Qbank Pharm Flashcards

All

1
Q

Low ferritin indicates

A

Iron deficiency

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Low transferrin indicates

A

Anemia of chronic disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Volume of distribution

Formula

A

Vd= (t1/2 * clearance) / 0.7

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Fever, pruritus, arthropathy

Treatment

A

Serum-like sickness reaction

Antihistamines and corticosteroid therapy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Serum sickness drugs ?

A
Cephalosporins (cefaclor)
Penicillin 
TMP-SMX 
Vaccines 
Antitoxins 
Tetracyclines 
Captopril 
Ciprofloxacin
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

P450 inducers ?

A

Anticonvulsants (barbit, phenit,carbamazep)
Antibiotics (rifampin)
Chronic alcohol
Glucocorticoids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

P450 inhibitors ?

A

Antiulcer medications (cimetidine, omeprazol)
Antibiotics (chloramphenicol, macrolides, ritonavir, ketoconazole)
Acute alcohol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Steady state concentration (Css)

A

Css= dosing rate / clearance

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Jarisch - herxheimer reaction

Treatment

A

Monoclonal ab to TUMOR NECROSIS FACTOR ALPHA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Earliest sign of salicylate intoxication ?

A

Tinnitus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Drug assoc w/heart failure, hepatotoxicity and weight gain

A

Thaizolidinedione

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Heroin

A

Mu receptor stimulating

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Meningitis in neonates

Treatment ?

A

CEFOTAXIME

* never use ceftriaxone : biliary sludge *

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Rash to pen

A

Use ceph

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Anaphylaxis to pen

A

Use non b lactam

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Chlamydia

Treatment

A

Azithromycin single dose OR

Doxycycline for 7 days

17
Q

Ricketts in pregnancy

A

Cloramphenicol

18
Q

Macrolides

A

MAC - mycoplasma
Motilin (stimulate)
Methylation (mode of resistance)

19
Q

Serious gram + where vanco didnt work

A

Quinupristin/dalfopristin

Linezolid

20
Q

TMP - SMX

A

P jirovecci (linf T CD4 < 200)
UTI
Listeria

21
Q

TMP - SMX

Side effect in neonates

A

Kernicterus

22
Q

Steven Johnson syndrome

A

Lamotrigine
Carbamazepine
Sulfonamides

23
Q

Phototoxicity

A
Fluoroquinolones 
o
Tetracyclines 
o
Sulfonamides
24
Q

Gram neg

Treatment

A

3rd gen ceph

Quinolones

25
Q

Comm -acquired pneumonia

Treatment

A

Levofloxacin

26
Q

Metronidazole
Spectrum
GET BaC on the metro G

A

Giardia, Entamoeba, Trichomonas
Bacteroides, Clostridium
Gardnerella

27
Q

Chlamydia

Treatment

A

Azithromycin or doxycycline

28
Q

MAC

MACs For MAC

A

Prophylaxis: azithro x1wk OR clarithro (daily)
Treatment: clarithro + ethambutol +/- rifabutin

29
Q

Histamine release

A

Morphine (⬆️ ICP)
Vanco
Amphotericin B

30
Q

Nephrotoxicity

A

Aminoglycosides
Cisplatin
Amphotericin B