Qs Flashcards

1
Q

A 52-year-old woman attends for a discussion regarding her recent diagnosis of bladder cancer. Her hospital discharge letter comments that histology has confirmed carcinoma in situ.

In addition to transurethral resection of bladder tumour (TURBT), what further treatment is the SINGLE MOST likely to be offered to this patient? Select ONE option only.

Select one:
A.Intravesical Bacillus Calmette–Guérin (BCG)
B.Intravesical chemotherapy
C.No further treatment
D.Radiotherapy
E.Annual monitoring
A

ANS A.

Answer justification and feedback: Carcinoma in situ (CIS) is a superficial tumour, but it has strong potential to become muscle-invasive so is treated differently to less aggressive superficial tumours. Maintenance therapy with intravesical Bacillus Calmette–Guérin (BCG) should be considered to improve local control and reduce the incidence of progression.
Resource:
NICE.Bladder cancer: diagnosis and management(NG 2).2015.

The correct answer is: Intravesical Bacillus Calmette–Guérin (BCG)

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2
Q

A 78-year-old patient attends with a gift following your recent prompt referral for his acute myocardial infarction.
According to the NHS England Standard GMS Contract, what is the threshold at which gifts should be recorded in a register? Select ONE option only.

Select one:
A.£10
B.£25
C.£100
D.£250
E.£50
A

Answer justification and feedback:This raises ethical issues around the impact of potential or actual gifts on the objectivity and professionalism of the doctor–patient relationship. The GMC’sGood Medial Practiceguidelines state that:

  • You must not encourage patients to give, lend or bequeath money or gifts that will directly or indirectly benefit you
  • You must not put pressure on patients or their families to make donations to other people or organisations.

The NHS England Standard GMS Contractrequires individual GPs and contractors to keep a register of gifts from patients or their relatives which have a value of £100 or more unless the gift is unconnected with the provision of services.

Resources:

BMA.Receiving gifts from patients.2020.

GMC.Good Medical Practice.2013 (updated 2014, 2019).

The correct answer is: £100

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3
Q

A 45-year-old man has a booked telephone consultation with you. He has already self-certified for the first week off work and asks for a ‘fit note’ stating that he is unfit to work, back-dated a week and for four months duration. He tells you that he sustained a nasty fracture of his leg a week ago and was told by the hospital consultant that he would not be fit to work for at least four months. You check his notes and find a discharge summary relating to this injury.
In these circumstances, which of the following actions would be the SINGLE MOST appropriate? Select ONE option only.

Select one:

A.

Issue a fit note back-dated to a week from the date of the injury for a period shorter than three months

B.

Issue a fit note from the date of your consultation for a period shorter than three months

C.

Refuse to issue a fit note on the basis that the man has not been seen by you following his injury

D.

Issue a fit note back-dated to the date of the injury for a period of four months

E.

Issue a fit note from the date of your consultation for four months duration

A

Answer justification and feedback:The Statement of Fitness to Work or ‘fit note’ gives medical evidence of an individual’s fitness to work. It is intended for periods of absence from work for more than seven days (including weekends). For shorter periods, workers can self-certify their incapacity.
Before a ‘fit note’ can be issued, some form of assessment of the patient by a healthcare professional must have taken place. Therefore, forward-dated fit notes should never be issued. The assessment can take the form of a GP consultation (face-to-face or telephone) but written reports from other healthcare professionals are also allowable.
So, if a patient who has had a viral illness for two weeks without consulting a healthcare professional calls the GP and asks for a back-dated fit note to cover that period, a fit note should not be issued as there is no independent corroborating evidence of the illness. In this case, a written report is available from the treating hospital. This provides corroborating evidence for the patient and therefore a back-dated fit note to the date of this hospital assessment can be issued.
In the first six months of a patient’s condition, a ‘fit note’ can cover a maximum of three months. If a condition has lasted longer than six months, a fit note can be for any clinically appropriate period up to ‘an indefinite period’. The dates are inclusive, so a fit note dated from 24May to 3June will no longer apply from 4June onwards.
In this case, depending on the work that the man does and his progress towards recovery from his injury, he might be fit to return to work with suitable workplace adaptations well before 4 months. Therefore, good practice would be to issue a fit note stating that this man is unfit to work now, backdated to the date of his injury, and for a duration of less than three months with an endorsement on the form to state that you need to assess the man again before return to work.
Of note, a person can return to work at any point that he or she feels able to, even if this is before the expiry date of a fit note. There is no requirement to see the GP in order to return to work or for the GP to issue a further fit note to that effect.
Resource:
DWP.Fit note: guidance for GPs.

The correct answer is: Issue a fit note back-dated to a week from the date of the injury for a period shorter than three months

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4
Q

You see a 42-year-old man who has been asked to attend your afternoon surgery by your practice nurse following a routine diabetic review. She is concerned that he may be depressed and has asked him to complete a patient health questionnaire (PHQ-9). He has no previous history of psychiatric illness. His PHQ-9 score is 6.
What is the SINGLE MOST appropriate management for this patient? Select ONE option only

Select one:

A.

St John’s wort

B.

Fluoxetine

C.

Routine referral to a psychiatrist

D.

Amitriptyline

E.

