QC and QA

Question 1

a system that ensures accuracy and precision in the laboratory

Answer 1

Quality Control

Question 2

The ability of an analytical method to measure the smallest concentration of the analyte of interest

Answer 2

Sensitivity

Question 3

the ability of an analytical method to measure only the analyte of interest

Answer 3

Specificity

Question 4

The nearness and closeness of the assayed value to the true or target value.

Answer 4

Accuracy

Question 5

Used to assess presence of error (inaccuracy) in actual patient patient sample

Answer 5

Sample Comparison Study

Question 6

Determines if specific compounds affect the laboratory test like hemolysis, turbidity and icteric

Answer 6

Interference study

Question 7

Determines how much of the analyte can be identified in the sample

Answer 7

Recovery study

Question 8

The ability of an analytical method to give repeated results on the same sample that agree with one another

Answer 8

Precision or Reproducibility

Question 9

The ability of an analytical method to maintain accuracy and precision over an extended period of time

Answer 9

Reliability

Question 10

The degree by which a method is easily repeated

Answer 10

Practicability

Question 11

the ability of the analytically method to detect the proportion of individuals with the disease

Answer 11

Diagnostic Sensitivity

Question 12

The ability of the analytical method to detect the proportion of individuals without the disease

Answer 12

Diagnostic Specificity

Question 13

Control samples and px samples
Inside the lab
Daily monitoring of accuracy and precision
Random and systematic error
One week cycle

Answer 13

Intralab QC

Question 14

Proficiency testing
Long term accuracy
Determines state of the art lab
College of American Pathology

Answer 14

Interlab QC

Question 15

It is present in all measurements. It is due to chance.
Type of error which varies from sample to sample

Answer 15

Random Error

Question 16

It is an error that influences observations consistently in one direction (constant difference)

Answer 16

Systematic error

Question 17

It is the basis for varying differences between repeated measurements-variations in technique

Answer 17

Random error

Question 18

It is a measure of the agreement between the measured quantity and the true value

Answer 18

Systematic error

Question 19

Measure of central tendency

Answer 19

Mean

Question 20

Used to observe values of control materials overtime to determine reliability of the analytical method

Answer 20

Quality Control Chart

Question 21

Occurs when the data set can be accurately described by the SD and the mean

Answer 21

Gaussian Curve (Bell Shaped Curve)

Question 22

Calculates the difference between QC and the target means. Earliest indication of systematic error

Answer 22

Cumulative Sum Graph (CUSUM)

Question 23

Deterioration of reagents

Answer 23

Trend

Question 24

Improper calibration of the instrument

Answer 24

Shift

Question 25

The most widely used QC chart in the clinical laboratory

Answer 25

Shewhart Levey Jennings Chart

Question 26

Use to compare results obtained on high and low control serum from different laboratories

Answer 26

Youdin/Twin Plot

Question 27

A performance improvement program, in which the goal is to improve the process by eliminating variations or errors; improved performance,improved performance quality, improved bottom line

Answer 27

Six sigma

Question 28

A system for reducing waste “Nonvalued activities “ esp in production or manufacturing processes

Answer 28

Lean system

Question 29

The most common used patient based- QC technique

Answer 29

Delta check

Question 30

Type of analytical testing performed outside the confines and central laboratory

Answer 30

POCT