QUANTEC

Question 1

Small bowel

Answer 1

Volume receiving 45Gy should be less 195cc to create a less than 10% chance of obstruction/bleeding requiring surgery

Question 2

Bladder

Answer 2

Max. dose of 65Gy to whole organ creates a less than 6% chance of frequent dysuria &generalised telangiectasia, frequent haematuria & decrease in bladder capacity (<150ml)

Question 3

Rectum

Answer 3

V50<50%
V60<35%
V65<25%
Less than 10% chance of moderate diarrhoea, excessive rectal mucous, intermittent bleeding & obstruction or bleeding requiring surgery

Question 4

Testes

Answer 4

The volume receiving 50Gy should be less than 90% to create a less than 35% chance of severe erectile dysfunction months to years post RT (penile bulb)

Question 5

Stomach

Answer 5

45Gy to the whole organ creates a less than 7% chance of ulceration, mucosal erosion & perforation months to years post RT

Question 6

Kidneys

Answer 6

The volume receiving 28Gy should be less than 20% to create a less than 5% chance of dysfunction, nephritis & kidney failure months to years post treatment

Question 7

Spinal cord

Answer 7

Max. dose of 50Gy to part of the organ creates a less than 0.2% chance myelitis necrosis months to years post RT

Question 8

Heart

Answer 8

The volume receiving 25Gy should be less than 10% (whole heart) to create a less than 1% chance of long-term cardiac mortality months to years post treatment

Question 9

Lung

Answer 9

The volume receiving 20Gy should be less than or equal to 30% (combined lungs) to create a less than 20% chance of symptomatic pneumonitis

Question 10

Larynx

Answer 10

Max. dose of less than 66Gy within the organ creates a less than 20% chance of vocal dysfunction months post RT

Question 11

Parotid

Answer 11

Bilateral Whole = mean dose of less than 25Gy creates a less than 20% chance of long-term salivary function of less than 25%
Unilateral Whole = mean dose of less than 20Gy creates a less than 20% chance of long-term salivary function in the effected parotid of less than 25%

Question 12

Brain

Answer 12

Max. dose of less than 60Gy within the brain creates a less than 3% chance of symptomatic necrosis months to years post RT

Question 13

Brain Stem

Answer 13

Max. dose of 54Gy within the whole organ creates a less than 5% chance of neuropathy & necrosis months to years post RT

Question 14

Optic Nerve

Answer 14

Max. dose of less than 55Gy within the organ creates a less than 3% chance of optic neuropathy (leading to blindness) months to years post RT

Question 15

Optic Chiasm

Answer 15

Max. dose of less than 55Gy within the organ creates a less than 3% chance of optic neuropathy leading to blindness in both eyes months to years post RT