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Biochemistry of Hormone > Questions > Flashcards

Questions Flashcards

1
Q

which option is not correct?

A)
Glucocorticoids : 21 carbon containing steroids and synthesized by zona glomerulosa,

B)
Mineralocorticoids: 21 carbon containing steroids and synthesized by zona glomerulosa,

C)
Glucocorticoids: Also 21 carbon steroids, produced mostly in zona fasciculata and affect glucose

D)
Androgens:The zona reticularis and fasciculata produce significant amounts of androgen precursor

A

A)
Glucocorticoids : 21 carbon containing steroids and synthesized by zona glomerulosa,

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2
Q

which hormone is not glycoprotein?

A)
FSH

B)
LH

C)
GH

D)
TRH

A

C)
GH

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3
Q

What is the SRIF?

A)
Somatostatin

B)
GHRIH

C)
None

D)
a+b

A

D)
a+b

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4
Q

Which option is not the effects adrenal corticosteroids on Lipid metabolism?

A)
Increase the utilization of FFA for TG synthesis

B)
Increase the free fatty acids in circulation

C)
Decrease the utilization of FFA for TG synthesis

D)
Increase the lipolysis in peripheral tissues

A

A)
Increase the utilization of FFA for TG synthesis

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5
Q

Which option is correct?

A)
Sex hormones are synthetized by Cortex of Adrenal ( reticular part ) and placenta

B)
Sex hormones are synthetized by testes and ovaries

C)
Sex hormones are steroids

D)
all

A

D)
all

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6
Q

What is the function of DUOX (THOX) in thyroid cells?

A)
Oxidation of iodine

B)
Hydrolysis of thyroglobulin

C)
Production of hydrogen peroxide

D)
Coupling of DIT and MIT

A

C)
Production of hydrogen peroxide

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7
Q

What is not the lydig cells function ?

A)
It synthesis the inhibin

B)
a+b

C)
Secret the testosterone

D)
It has receptor for LH

A

B)
a+b

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8
Q

Which Enzyme is necessary for estrogen synthesis?

A)
Kinase

B)
Aromatase

C)
All

D)
Phosphorylase

A

B)
Aromatase

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9
Q

Which protein is the main carrier for T3 and T4 in blood circulation?

A)
TTR

B)
Lipoproteins

C)
TBG

D)
Albumin

A

C)
TBG

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10
Q

Which option is correct?

A)
Secretion of TSH is by hypophysis

B)
Secretion of TSH is regulated by TRH

C)
All

D)
Secretion of TSH is regulated by T3, T4

A

C)
All

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11
Q

What is the precursor of the estrogene?

A)
all

B)
testosterone

C)
DHEA

D)
androstenedione

A

B)
testosterone

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12
Q

Which molecule effect will be antagonized by GH?

A)
Insulin effect

B)
all

C)
TRH effect

D)
PRH effect

A

A)
Insulin effect

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13
Q

Which enzyme is activated by insulin?

A)
Phosphoenolpyruvate carboxykinase

B)
Glucose 6-phosphatase

C)
Fructose 1,6 bis phosphatase

D)
Pyruvate kinase

A

D)
Pyruvate kinase

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14
Q

What is necessary for spermatozoid protection?

A)
Inhibin synthesis

B)
All

C)
ABG synthesis

D)
testosterone secretion

A

B)
All

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15
Q

Which statement is true about G-proteins?

A)
They become inactivated by binding of GTP

B)
They consist of two α and two β subunits

C)
They are activated in response to the binding of hormone to its receptor

D)
They are inactivated by the hydrolysis of ATP

A

C)
They are activated in response to the binding of hormone to its receptor

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16
Q

What is pheochromocytoma( PCC)?

A)
A neuroendocrine tumor of the medulla of the adrenal glands

B)
Extra-adrenal chromaffin tissue secretes excessive amounts of catecholamines

C)
a+b

D)
none

A

C)
a+b

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17
Q

Which tissue needs insulin for the uptake of glucose?

A)
Pancreas

B)
Muscle

C)
Liver

D)
Brain

A

B)
Muscle

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18
Q

What is the transporter of iodine in the apical membrane?

A)
Pendrin

B)
I2 ATPase

C)
NIS

D)
Na/K ATPase

A

A)
Pendrin

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19
Q

Which one is correct for catechol amines function?

A)
induces lipid hydrolysis

B)
All

C)
Induces protein hydrolysis

D)
Induces Glycogene hydrolysis

A

B)
All

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20
Q

What is the main progesterone metabolite?

A)
Pregnadiol

B)
none

C)
progestin

D)
Estriol

A

A)
Pregnadiol

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21
Q

Which option is not correct for Hypothalamus?

