Qbank Pharm

Question 1

Low ferritin indicates

Answer 1

Iron deficiency

Question 2

Low transferrin indicates

Answer 2

Anemia of chronic disease

Question 3

Volume of distribution

Formula

Answer 3

Vd= (t1/2 * clearance) / 0.7

Question 4

Fever, pruritus, arthropathy

Treatment

Answer 4

Serum-like sickness reaction

Antihistamines and corticosteroid therapy

Question 5

Serum sickness drugs ?

Answer 5

Cephalosporins (cefaclor)
Penicillin 
TMP-SMX 
Vaccines 
Antitoxins 
Tetracyclines 
Captopril 
Ciprofloxacin

Question 6

P450 inducers ?

Answer 6

Anticonvulsants (barbit, phenit,carbamazep)
Antibiotics (rifampin)
Chronic alcohol
Glucocorticoids

Question 7

P450 inhibitors ?

Answer 7

Antiulcer medications (cimetidine, omeprazol)
Antibiotics (chloramphenicol, macrolides, ritonavir, ketoconazole)
Acute alcohol

Question 8

Steady state concentration (Css)

Answer 8

Css= dosing rate / clearance

Question 9

Jarisch - herxheimer reaction

Treatment

Answer 9

Monoclonal ab to TUMOR NECROSIS FACTOR ALPHA

Question 10

Earliest sign of salicylate intoxication ?

Answer 10

Tinnitus

Question 11

Drug assoc w/heart failure, hepatotoxicity and weight gain

Answer 11

Thaizolidinedione

Question 12

Heroin

Answer 12

Mu receptor stimulating

Question 13

Meningitis in neonates

Treatment ?

Answer 13

CEFOTAXIME

* never use ceftriaxone : biliary sludge *

Question 14

Rash to pen

Answer 14

Use ceph

Question 15

Anaphylaxis to pen

Answer 15

Use non b lactam

Question 16

Chlamydia

Treatment

Answer 16

Azithromycin single dose OR

Doxycycline for 7 days

Question 17

Ricketts in pregnancy

Answer 17

Cloramphenicol

Question 18

Macrolides

Answer 18

MAC - mycoplasma
Motilin (stimulate)
Methylation (mode of resistance)

Question 19

Serious gram + where vanco didnt work

Answer 19

Quinupristin/dalfopristin

Linezolid

Question 20

TMP - SMX

Answer 20

P jirovecci (linf T CD4 < 200)
UTI
Listeria

Question 21

TMP - SMX

Side effect in neonates

Answer 21

Kernicterus

Question 22

Steven Johnson syndrome

Answer 22

Lamotrigine
Carbamazepine
Sulfonamides

Question 23

Phototoxicity

Answer 23

Fluoroquinolones 
o
Tetracyclines 
o
Sulfonamides

Question 24

Gram neg

Treatment

Answer 24

3rd gen ceph

Quinolones

Question 25

Comm -acquired pneumonia | Treatment

Answer 25

Levofloxacin

Question 26

Metronidazole Spectrum GET BaC on the metro G

Answer 26

Giardia, Entamoeba, Trichomonas Bacteroides, Clostridium Gardnerella

Question 27

Chlamydia | Treatment

Answer 27

Azithromycin or doxycycline

Question 28

MAC MACs For MAC

Answer 28

Prophylaxis: azithro x1wk OR clarithro (daily) Treatment: clarithro + ethambutol +/- rifabutin

Question 29

Histamine release

Answer 29

Morphine (⬆️ ICP) Vanco Amphotericin B

Question 30

Nephrotoxicity

Answer 30

Aminoglycosides Cisplatin Amphotericin B