Computerised cognitive behavioural therapy (CCBT)

A

Answer justification and feedback:Depression severity can be graded using the PHQ-9 score:

0–4 None

5–9 mild

10–14 moderate

15–19 moderately severe

20–27 severe

Consider offering one or more of the following low-intensity psychosocial interventions to patients with persistent subthreshold depressive symptoms or mild to moderate depression, and to patients with subthreshold depressive symptoms that complicate the care of their chronic physical health problem:

A physical activity programme (modified for the particular physical health problem)

A peer support programme in a group of patients with a shared physical health problem

Individual guided self-help based on cognitive behavioural therapy (CBT) principles

Computerised cognitive behavioural therapy (CCBT)

Watchful waiting is an option as a management strategy in selected patients with mild depression.
Do not use antidepressants routinely to treat subthreshold depressive symptoms or mild depression, but consider them for patients with one of the following:

A past history of moderate or severe depression

Mild depression that complicates the care of the physical health problem

Initial presentation of subthreshold depressive symptoms present for at least two years

Subthreshold depressive symptoms

Mild depression persisting after other interventions

The correct answer is: Computerised cognitive behavioural therapy (CCBT)

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5
Q

A 19-year-old patient with recurrent sore throat requests antibiotics unnecessarily. The consultation becomes very difficult. You consider using a consultation model to help deal with the consultation.
Which option is the SINGLE MOST appropriate? Select ONE option only.

Select one:

A.

Cambridge–Calgary model

B.

Helman–Folk Model

C.

The FRAYED model

D.

Transactional analysis

E.

DR SAMOSA

A

ANS C.

Answer justification and feedback:The FRAYED consultation model is for situations when doctors deal with what might be considered unreasonable demands from difficult patients. One aim of this model is to preserve the GP’s emotional health for the rest of the day's work. It is represented by the mnemonic FRAYED.
F– Fact-Finding
R– Refuse Request
A– Acceptable Alternative
Y– Yield or don’t Yield
E– End the Encounter
D– Document Diligently 

Resource:
Mirza D.The need for new GP consultation models.InnovAiT2018;12(1):33–37.
The correct answer is: The FRAYED model

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6
Q

Michael Balint was a psychologist whose work is still appreciated within general practice today.

What is an underlying principle in his work? Select ONE option only.
Select one:
A.A doctor’s behaviour and personality can impact on the doctor–patient relationship
B.Consultation is a ‘game’ of social interchange
C.Communication is initiated by the sender and interpreted by the receiver
D.Doctors are like drugs without side effects
E.Illness has a social meaning and is derived from a patient’s perspective

A

ANS A.

Answer justification and feedback:Balint introduced a pioneering approach to consulting in general practice. His work with other doctors highlighted the idea of the doctor as a ‘drug’ and suggested that doctors’ feelings have a function and can guide the direction of the consultation.

Resource:
Neighbour R.Challenging consultations.InnovAiT2018;12(1):24–29.
The correct answer is: A doctor’s behaviour and personality can impact on the doctor–patient relationship

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7
Q

Whilst practicing for the clinical skills assessment (CSA) it can be helpful to look at different consultation models.

Which of the following models adopts an evidence-based approach with a structure that includes information gathering, building the relationship and explanation/ planning?Select ONE option only.

Select one:
A.Pendleton’s 1984 model
B.Cambridge–Calgary model
C.Roger Neighbour’s 1987 model
D.Murtagh’s 1998 model
E.Stott and Davies’s 1979 model
A

ANS B.

Answer justification and feedback:The Calgary–Cambridge system can be used to understand the structure of the consultation and also includes initiating the consultation, building the relationship and closing the consultation. Murtagh’s model introduces the concept of uncertainty about the diagnosis and what conditions might be missed. Pendleton’s model combines structure with a psychodynamic element introducing enquiry about ideas, concerns and expectations. Roger Neighbour’s model includes the concepts of summarising, safety-netting and housekeeping. Stott and Davies introduced four key consultation tasks including modification of health seeking behavior, management of continuing problems and opportunistic health promotion.
The correct answer is: Cambridge–Calgary model

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8
Q
A 38-year-old man has had low back pain for five years and investigations have been normal. He and his family have been attending joint consultations with a member of the mental health care team in order to find solutions to his problems.
Which of the following BEST describes this therapeutic approach? Select ONE option only.
Select one:
A.Collaborative care
B.Cognitive behavioural therapy
C.Reattribution
D.Psychodynamic therapy
E.Brief intervention therapy
A

ANS A.

Answer justification and feedback:Collaborative care usually includes working with the patient and their family to define solutions to problems. Collaborative care studies have shown improvement both in symptoms and in health care utilisation costs for patients with medically unexplained symptoms (MUS).

Brief intervention therapy isdesigned to motivate individuals with unhealthy behaviours such as smoking, alcohol and substance misuse to alter their behaviour. It ofteninvolves using validated tools ( e.g theAlcohol Use Disorders Identification Test(AUDIT)) to screen and identify those at risk.

Cognitive behavioural therapy (CBT) is a form of psychological treatment that has been demonstrated to be effective for a range of problems including depression and anxiety.

Reattribution isa technique which tests the thoughts and assumptions by considering alternative causes of events. This particularly helps to challenge beliefs held by people who perceive themselves as the cause of problem events.

Psychodynamic therapy draws on theories and practices of analytical psychology and psychoanalysis. It is a therapeutic process which helps patients understand and resolve their problems,helping individuals to unravel, experience and understand their true, deep-rooted feelings in order to resolve them.
The correct answer is: Collaborative care

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9
Q

A 31-year-old female retail manager comes to your morning surgery complaining of tiredness for about six weeks. She says she has been promoted in her job and reports no stress in her family life. She used to smoke 2–3 cigarettes a day for ten years, but gave up two years ago. She does not think she has lost weight and cannot recall any recent infection, abnormal bleeding, regular periods, cough or dyspnoea. She considers herself fit and healthy but this continued fatigue is bothering her. Her physical examination is unremarkable: temperature 36.4°C, blood pressure 128/72 mmHg, pulse 76 beats/min and regular.
What is the SINGLE MOST appropriate next step? Select ONE option only.

Select one:

A.

Perform further investigations in primary care

B.

Arrange review in 2–3 weeks and investigate further if no better

C.

Tell the patient to come back in a month if no better

D.

Do not investigate further and reassure the patient

E.

