • Nausea/ vomiting
  • Heartburn
  • Abdominal cramping
  • Constipation
A

Nausea/ vomiting

17
Q

The most common side effect associates with CRS is:

  • Chills
  • Vomiting
  • Diarrhea
  • Hypotension
A

Chills

18
Q

Postoperative management of the patient with a heart transplant includes the foal of preventing infection. Which of the following interventions most directly addresses this goal?

  • Early ambulation
  • Monitor urine output
  • Monitor ABG’s, pulse oximetry, and Svo2
  • Aggressive post extubation pulmonary toileting
A

Aggressive post extubation pulmonary toileting

19
Q

Postoperative monitoring of liver function typically includes which of the following (choose all that apply)?

  • Bilirubin
  • Ammonia
  • PTT
  • BUN
A
  • Bilirubin
  • Ammonia
  • PTT