A)
It maintains the chemical and temperature homeostasis

B)
It inhibits the release of hormones from the anterior and posterior pituitary

C)
It Controls the release of hormones from the anterior and posterior pituitary

D)
It is responsible for the production of many of the body’s essential hormones, chemical substances that help control different cells and organs

A

B)
It inhibits the release of hormones from the anterior and posterior pituitary

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22
Q

Which one is not the mineralocorticoid function?

A)
Promotes synthesis of transport proteins (pumps)

B)
Reabsorb the K+, H+ and NH+4 ions

C)
Acts on all epithelial cells that exchange Na+ and water

D)
Excretion of K+, H+ and NH+4 ions in urine

A

B)
Reabsorb the K+, H+ and NH+4 ions

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23
Q

What the GnRH concentration in circulation is regulated by?

A)
Cortisol

B)
Sex hormones concentration

C)
PRH

D)
All option

A

B)
Sex hormones concentration

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24
Q

What is the estrogen function, at midcycle?

A)
Stimulating the pituitary to release LH and stop the secreting FSH

B)
Stopping the pituitary to release LH and stop the secreting FSH

C)
Stopping the pituitary to release LH and stimulating the secreting FSH

D)
Stimulating the pituitary to release LH and stimulating the secreting FSH

A

A) Stimulating the pituitary to release LH and stop the secreting FSH

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25
Q

The receptor of which hormone is found in the cell nucleus in the free and bound form?

A)
Adrenal hormones

B)
Pituitary hormones

C)
Pancreatic hormones

D)
Thyroid hormones

A

D)
Thyroid hormones

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26
Q

What does not regulate ACTH release?

A)
CRH

B)
Stress

C)
Hypoglycemia

D)
PRH

A

D)
PRH

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27
Q

Which option is correct Hypotalamus?

A)
production of many of the body’s essential hormones

B)
chemical substances

C)
help control different cells and organs

D)
All

A

D)
All

28
Q

Which statement is true about thyroid hormones?

A)
Their secretion is enhanced by lithium

B)
Their half life is about minutes

C)
They exert feedback inhibition both on TSH and TRH

D)
The concentration of T3 is more than T4

A

C)
They exert feedback inhibition both on TSH and TRH

29
Q

Which hormone is carried by binding protein?

A)
ACTH

B)
LH

C)
Insulin

D)
T3

A

D)
T3

30
Q

Which of the enzymes of the glycolysis pathway is the main enzyme regulated by both insulin and glucagon?

A)
Aldolase

B)
Phosphoenolpyruvate carboxy kinase

C)
Hexokinase

D)
Phosphofructo kinase

A

D)
Phosphofructo kinase

31
Q

Which hormne`s function is similar to dopamin?

A)
TRH

B)
PRH

C)
PRIH

D)
FSH

A

C)
PRIH

32
Q

Which statement is true about glucagon?

A)
Decreases the survival of pancreatic cells

B)
Increases gluconeogenesis in adipose tissue

C)
Decreases glycolysis in red blood cells.

D)
Decreases fatty acid synthesis in liver

A

D)
Decreases fatty acid synthesis in liver

33
Q

Which cells of testes has FSH receptor?

A)
Lydic cells

B)
Spermatogonia cells

C)
Sertoli cells

D)
All

A

C)
Sertoli cells

34
Q

Which enzyme is increased by insulin?

A)
Carnitine palmitoyl transferase 1

B)
Acetyl coA carboxylase

C)
Hormone sensitive lipase

D)
Protein kinase A

A

B)
Acetyl coA carboxylase

35
Q

Which hormone is diabetogenic?

A)
Cortisol

B)
PRH

C)
GH

D)
FSH

A

B)
PRH

36
Q

What is liver metabolic functions of adrenocorticosteroids for protein?

A)
Catabolysis

B)
Synthesis

C)
More Synthesise and less cathobolisis

D)
Less Synthesise and more cathobolisis

A

B)
Synthesis

37
Q

Which metabolic procedure is decreased by thyroid hormones?

A)
Glycolysis

B)
Lipogenesis

C)
Glycogenolysis

D)
Protein hydrolysis

A

B)
Lipogenesis

38
Q

What is the main target for Hypotalamus hormones?

A)
anterior Pituitary

B)
Posterior Pituitary

C)
Pituitary

D)
Liver

A

C)
Pituitary

39
Q

How the Na+ and water movement is facilitated across kidney cell membrane?

A)
By active transporter of proteins (pumps) function

B)
By Mineralocorticoid hormones mediation

C)
By reabsorption of sodium by the distal convoluted tubules of kidney.

D)
All

A

D)
All

40
Q

Which compound competes with iodine in the trapping stage?

A)
Pertechnetate

B)
Selenium

C)
Sodium

D)
chlorine

A

A)
Pertechnetate

41
Q

Which function is not correct for estrogen?

A)
It increases in adipose (fat) tissue

B)
It decreases in adipose (fat) tissue

C)
No affect on adipose tissue

D)
Promotes the blood clotting

A

B)
It decreases in adipose (fat) tissue

42
Q

What is PRL target?

