QBC Star Flashcards
What is the most frequently ordered Lab
CBC
RBC Indices
- Mean corpuscular Volume (MCV)
- Mean Corpuscular Hgb (MCH)
- Mean Corpuscular Hgb concentration (MCHC)
- RBC Distribution Width (RDW)
Red Blood Count ranges in adults
Male: 4.5-5.9 x 106 cell/uL
Females: 4.5-5.1 x 106 cells/uL
Normal Adult Hemoglobin ranges in adults
Males: 14-17.5 g/dL
Females> 12.3-15.3 g/dL
What is the critical low value for hemoglobin?
< 8 g/dL
What is the assessment of the size and HgB content of RBC?
Mean Corpuscular Volume (MCV)
Normal range for mean corpuscular volume?
76-96fL/cell
What is an associated with an increase the MCV ?
Vitamin B12 or folate deficiency
What is associated with a decrease in MCV?
Abnormality in Hgb synthesis. Most likely caused by an iron deficiency.
What is the normal range for Mean Corpuscular Hemoglobin (MCH)
27-32 pg/cell
Increase in Mean Corpuscular Hemoglobin?
Vitamin B12 or folate deficiency
Decrease in Mean Corpuscular Hemoglobin?
Iron Deficiency.
What is the formula for Mean Corpuscular Hemoglobin?
MCH = Hgb x 10 / RBC count
What is the formula for Mean Corpuscular Hemoglobin Concentration (MCHC)?
MCHC = Hgb/Hct x 100
What is the normal range for platelet count?
150,000 - 400,000
What is an abnormally high platelet count called?
thrombocytosis
What can cause thrombocytosis?
Splenectomy, Trauma, Iron Deficiency Anemia, or Cirrhosis
What is an abnormally low platelet count called?
Thrombocytopenia
What is the critical low value for Platelets?
< 20,000
When is thrombocytopenia seen?
TTP, DIC, Leukemia, and Metastatic Cancers
What is the normal White Blood Cell Count
4.5 - 11.0 x 1.3
What is the critical low value for WBCs
< 2,000
What can cause leukopenia?
Bone Marrow deficiency (tumor, infection)
Collagen-vascular diseases
Disease of the liver or spleen
Radiation therapy or exposure
What can cause leukocytosis?
- Anemia
- Bone Marrow Transplant
- Infectious Diseases
- Leukemia
- Tissue Damage
- Inflammatory Diseases
Agranular Lymphocytes
Bands
The ratio of the volume of erythrocytes to that of whole blood
Hematocrit
Normal Hematocrit value for men and women
Male: 42% - 52%
Female: 37% - 47%
Hematocrit value above the reference interval of age and sex
Polycythemia
Mean Corpuscular Hemoglobin Concentration
MCHC = Hgb/Hct x 100
Spontaneous bleeding can occur at what level, this is considered life-threatening
20,000 per microliter
Three types of granulocytes
Neutrophil: Most abundant
Eosinophil: Inflammatory response
Basophil: Histamine, heparin, platelet activating factor
used to describe malignant appearing lymphocyte cells
Atypical Lymphocytes
Used to describe benign or formed lymphocytes
Reactive Lymphocytes
Causes of reactive lymphocytes
Viral - HIV, chicken pox, EBV, influenza, rubella
Bacterial - Pertussis, Parathyroid fever
Drug Reaction - During recovery from acute infection