Refer the patient to the local chronic fatigue specialist service.

A

Answer justification and feedback:It would be advisable to offer first-line investigation in this case to exclude any underlying causes especially as this woman’s symptoms have been present for more than a month. First-line tests would include blood tests for full blood count, erythrocyte sedimentation rate or C-reactive protein, liver function tests, renal function tests, thyroid function, random blood glucose/glycosylated haemoglobin (HbA1c) andimmunoglobulin A (IgA) tissue transglutaminase.
Depending on additional factors and the individual presentation, it may also be worthwhile to consider checking bone biochemistry, ferritin, vitamin D level,human immunodeficiency virus(HIV),hepatitis serology and a chest X-ray.
Resource:
NICE.Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (or Encephalopathy): diagnosis and management(CG53).2007.

The correct answer is: Perform further investigations in primary care

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10
Q

Answer justification and feedback:It would be advisable to offer first-line investigation in this case to exclude any underlying causes especially as this woman’s symptoms have been present for more than a month. First-line tests would include blood tests for full blood count, erythrocyte sedimentation rate or C-reactive protein, liver function tests, renal function tests, thyroid function, random blood glucose/glycosylated haemoglobin (HbA1c) andimmunoglobulin A (IgA) tissue transglutaminase.
Depending on additional factors and the individual presentation, it may also be worthwhile to consider checking bone biochemistry, ferritin, vitamin D level,human immunodeficiency virus(HIV),hepatitis serology and a chest X-ray.
Resource:
NICE.Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (or Encephalopathy): diagnosis and management(CG53).2007.

The correct answer is: Perform further investigations in primary care

A

https://rcgp.eaction.org.uk/GPactionplan

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11
Q

Which one of the following BEST describes the use of illness narratives in medically unexplained symptoms?
Select one option only.

A. Facilitates pt involvement in record keeping
B. Guides use of investigations
C. Helps prevent litigation
D. Links the cultural background to a patient’s presenting symptoms
E. Supports joint record keeping with the family

😉

A

Hmm
I chose C
But RCGP says D is correct answer

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12
Q

You’re working a weekend shift for OOH service and are called to visit a 51 year old woman who was found dead in her bed an hour ago.
The husband reports that she was seen by her own GP for an annual Diabetic check six months ago.
You confirm the death and speak to husband.
Single most appropriate next step?

A. Contact the Coroner’s office
B. Contact the on call social worker 
C. Contact the funeral director 
D. Contact the police 
E. Call an ambulance
A

D

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13
Q
A 65 year old man attends your clinic complaining of a 4 month history of difficulty swallowing, episodes of staring and falls. 
What is the most likely diagnosis ?
A. Wilson's
B. Corticobasal ganglionic degeration 
C. Parkinson's 
D. Multiple System Atrophy 
E. Progressive Supranuclear Palsy
A

PSP (Steele-Richardson-Olszewski Syndrome)

  • Early Dysphagia
  • Gaze Palsy
  • Recurrent falls.
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14
Q

So the age 25-65(ideally 24.5-64).
3 yearly for 25-49, 5yearly for 50-64.
If >/=65 can still be screened of recent prior test was positive.
Pregnant women should have smears delayed till 12 weeks post partum, but in them colposcopy should not be delayed.

If smear shows positive Hr HPV, and abnormal cytology then refer for colposcopy.
If HrHPV positive, but negative cytology , repeat in 12 months, if negative HrHPV , then can return to routine, if positive HrHPV then repeat in smear in another 12 months, if negative for HrHPV then return to routine If positive for HrHPV (i.e at 24 months) irrespective of cytology should be referred for colposcopy.

Hmmmmmm what else

A

Age is now 24.5 to 65

Yes pregnancy 12 weeks

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15
Q

The ‘Blue Badge scheme’ allows people with severe mobility problems to park for free. This means badge holders can park close to where they need to go.

Which ONE of the following patients would be eligible for a Blue Badge automatically without the need for a further assessment? Select ONE option only.
Select one:
A.A 69-year-old man who receives a war pensioner’s mobility supplement
B.A 67-year-old woman who receives attendance allowance
C.A 71-year-old woman who has heart failure
D.A 19-year-old man who has cerebral palsy
E.A 37-year-old woman who receives incapacity benefit

A

ANS A.

Answer justification and feedback:The Blue Badge scheme is to help disabled people who have severe mobility problems to access goods, services and other facilities by allowing them to park close to their destination.

People automatically qualify for a badge if they are over two years old and meet at least one of the following criteria:
• Receiving the Higher Rate of the Mobility Component of the Disability Living Allowance
• Receiving a Personal Independence Payment for being unable to walk further than 50 metres (a score of 8 points or more under the ‘moving around’ activity of the mobility component)
• Registered blind (severely sight impaired)
• Receiving a War Pensioner’s Mobility Supplement
• Has received a lump sum benefit within tariff levels 1-8 of the Armed Forces and Reserve Forces (Compensation) Scheme and has been certified as having a permanent and substantial disability which causes inability to walk or very considerable difficulty in walking.

Other conditionsmay also be eligible for a badge if those affected can demonstrate that they have a permanent and substantial disability which causes inability to walk or very considerable difficulty in walking.The local authority is responsible assessing eligibility and may ask those applying for a Blue Badge to undergo a mobility assessment with a medical professional such as a physiotherapist or occupational therapist.
Resource:
Department for Transport.Blue Badge scheme.
The correct answer is: A 69-year-old man who receives a war pensioner’s mobility supplement

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16
Q

…………………………….
A 60-year-old patient withchronic obstructive pulmonary disease(COPD) started smoking when he was 20 and smoked 60 cigarettes a day until he was 40. At that time the duty on cigarettes went up and he cut back to 30 cigarettes a day, a habit that he still follows.
How many pack years has he smoked? Select ONE option only.

Select one:

A.

