Qbank Pharm Flashcards
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Low ferritin indicates
Iron deficiency
Low transferrin indicates
Anemia of chronic disease
Volume of distribution
Formula
Vd= (t1/2 * clearance) / 0.7
Fever, pruritus, arthropathy
Treatment
Serum-like sickness reaction
Antihistamines and corticosteroid therapy
Serum sickness drugs ?
Cephalosporins (cefaclor) Penicillin TMP-SMX Vaccines Antitoxins Tetracyclines Captopril Ciprofloxacin
P450 inducers ?
Anticonvulsants (barbit, phenit,carbamazep)
Antibiotics (rifampin)
Chronic alcohol
Glucocorticoids
P450 inhibitors ?
Antiulcer medications (cimetidine, omeprazol)
Antibiotics (chloramphenicol, macrolides, ritonavir, ketoconazole)
Acute alcohol
Steady state concentration (Css)
Css= dosing rate / clearance
Jarisch - herxheimer reaction
Treatment
Monoclonal ab to TUMOR NECROSIS FACTOR ALPHA
Earliest sign of salicylate intoxication ?
Tinnitus
Drug assoc w/heart failure, hepatotoxicity and weight gain
Thaizolidinedione
Heroin
Mu receptor stimulating
Meningitis in neonates
Treatment ?
CEFOTAXIME
* never use ceftriaxone : biliary sludge *
Rash to pen
Use ceph
Anaphylaxis to pen
Use non b lactam