Questions Flashcards
what stimulates the T cell response in vaccines?
proteins
(toxoid allows for additional T response)
what part of the spleen removes RBC membrane
red pulp (cords of bilroth)
asplenic patients are at an increased risk for infection from pathogens that infect ___
RBCs
___ ___ occurs in lymphoid follicles
class switching
subacute penicillin allergic reaction is a type ___ HSR
III (immune complex)
HSR 6 hours after insulin injection
type III
cryoglobinemia is a type ___ HSR
III
WBC casts indicate ___ ___
interstitial nephritis
immunosuppressant that causes nephrotoxicity and HTN
cyclosporine
what is the effect of mTOR inhibition
cytokine responses are blocked
mycophenolic acid inhibits ___ ___
IMP dehydrogenase
anti-citrulline AB are specific for ___
RA
felty syndrome is RA, splenomegaly, and ___
neutropenia
anti-___ ___ ___ AB increase the risk for scleroderma renal crisis
RNA polymerase III
neonatal complete heart block is a complication for mothers with what?
AI disorders
proteinase-3 = ___
c-ANCA
somatic mosaicism is a ___ error
mitotic
dystrophin binds to ___
actin
myotonic dystrophy is due to an abnormal ___ ___
protein kinase
myotonic dystrophy features ___
cataracts
williams syndrome is a defect in ___ synthesis
elastin
___ levels are high in williams syndrome
Ca
A1AT deficiency expresses ___ inheritance
codominant
different effects in different organs exemplifies ___
pleiotropy
pityriasis rosea is due to a(n) ___ infection
viral (HHV8)
vitiligo is associated with an increased risk for ___ ___ disease
AI thyroid
erisypelas is located in the upper ___
dermis
bullous pemphigoid includes what WBC?
eosinophils
SJS is a type ___ HSR
4
sturge-weber inheritance
spontaneous (0%)
giant cell astrocytomas are associated with ___
TS
VHL mutations prevent what process from occurring?
ubiquitination