40 pack years

B.

60 pack years

C.

75 pack years

D.

90 pack years

E.

100 pack years

A

Answer justification and feedback:Pack yearsare calculated by dividing the number of cigarettes smoked per day by 20, then multiply by the number of years smoked.
He smoked 60 cigarettes divided by 20 = 3. This is for 20 years = 60
Then he cut down to 30 daily, divided by 20= 1.5. This for 20 years= 30
Therefore the total pack years for this man is 90
An up-to-date smoking history, including pack years smoked, should be documented for everyone with COPD.

The correct answer is: 90 pack years

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17
Q
Which TWO of the following are the MOST APPROPRIATE first-line medications for the relief of muscle spasticity in multiple sclerosis (MS)? Select TWO options only.
Select one or more:
A.Baclofen
B.Cannabis extract (sativex)
C.Dantrolene
D.Diazepam
E.Gabapentin
A

ANS A and E
Answer justification and feedback: Either gabapentin or baclofen are recommended by the National Institute of Clinical Excellence (NICE) as first-line treatments. If neither are effective alone or in combination, then tizanidine or dantrolene as second-line choices and benzodiazepines are third-line. Sativex is not cost effective.

Resource:
NICE.Multiple sclerosis in adults: management.2014 (updated 2019)
The correct answers are: Baclofen, Gabapentin

.

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18
Q
A 55 year old Male has tried gabapentin, pregabalin, amitriptyline and capsaicin cream for DM neuropathic pain with no success. He has asked you to try a different medication today. Which one of the following is Most appropriate to try next ?
A. Tramadol
B. Nortryptiline 
C. Co-codamaol 
D. Naproxen 
E. Duloxetine
A

Yes E.

NB all the other medication they had tried in the stem question are liscenced for DM neuropathic pain

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19
Q
Which medication below is safe in a G6PD patient?
A. Ciprofloxacin 
B. Primaquine 
C. Sulphasalazine 
D. Glicazide 
E. Phenoxymethylpenicillin
A

E.

All the others can trigger hemolysis in G6PD

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20
Q
A 74 year old long term smoker presents to his Gp with shortness of breath and haemptysis. On examination he is noted to have hyperpigmentation of his oral mucosa, palms and soles. Investigations reveal that he is diabetic and hypokalemic.
What is the most likely diagnosis? 
A. Conn's syndrome 
B. Addison's 
C. Ectopic ACTH 
D. Pseudocushing's syndrome 
E. Hypothyroidism
A

ANS C. he’s got likely lung Ca

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21
Q

A 50 year old Male diagnosed with Cushing’s disease.
What is the most common cause of Cushing’s disease?
A. Pancreatic NET
B. Phaechromocttoma
C. Pituitary adenoma
D. Adrenal adenoma
E. Adrenal hyperplasia

A

C.

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22
Q
A 55 year old Male has tried gabapentin, pregabalin, amitriptyline and capsaicin cream for DM neuropathic pain with no success. He has asked you to try a different medication today. Which one of the following is Most appropriate to try next ?
A. Tramadol
B. Nortryptiline 
C. Co-codamaol 
D. Naproxen 
E. Duloxetine
A

Yes E.

NB all the other medication they had tried in the stem question are liscenced for DM neuropathic pain

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23
Q
Which medication below is safe in a G6PD patient?
A. Ciprofloxacin 
B. Primaquine 
C. Sulphasalazine 
D. Glicazide 
E. Phenoxymethylpenicillin
A

E.

All the others can trigger hemolysis in G6PD

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24
Q
A 74 year old long term smoker presents to his Gp with shortness of breath and haemptysis. On examination he is noted to have hyperpigmentation of his oral mucosa, palms and soles. Investigations reveal that he is diabetic and hypokalemic.
What is the most likely diagnosis? 
A. Conn's syndrome 
B. Addison's 
C. Ectopic ACTH 
D. Pseudocushing's syndrome 
E. Hypothyroidism
A

ANS C. he’s got likely lung Ca

25
Q
A 62 year old woman, who us overweight and has mild learning difficulties , is discovered to have hypercalcemia. She takes metformin for DM and you note that she has short stature, a round 'moon face' and the 3rd and 5th  fingers of both of her hands are shortened. Her PTH levels are measured and found ronbe high. 
What is the most likely diagnosis 
A. Pseudohyperparthyroidism
B. Primary hyperparathyroidism 
C. Primary hyperparathyroidism 
D. Pseudohypoparathyroidsm 
E. Secondary hypoparathyroidism
A

Ans D.

26
Q
Which biochemical feature will you *NOT* expect in Addison's 
A. Hyoerkalaemia 
B. Hyponatremia 
C. Hypercalcemia 
D. High ACTH levels
E. Low serum renin
A

E

27
Q

A 44 year old type 2 diabetic man attends your clinic following a severe hypoglycemic event whilst awake. His wife had to give him a sugary drink to reverse it. You note from his records that he is only on metformin. He informs you that he is a Group 1 driver only and had driven here today.
What is the correct advice to give this man ?
A. Stop driving immediately and inform DVLA
B. Reapply for his driving license
C. Continue driving unless another hypoglycemic event occur
D. Stop metformin
E. Stop driving for 7 days and if he remains well he can restart.

A

C

28
Q

A 40 year old attends your clinic with a 12 week history of tiredness and joint pains. On examination you noticed increased pigmentation of the mucous membrane. You also noticed blood test done last week showed:
K+ 5.8
Na. 128

Which test should be offered to CONFIRM the diagnosis

A. HBA1C 
B. Rheumatoid Scree
C Synacthen Test 
D. Overnight Dexamethasone suppression test 
E. Thyroid function test
A

C Qs posted on 26/08

29
Q

A 29-year-old woman comes in to see you as she had sex with her boyfriend yesterday evening, however the condom split. She is currently on day 14 of her 28 day cycle. She says that she was previously on the combined oral contraceptive pill, but it ran out 2 months ago and she has not had time to get a repeat prescription.