A)
Breast

B)
Testes

C)
ovary

D)
all

A

D)
all

43
Q

Which option is not correctduring carbohydrate intake?

A)
GH antagonizes the insulin effects

B)
GH agonizes the insulin effects

C)
GGH blocksthe glucose uptake

D)
Prevent hypoglycemia

A

B)
GH agonizes the insulin effects

44
Q

Which hormone is nor corticosteroid?

A)
aortisol

B)
Aldestrone

C)
DHEA

D)
Adrenalin

A

D)
Adrenalin

45
Q

Which organ is the main organ for progesterone Up take from circulation?

A)
Ovary

B)
liver

C)
testis

D)
None

A

B)
liver

46
Q

How the Hypothalamus Hormones will be inactivated?

A)
By lysosomal hydrolysing

B)
By deletion of pyroglutamic acid at C terminal of hormones

C)
By deletion of pyroglutamic acid atNterminal of hormones

D)
a+b

A
47
Q

How the Hypothalamus Hormones will be inactivated?

A)
By lysosomal hydrolysing

B)
By deletion of pyroglutamic acid at C-terminal of hormones

C)
By deletion of pyroglutamic acid at N-terminal of hormones

D)
a+b

A

D)
a+b

48
Q

What is the main estrogen hormones?

A)
17 β estradiol and

B)
Estron

C)
Estriol

D)
b+c

A

D)
b+c

estrone (E1), estradiol (E2), and estriol (E3)

49
Q

What is the GnRH function?

A)
It inhibits the FSH synthesis by pituitary

B)
It inhibits the LH synthesis by pituitary

C)
It stimulates the FSH synthesis by pituitary

D)
It stimulates the FSH synthesis byhypothalamus

A

C)
It stimulates the FSH synthesis by pituitary

50
Q

Which enzyme is activated by glucagon?

A)
Glucose 6 phosphatase

B)
Hexokinase

C)
Pyruvate kinase

D)
enolase

A

A)
Glucose 6 phosphatase

51
Q

What is the activity of type 1 deiodinase?

A)
Removal of 3’ iodine

B)
Removal of 5’ iodine

C)
Removal of 5 iodine

D)
Removal of either 5 or 5’ iodine

A

D)
Removal of either 5 or 5’ iodine

52
Q

Which enzyme is activated by Gαs protein?

A)
Guanylyl cyclase

B)
Adenylyl cyclase

C)
Tyrosine kinase

D)
JAK

A

B)
Adenylyl cyclase

53
Q

Which one is the main carrier protein for thyroid hormones?

A)
Albumin

B)
Lipoproteins

C)
transthyretin (TTR)

D)
thyroxine-binding globulin (TBG)

A

D)
thyroxine-binding globulin (TBG)

54
Q

Which pathway is enhanced by insulin?

A)
Fatty acid oxidation

B)
Fatty acid synthesis

C)
Glycogenolysis

D)
Ketone body production

A

B)
Fatty acid synthesis

55
Q

Which protein is responsible for transport of thyroid hormones from the thyroid cells into the colloid?

A)
NIS

B)
Na/K ATPase

C)
pendrin

D)
megalin

A

C)
pendrin

56
Q

What is the effects of adrenocorticosteroids on Protein metabolismin extra hepatic tissues?

A)
No effect

B)
Degradation of proteins

C)
Synthesis of proteins

D)
Both degradation and synthesis

A

B)
Degradation of proteins

57
Q

Which one is not glycoprotein?

A)
TSH

B)
ACTH

C)
LH

D)
FSH

A

B)
ACTH

58
Q

The receptor of which hormone exists in the cell membrane?

A)
Thyroid hormones

B)
Progesterone

C)
Testeosterone

D)
Prolactin

A

D)
Prolactin

59
Q

Androgen-binding protein (ABP) is synthesized by the ……………. in the testis

A

Sertoli cell

60
Q

Hypoglycemia is a potent ……………..for the release of serum GH and cortisol.

A

stimulus

61
Q

The TRH stimulation test is used to check for ……………..

A

PRH

62
Q

Adrenal androgens (AA) are …………………steroids that are secreted by the adrenal cortex through complicated biosynthetic pathways.

how many carbons?

A

19 carbon (C19)

63
Q

pyroglutamic acid in found on…………………… hormone structure

A

thalamus

64
Q

Dehydroepiandrosterone (DHEA) is a hormone that your body naturally produces in the ………… .
Dehydroepiandrosterone (DHEA) is thought to be an anti-glucocorticoid hormone.

A

adrenal gland

65
Q

Dehydroepiandrosterone (DHEA) is a steroid hormone that serves as a precursor to ………………….. in men and ……………… in women.

A

androgens (testosterone) - estrogens

66
Q

Glucocorticoids ……………………. antidiuretic hormone (ADH) secretion.

A

suppress

Biochemistry of Hormone (1 decks)

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