Qbank1 Flashcards
- The resting membrane potential of a cell is the consequence of which of the following concentrations of ions?
(A) High K+ and Cl− outside the cell and high Na+ and large anions inside the cell.
(B) High K+ and Na+ outside the cell and high Cl− and large anions inside the cell.
(C) High Cl− and Na+ outside the cell and high K+ and large cations inside the cell.
(D) High Ca2+ and Na+ outside the cell and high K+ and large cations inside the cell.
c
- Membrane proteins perform the following functions EXCEPT one. Which One?
(A) form the glycocalyx.
(B) act as receptor proteins.
(C) form pores to allow the passage of small solutes.
(D) behave as enzymes.
a
- Which of the following is correct for intra-cellular fluid (ICF) and extra-cellular fluid (ECF)?
(A) the ECF is part of the ICF
(B) the majority of the body’s water is in the ECF
(C) the ICF contains more sodium than the ECF
(D) the ICF contains more potassium than the ECF
d
- Which is not the ‘’principal carrier modes’’?
(A) facilitated diffusion
(B) passive diffusion
(C) primary active transport
(D) secondary active transport
b
- The transport maximum (Tm) is the intersection of which two concentration lines?
(A) simple transport and primary active transport
(B) facilitated diffusion and secondary active transport
(C) simple diffusion and Carrier mediated transport
(D) simple diffusion and primary active transport
c
- Which is not “Second messengers’’
(A) cAMP
(B) cGMP
(C) IP3
(D) ATP
d
- Which is not the ‘’Ion-channel structure’’?
(A) Activation
(B) Selectivity
(C) Conductance
(D) Convenience
d
- ____?____: Translocate to the nucleus and bind to hormone response elements within the promoter region of target genes.
(A) Intracellular receptors
(B) Catalytic receptors
(C) G protein–coupled receptors
(D) All of the above
a
- Which resting potential of typical nerve cell is correct?
(A) -100mV
(B) -70mV
(C) 90mV
(D) 1000mV
b
- Which ion is involved in contraction of muscle cells?
(A) Na+
(B) Ca2+
(C) K+
(D) Cl-
b
- In voltage-gated ion channels, which one of six spanning domains is for voltage sensory?
(A) S1
(B) S2
(C) S3
(D) S4
d
- Which of the following is not belonging to ligand-gated groups?
(A) Cys-loop superfamily
(B) Ionotropic glutamate receptors
(C) Sensory Channels
(D) ATP receptors
c
- A researcher examined the epithelial cells of the small intestine in patients with inflammatory bowel disease and found that the affected area had lower electrical impedance, whereas the healthy area had higher electrical impedance. What is inferred to be a characteristic of healthy epithelial cells?
(A) There is a weaker trans-epithelial ion gradient.
(B) is a transport protein that is specialized for iso-permeability.
(C) has a thicker basement membrane.
(D) The tight junctions are highly impenetrable.
d
- A 52-year-old woman presented with palpitations and dizziness. An electrocardiogram shows atrial fibrillation due to a high expression of connexin type 43. Which of the following is the best description of a normal connexin?
(A) It opens during depolarization of the cell membrane
(B) Highly ion selective
(C) Mediates Ca2+ flow from extracellular to intracellular
(D) Aids in the transfer of electrical current between tissues.
d
- Hypokalemia is rare in healthy individuals. Which of the following would tend to increase 𝐾+ uptake via the transport epithelium and be transferred to the circulatory system?
(A) Negative potential differences in the lumen
(B) Increased intercellular water uptake
(C) Increased sodium and potassium pumping activity
(D) High intercellular potassium concentration.
b
- Which of the following coefficients measures the ease with which a solute crosses the plasma membrane?
(A) Cell constant
(B) Fugacity coefficient
(C) Activity coefficient
(D) Reflection coefficient
d
- In what ways do cells not respond to changes in osmotic pressure?
(A) RVI
(B) RVD
(C) Change the composition of the cell membrane
(D) None of above
c
- Which of the following is not a parameter required to calculate osmotic pressure?
(A) Solute concentration
(B) Absolute temperature
(C) Gas constant
(D) All of the above
d
- What is the main buffer for interstitial fluid?
(A) protein
(B) HPO42-
(C) HCO3-
(D) Hemoglobin
c
- What is the most abundant monovalent cation in a cell?
(A) Na+
(B) Rb+
(C) K+
(D) Choline
c
- Which of the following is the optimum pH value for extracellular fluid?
(A) 6.5
(B) 7.0
(C) 7.4
(D) 7.8
c
- A 52-year-old woman presented with palpitations and lightheadedness. Electrocardiogram showed atrial fibrillation due to high expression of connexin type 43. Which of the following is the best description for connexins?
(A) opens when the cell membrane is depolarized
(B) highly ion-selective
(C) only in the heart
(D) Facilitates the transfer of electricity between tissues
d
- A researcher examined small intestinal epithelial cells from patients with inflammatory bowel disease and found that the affected areas had lower electrical resistance, while healthy areas had higher electrical resistance. Which is an inference for healthy epithelial cells?
(A) Has a weak transepithelial ion gradient
(B) specialized isotonic transport protein
(C) have a thicker basement membrane
(D) Tight junctions are highly impenetrable
d
- Hypokalemia is rare in healthy individuals. Which of the following tends to increase K+ uptake via the transport epithelium for transfer to the circulatory system?
(A) chamber negative potential difference
(B) Increased water uptake between cells
(C) Increased sodium potassium pump activity
(D) top glucose co-transport
b
- Which of the following is the insulating material that enhances signal-transmission rate?
(A) Dentrites
(B) Myelin
(C) Axon hillock
(D) Soma
b
- Which of the following is not amino acid as neurotransmitter?
(A) Glycine
(B) Dopamine
(C) Aspartate
(D) Glutamate
b
3.Which of the following is the correct order of layers from inner to outside peripheral nerve?
(A) Epineurium -> Fascicle -> Perineurium
(B) Perineurium -> Nerve fiber -> Epineurium
(C) Nerve fiber -> Perineurium -> Epineurium
(D) Nerve fiber -> Epineurium -> Perineurium
c
- Which of the following is not cerebral cortex?
(A) Primary sensory area
(B) Brainstem
(C) Supplementary motor area
(D) Associative area
b