She would like to have some emergency contraception today and then restart her combined oral contraceptive pill as soon as possible.

Which one of the following would you advise?

Take EllaOne today, start combined pill in 5 days time and use condoms for the next 12 days
Take EllaOne today, start combined pill tomorrow and use condoms for the next 7 days
Take EllaOne today, start combined pill immediately and use condoms for the next 5 days
Take EllaOne today, start combined pill in 5 days time and use condoms for the next 5 days
Take EllaOne today, wait until next period to start combined pill and use condoms until the next period

A

Ans is A.

Although no clear explqination given. And I cant figue out 12 days thing. If nyone can explain ?

30
Q

The following results have been obtained by your nurse at the respiratory clinic in the practice. All are male, non smokers.

Match each patient to the SINGLE MOST likely diagnostic option. Each option may be used once, more than once, or not at all.

Patient 1: Forced expiratory volume in one second(FEV1) 70% predicted, forced vital capacity (FVC) 72% predicted, FEV1/FVC = 86 %

Patient 2: Forced expiratory volume in one second(FEV1)60% predicted, forced vital capacity (FVC)85% predicted, FEV1/FVC = 62 %

Patient 3: Forced expiratory volume in one second(FEV1)100% predicted, forced vital capacity (FVC)101% predicted, FEV1/FVC = 80 %
OPTIONS
-Pulmonary fibrosis or kyphoscoliosis
-Asthma or chronic obstructive pulmonary disease (COPD)
-Asthma or normal
-COPD or normal
-Pulmonary fibrosis or normalThe following results have been obtained by your nurse at the respiratory clinic in the practice. All are male, non smokers.

Match each patient to the SINGLE MOST likely diagnostic option. Each option may be used once, more than once, or not at all.

Patient 1: Forced expiratory volume in one second(FEV1) 70% predicted, forced vital capacity (FVC) 72% predicted, FEV1/FVC = 86 %

Patient 2: Forced expiratory volume in one second(FEV1)60% predicted, forced vital capacity (FVC)85% predicted, FEV1/FVC = 62 %

Patient 3: Forced expiratory volume in one second(FEV1)100% predicted, forced vital capacity (FVC)101% predicted, FEV1/FVC = 80 %
OPTIONS
-Pulmonary fibrosis or kyphoscoliosis
-Asthma or chronic obstructive pulmonary disease (COPD)
-Asthma or normal
-COPD or normal
-Pulmonary fibrosis or normal

A

Patient 1 correct answer:Pulmonary fibrosis or kyphoscoliosis

Both the FEV1and the FVC are proportionally reduced.This is more consistent with restrictive lung disease such as pulmonary fibrosis or kyphoscoliosis.

Patient 2 correct answer: Asthma or chronic obstructive pulmonary disease (COPD)

The FEV1is reduced proportionally more than the FVC. Without further history and reversibility testing however it is not possible to distinguish Asthma from COPD.

Patient 3 correct answer: Asthma or normal

It is perfectly possible for a controlled asthmatic to have normal spirometry (and for that matter a normal peak flow). COPD by definition however would have an FEV1of < 80% and an FEV1 / FVC < 70% even in the treated state. Pulmonary fibrosis would be associated with

31
Q

Which ONE of the following features are indications for the use of long term oxygen therapy (LTOT) in chronic obstructive pulmonary disease (COPD)? Select ONE option only.

Select one:

A.

Forced expiratory volume in one second (FEV1)40% of predicted value

B.

Wheeze

C.

Oxygen saturations 88% on breathing air

D.

Partial pressure ofoxygen(PaO2) 7 kPa

E.

Smoker

A

Answer justification and feedback:The need for oxygen therapy is assessed by measuring arterial blood gases on two occasions, at least three weeks apart. Long-term oxygen should be offered to those with a partial pressure ofoxygen (PaO2) of < 7.3 kPa when stable.
Long-term oxygen should also be offered to those with an arterial PaO2of > 7.3 kPa and < 8 kPa when there is associated peripheral oedema, pulmonary hypertension, secondary polycythaemia or nocturnal hypoxaemia.

Resource:
HardingeM,AnnandaleJ,BourneS,et al.British Thoracic Society guidelines for home oxygen use in adults: accredited by NICE.Thorax2015;70:i1–i43.

The correct answer is:Partial pressure ofoxygen(PaO2) 7 kPa

32
Q

Which is the SINGLE MOST appropriate statement regarding the use of corticosteroids to treat an exacerbation of chronic obstructive pulmonary disease (COPD)? Select ONE option only.

Select one:

A.

A significant beneficial effect on mortality figures

B.

No benefit on symptoms

C.

Reduced risk of clinical deterioration

D.

Reduction in chest pain scores

E.

Reduction in sputum production

A

Answer justification and feedback:A Cochrane review showed that oral steroidsin the treatment of exacerbations of COPD reduces the likelihood of treatment failure andrelapseby one month, shortens the length of stay in hospital inpatients not requiring assistedventilationin intensive careandsome modest improvements in spirometric parameters.
Resources:
Walters J, Tan D, White C, et al.Do systemic corticosteroids improve treatment outcomes in flare-ups of chronic obstructive pulmonary disease?Cochrane Database of Systematic Reviews2014;9.

The correct answer is: Reduced risk of clinical deterioration

33
Q

A 19-year-old man with cystic fibrosis has frequent episodes of pulmonary infection requiring antibiotic treatment.

Which of the following organisms is the SINGLE MOST likely to be responsible? Select ONE option only.

Select one:
A.Haemophilus influenza
B.Escherischia coli
C.Pseudomonas aeruginosa
D.Streptococcus pyogenes
E.Aspergillus fumigatus
A

ANS C.

Answer justification and feedback: Staphylococcus aureusis the predominant cause of pulmonary infection in cystic fibrosis throughout childhood and the early teenage years, withHaemophilus influenzathe next most frequently causative organism.

In the late teenage years,Pseudomonas aeruginosabecomes more common, and remains responsible for 80% of pulmonary infection throughout adult life.

In addition to common bacterial pathogens, more unusual organisms may cause disease in lungs damaged by cystic fibrosis. Secondary colonisation by fungi is common, andAspergillus fumigatusis the cause of allergic bronchopulmonary aspergillosis in people with this condition.

Resources:
RCGP.Curriculum Topic Guides: respiratory health. 2019.
RCGP Learning.Respiratory health in general practice.
The correct answer is:Pseudomonas aeruginosa

34
Q

In the INITIAL assessment of chronic obstructive pulmonary disease(COPD), which TWO of the following investigations are recommended for ALL patients in addition to spirometry and a full blood count? Select TWO options only.

Select one or more:

A.

Chest X-ray

B.

Echocardiogram

C.

Serial peak flow measurements

D.

Urea and electrolytes

E.

Body mass index

F.

Lipid profile

G.

Oxygen saturation

H.

Electrocardiogram (ECG)

A

Answer justification and feedback:According toNational Institute for Health and Care Excellence (NICE) guidance, in addition to spirometry, it is recommended that all patients with a diagnosis of COPD have an initial full blood count, chest X-ray and body mass index measurement.
Resources:
RCGP.Curriculum Topic Guides: respiratory health.2019.
NICE.Chronic Obstructive Pulmonary Disease in Over 16s: diagnosis and management.2010.

The correct answers are: Body mass index, Chest X-ray

35
Q

A 40-year-old man with known asthma attends your surgery complaining of increasing wheeze in the past few hours.
Which ONE of the following signs would suggest an acute severe asthma episode in this patient? Select ONE option only.

Select one:

A.

Respiratory rate of 25 breaths/min or more

B.

Oxygen saturations less than 93%

C.Oxygen saturations less than 96%

D.Respiratory rate of 20 breaths/min or more

E.Heart rate of 108 beats/min or more

A

Answer justification and feedback: An acute severe asthma episode is defined as any one of:

Peak expiratory flow (PEF) 33–50% best or predicted

respiratory rate ≥ 25 breaths per minute

heart rate ≥ 110 beats per minute

inability to complete sentences in one breath

Resources:
BTS, SIGN. British Guideline on the Management of Asthma.2019.

The correct answer is: Respiratory rate of 25 breaths/min or more

36
Q

Following the 2014 National Review of Asthma Deaths, what number of courses of oral or intravenous steroids in the past 12 months should prompt referral to secondary care for optimisation of asthma treatment?

More than 1
More than 2
More than 3
More than 4
More than 5
A

2

37
Q

Following the 2014 National Review of Asthma Deaths, what number of courses of inhaled salbutamol in the past 12 months should prompt referral to secondary care for optimisation of asthma treatment?

More than 4
More than 6
More than 8
More than 10
More than 12
A

12

38
Q

62-year-old man with a history of recurrent lower respiratory tract infections is diagnosed as having bilateral bronchiectasis following a high resolution CT scan. Which one of the following is most important in the long term control of his symptoms?

Inhaled corticosteroids
Prophylactic antibiotics
Surgery
Postural drainage
Mucolytic therapy
A

Postural drainage

39
Q

One of your patients with difficult to control asthma has been started on omalizumab by the respiratory clinic.

Which one of the following statements regarding omalizumab is correct?

It causes weight gain in around 10% of patients
It is given as an intravenous infusion every 2 months
It can be used in patients aged 6 years and older
Leukotriene receptor antagonists and oral theophyllines should be stopped once omalizumab is commenced
It is classed as an ultra-long acting bronchodilator

A

C

40
Q

An 81-year-old man presents with a 10-day productive cough with clear sputum. Prior to this he had some coryzal symptoms and no fever. He is a non-smoker, has continued his activities of daily living and has not previously had similar symptoms. He has a history of hypertension and type 2 diabetes mellitus. A coronavirus swab was negative.

His observations are:

Temperature37.3º
Respiratory Rate26 breaths per minute
Blood Pressure134/86mmHg
Heart Rate86 beats per minute
O2Saturations97%

On examination, he has good air entry with a mild wheeze bilaterally. There is no dullness to percussion, crepitations or bronchial breathing.

Given the likely diagnosis, which of the following is the best immediate management?

Doxycycline
Prednisolone
Self care advice
Self care and smoking cessation advice
Smoking cessation advice
A

Doxycycline

41
Q

For a diagnosis of occupational asthma, which SINGLE percentage is the upper limit of variable peak expiratory flow (PEF) readings? Select ONE option only.

Select one:

A. 5

B. 10

C. 15

D. 20

E. 25

A

20%

42
Q
Which of the following can cause a flare in UC 
A. Paracetamol 
B. Codeine 
C. Aminosalicylate 
D. Amoxicillin 
E. Naproxen
A
  • Erythema Nodosum
  • Pyoderma gangrenosum
  • rarely Psoriasis

NB things like aphthous ulcers, episcleritis are also associated

43
Q
Which of the following is not a long term complication of Chrons 
A. Intestinal strictures 
B. Fistulas 
C. Malnutrition 
D. Vitamin B12 and folate deficiency 
E. Dermatitis Herpetiformis
A

E

DH is associated with Coelic not Crohns

44
Q
Which of the following can cause a flare in UC 
A. Paracetamol 
B. Codeine 
C. Aminosalicylate 
D. Amoxicillin 
E. Naproxen
A

NSAIDS

45
Q

Which skin conditions are associated with Crohns?

A
  • Erythema Nodosum
  • Pyoderma gangrenosum
  • rarely Psoriasis

NB things like aphthous ulcers, episcleritis are also associated

46
Q

Commonest extra intestinal manifestation of IBD?

A

Pausi or multi articular arthritis

47
Q

For a diagnosis of occupational asthma, which SINGLE percentage is the upper limit of variable peak expiratory flow (PEF) readings? Select ONE option only.

Select one:

A. 5

B. 10

C. 15

D. 20

E. 25

A

20%

48
Q

A young woman, on methadone maintenance, delivers a 3500g baby and discharges herself from hospital after 24 hours. She is breastfeeding. On the third day postnatally, she phones and tells you the baby seems very irritable, has a high pitched cry and is breathing very rapidly. You visit them.

Which of the following actions is the SINGLE MOST appropriate? Select ONE option only.

Select one:

A. Ask the mother to stop breast feeding

B. Ask the mother to reduce the methadone

C. Ask the health visitor to monitor and review

D. Admit the baby to hospital with the mother

E. Ask the mother to increase the methadone

A

D

49
Q

A 27-year-old patient with known heroin addiction on methadone maintenance therapy is ready for complete abstinence from all opioids. He is being considered for detoxification therapy.

What is the SINGLE MOST appropriate management option? Select ONE option only.

Select one:

A. Detoxification should be avoided

B. Detoxification should be performed using buprenorphine

C. Detoxification should be performed using methadone

D. Review in one month

E. Maintenance therapy should be continued

A

C: Methadone

50
Q

A 60-year-old man attends your surgery. He has a long history of heavy alcohol consumption with established alcoholic liver cirrhosis and oesophageal varices. He has been less well recently, despite having been abstinent from alcohol for over six months. He asks whether his liver will get better. You discuss the long term problems related to alcohol abuse.

What is currently thought to be the MOST EFFECTIVE evidence-based intervention strategy for reducing alcohol-related harm? Select ONE option only.

Select one:

A. Ensuring licensing laws are strictly adhered to

B. Limiting the advertising of alcohol

C. Making alcohol less affordable

D. Reducing the number of alcohol outlets

E. Reducing the number of hours/days alcohol is sold

A

C

51
Q

A 26-year-old nurse presents urgently with a history of visual loss in the right eye over the last two days associated with pain on moving her eye. She has been previously well.

WhichONE of the following options would indicate an afferent pupillary defect on the right? Select ONE option only.

Select one:
A.When a light is swung from eye to eye the right pupil dilates when light is shone into it
B.When a light is swung from eye to eye the left pupil dilates when light is shone into it
C.When a light is swung from eye to eye the right pupil constricts when light is shone into it
D.When a light is swung from eye to eye the right pupil dilates when light is shone into the left eye
E.When a light is swung from eye to eye the left pupil dilates when light is shone into the right eye

A

ANS C.

Answer justification and feedback:This is the classical ‘Marcus Gunn’ pupil. In the NORMAL patient BOTH pupils constrict when light is shone into EITHER side due to the pupillary and the consensual reflexes. Then they DILATE. If afferent impulses on the right side are delayed (due to, for instance, optic neuritis) as light is swung into the affected eye the consensual dilation from the (normal) left eye is more powerful than the light reflex in the affected eye. Therefore, PAROXYSMAL DILATATION is seen on the swinging light test in the AFFECTED (i.e. the right) eye. This phenomenon is best demonstrated with the light shone into the eyes alternately for 2–3 seconds with approximately one second in between.

The correct answer is: When a light is swung from eye to eye the right pupil dilates when light is shone into it

52
Q
A four-year-old girl attends with her mother. Concern is expressed regarding her eyes and the possibility that she may have a squint.
Which of the following examination techniques is NOT indicated? Select ONE option only.
Select one:
A.Visual acuity
B.Cover test
C.Corneal light reflex
D.Swinging light test
E.Ocular movements
A

ANS D.
Answer justification and feedback:Squint or strabismus is the term used to indicate ocular misalignment and it can occur in any direction. There are many causes. It is important to correctly diagnose this in young children as, if left untreated, the misaligned eye will lose visual acuity (amblyopia) due to disuse and this can be permanent.

Assessment includes:
• Facial appearance
• Corneal light reflex
• Fundoscopy
• Ocular movements
• Cover test
• Visual acuity
Resource:
RCGP.Curriculum Topic Guides: eyes and vision. 2019.
The correct answer is: Swinging light test
53
Q

A 76-year-old man attends the surgery complaining of worsening eyesight. He is the main carer for his disabled wife. He has a history of hypertension and age-related macular degeneration.

Which of the following health professionals can register a patient as ‘partially-sighted’ or ‘blind’? Select ONE option only.

Select one:

A.

Ophthalmologist

B.

Optometrist

C.

General practitioner

D.

Occupational therapist

E.

Social worker

A

Feedback

Your answer is correct.

Answer justification and feedback:Only a consultant ophthalmologist can register a patient as ‘partially-sighted’ or ‘blind’. A Certificate of Vision Impairment is completed, and this takes in to account both visual acuity and visual field measurements

Resource:

RNIB.The criteria for certification.

The correct answer is: Ophthalmologist

54
Q

For each patient with a painful red eye, select theSINGLE MOSTlikely diagnosis. Each option can be used once, more than once or not at all.

A. A 26-year-old man, with no significant past history, has a three-day history of increasing pain and redness of his left eye. He has been unable to wear his contact lenses due to the pain. He has blurred vision and is photophobic in this eye. On examination, he has pericorneal redness of the eye. His pupil reacts normally to light. Insertion of fluorescein reveals an irregular green patch on his cornea.

B. A 78-year-old woman with dementia is visited urgently by you. She is unable to give a history but the nursing home staff report that she has become increasingly distressed and has vomited twice. She is moaning and rocking back and forth holding her head. While examining her, you notice her right eye is red while the left is normal. The redness is around the cornea and the pupil is unreactive to light. Insertion of fluorescein reveals no staining.

C. A 32-year-old woman has an acutely painful, red, right eye. The pain is deep and boring in nature with extension of pain onto her face. She suffers from rheumatoid arthritis. On examination, there is marked vasodilation of the vessels all over the white of her eye. Visual acuity in the right eye is 6/18. Insertion of fluorescein reveals no staining.

All answer options:

Acute closed-angle glaucoma

Bacterial conjunctivitis

Episcleritis

Keratitis

Orbital cellulitis

Scleritis

Subconjunctival haemorrhage

A

Answer justification and feedback:
All answer options:

Acute closed-angle glaucoma

Bacterial conjunctivitis

Episcleritis

Keratitis

Orbital cellulitis

Scleritis

Subconjunctival haemorrhage

Patient 1 correct answer:Keratitis
Keratitis can cause ulceration of the cornea which can be sight threatening due to scarring if not treated rapidly. If suspected, an immediate ophthalmology referral is necessary.
Patient 2 correct answer:Acute closed-angle glaucoma
Acute closed-angle glaucoma necessitates immediate ophthalmology assessment to avoid loss of sight. Symptoms may be preceded by warning haloes and on examination the cornea will be oedematous and appear hazy.
Patient 3 correct answer:Scleritis
Unlike the mild sensitivity of episcleritis, true scleritis presents with severe, boring ocular pain which may also involve the adjacent head and facial regions. The scleral vessels are significantly dilated, as are the overlying vessels of the episclera and bulbar conjunctiva. The affected eye may be so injected in some cases that the eye actually takes on a deep red, almost purple, hue.
Scleritis is often associated with connective tissue diseases. It requires urgent ophthalmology assessment as systemic treatment may be required. Without treatment, permanent loss of vision may occur in the affected eye or even perforation of the globe. Any rheumatoid patient with a very painful eye should be referred for further assessment.
A drop of phenylephrine 2.5% causes visible blanching of the episcleral vessels in episcleritis, but will not do so in scleritis. Examination with a slit lamp microscope is also helpful in diagnosis.
Resource:
RCGP.Curriculum Topic Guides: eyes and vision.2019.

55
Q

A 35 year old heroin user chooses to undergo opiod detixification therapy. He had 60mg methadone and vomited an hour later.
How will you further manage this patient

  1. Administer 60mg methadone immediately
  2. Give half the original dose
  3. Give 45mg methadone
  4. Do not replace the dose.
A

4: do not replace the dose

56
Q

A 25-year-old male patient, with no significant past medical history, presents with a painful red right eye. He does not usually wear glasses, but on examination his visual acuity is 6/12 in the affected eye. The redness is concentrated around the cornea and his right pupil is smaller than his left.
Which of the following represents the SINGLE MOST likely diagnosis? Select ONE option only.

Select one:

A.

Viral conjunctivitis

B.

Glaucoma

C.

Iritis

D.

Allergic conjunctivitis

E.

Marginal keratitis

A

Answer justification and feedback: This patient has iritis. The symptoms/signs pointing to this diagnosis are: ‘circumlimbial’ pattern of injection, eye pain, reduction in visual acuity and pupillary change.
Acute conjunctivitis usually presents with diffuse conjunctival injection and normal visual acuity; there should not be any pupil changes. In this age group acute glaucoma is unlikely especially in the absence of any ophthalmic history.

The correct answer is: Iritis

57
Q

A 50-year-old, short-sighted, man presents with painless loss of left vision for one day. The day before, he saw bright flashing lights ‘like lightening’ and lots of small black spots “floating around” in his left field of vision. He then noticeda solid dark shadow moving in from the edge of the vision in his left eye.
What is the SINGLE MOST likely cause? Select ONE option only.

Select one:

A.

Ischaemic optic neuropathy

B.

Retinal detachment

C.

Central retinal artery occlusion

D.

Central retinal vein occlusion

E.

Acute closed angle glaucoma

A

Answer justification and feedback:Symptoms of vitreous detachment– flashes of light and floaters– are usual in tractional detachment and may precede retinal detachment by minutes or years.
Retinal detachment is usually noticed as a ‘shadow’ or ‘curtain’ spreading across the field of vision.
In acute closed angle glaucoma, there is a sudden severe rise of intra-ocular pressure with an acute loss of vision in the affected eye, severe periocular pain and congestion. Nausea and vomiting are common.
Blockage of the central retinal artery or one of its branches should be considered in all cases of sudden, painless loss of vision. However, it is relatively uncommon, and usually affects the elderly.
Central retinal vein occlusion may present as a sudden painless loss of vision. It is less common than an occlusion of a branch vein and is less abrupt than a central retinal artery occlusion.
Ischaemic optic neuropathy describes sudden loss of vision due to occlusion of the posterior ciliary arteries. It can be caused by giant cell arteritis, where prompt use of steroids can prevent visual loss.

The correct answer is: Retinal detachment

58
Q

Which is the SINGLE MOST appropriate non-drug intervention for managing social anxiety disorder in adults? Select ONE option only.

Select one:

A.

Eye movement desensitisation and re-processing (EMDR)

B.

Psychodynamic psychotherapy

C.

Individual cognitive behavioural therapy (CBT)

D.

Flooding therapy

E.

Mindfulness-based intervention

A

Feedback

Your answer is correct

Answer justification and feedback:Initial intervention should be with individual CBT specific to social anxiety disorder. If this is declined, CBT-based supported self-help can be offered.
Resource:
NICE.Social Anxiety Disorder: recognition, assessment and treatment(Clinical Guideline 159).2013.

The correct answer is: Individual cognitive behavioural therapy (CBT)