Qbank/MKSAP Flashcards
A patient has a blue toe 3 days following cardiac cath s/p MI. What is the most likely cause?
Dislodged atheroembolism during cath
Criteria of metabolic syndrome? (5)
Abdominal obesity- waist circumference > 40 in men, 35 in women Fasting glucose > 100 BP > 130/80 TGs > 150 HDL <50 in women
How does guillan barre cause respiratory failure? What is the best test to monitor?
Muscle weakness
Vital capacity
When should tpa be used in strokes? Contraindications?
Within 3 hours and CT shows no brain bleed
Contraindicated when- hx of stroke in past 3 months, hx of intracrial bleed, major surgery, MI, active bleed
Why is it important to remove clothing soaked in vomit due to an organophosphate poisoning?
transcutatneous absorption
What is different about vitamin D deficiency in adults compared to children?
Adults have defective bone mineralization
Children have defective bone AND cartilage mineralization
How do you definitively diagnose bronchiectasis?
High resolution CT scan
Which tests should be performed at the diagnosis of HTN? (4)
Urinanalysis
CMP
Lipid profile
EKG
A patient 2 months s/p MI comes in with persistent ST elevation and deep Q waves- what complication has occurred?
Ventricular aneurysms
Papillary muscle rupture typically occurs between 2 days a a week
A patient slaps his foot as it hits the ground while he walks- what vertebrae could be damaged?
L5 radiculopathy
Others causes include neuropathy and trauma
A patient has a dull hypomobile tympanic membrane and HIV- what is the cause?
Serous otitis media or non infectious effusion
A patient has X-ray showing expansile and eccentrically lytic area in epiphysis of distal femur- likely diagnosis?
Giant cell tumor- this is a soap bubble lesion
What restrctive lung disease is associated with a normal or increased FRC?
Ankylosing spondylitis- due to chest wall motion restriction
What are EPO levels in PV?
Low- the increase in RBC is EPO independent
What is the best treatment for acute rejection of a kidney transplant?
IV steroids regardless of cause
What is amaurosis fugax? What is it a warning since of?
Painless loss of vision due to emboli
Warning sign of a stroke
An anterior cerebral artery stroke has what deficits?
Contralateral motor deficits more pronounced in lower limb than upper limb
A middle cerebral artery stroke has what deficits?
Contralateral motor deficits more pronounced in upper limbs than lower limbs +/- aphasia
A middle aged woman presents with pruritis, jaundice, xanthelasmas and is positive for anti-mitochondrial antibodies- what is the best treatment? Diagnosis?
Ursodeoxycholic acid
Primary biliary cirrhosis
What are some manifestations of systemic sclerosis?
GERD, R heart failure, HTN, anti-topoisomerase antibodies, pulmonary fibrosis
What is the treatment for cat scratch disease?
Azithromycin for 5 days
How does sodium bicarbonate help with treatment of TCA overdose?
Alleviates depressive action on Na channels by increasing extracellular Na
Patient’s with suspected ACS should be administered what ASAP?
Aspirin, decreases mortality
Why would someone who received multiple units of pRBC have parasthesia?
Blood products can have large amounts of citrate which chelates Ca and causes hypocalemia
A patient has leukocytosis following an asthma exacerbation- why?
Probably received glucocorticoids which mobilize the marginal pool of neutrophils
A patient with HTN and a fib comes in with dry skin, weight gain, fatigue, and difficulty concentrating. What medication could be responsible?
Amiodarone- it is inducing hypothyroidism
Also look out for pulmonary fibrosis and hepatotoxicity
How do you treat pseudotumor cerebri?
LP to let out some of the pressure- until opening pressure < 20
What 3 organs are typically affected by GVH disease?
Liver, skin, intestine
What are some signs of drug induced interstitial nephritis?
acute renal failure, arthralgia, rash, and WBC casts of eosinophils
What are causes of atrial fibrillation?
HTN, valvular disease, hyperthyroid, drugs, pulmonary embolism, CHF
What is the best treatment for someone with EKG changes and hyperkalemia?
IV Ca gluconate
A patient undergoes a CABG procedure and requires 10 units of pRBC and develops hypotension during the procedure. He then develops jaundice on POD 3- why?
Post-op cholestasis
What is the SAAG?
Serum ascites albumin gradient- serum albumin - fluid albumin
> 1.1 is consistent w/ portal HTN
What vaccine should people over 65 get who already had pneumovax?
Varicella
What one time screening should be done in patients >65 who have 10 year pack history?
Abdominal ultrasound to rule out AAA
What is the treatment for acute cocaine intoxication?
BZDs
What medication has been proven to decrease the frequency of relapse with alcoholics?
Naltrexone
A patient with prostate cancer now has low back pain- best diagnostic test?
MRI of thoracolumbar spine to look for bony metastasis
How to diagnose and treat chronic cough NOT caused by GERD, allergic rhinitis, or asthma?
Inhaled albuterol trial- any response could mean eosinophilic bronchitis
Tx of chronic cough is antihistamines and decongestants
A patient has unsuccessfully tried to lose weight with diet and exercise for 3 years- what is the next step in treatment?
Try orlistat before surgery
What is a possible treatment for heavy menstrual bleeding?
medroxyprogesterone acetate
A woman with amenorrhea has a positive progestin challenge- menses occurred after progestin- diagnosis?
Chronic anovulation with estrogen present
What is the proper screening test for hearing impairment in the elderly?
Whisper test
What is be best treatment for disequilibrium causing falls in the elderly?
Physical therapy
A patient comes in with a BP of 162/100- what is the best treatment?
Stage 2 HTN needs 2 DRUGS- HCTZ and ACEI
What are some lung parameters seen in neuromuscular respiratory failure?
Normal FEV/FVC ratio
Increased RV
Low maximum respiratory pressures
A patient with systemic sclerosis has normal lung volumes but worsening dyspnea on exertion- what lung pathology could be occurring?
Pulmonary arterial HTN
What constitutes a complicated pleural effusion and what is the treatment?
pH < 7.2, glucose < 60, LDH > 1000
Treat w/ chest tube b/c will respond poorly to antibiotics
A patient has a lymphocyte dominated pleural effusion- next step in management?
Pleural biopsy for TB
A patient’s well controlled asthma becomes much worse following a URI- what is the best treatment?
Short dose of oral corticosteroids to help patient regain control of asthma
A patient is having a COPD exacerbation- what can reduce the need for intubation?
Noninvasive positive pressure ventilation
When is lung transplant considered in COPD?
PCO2 > 50 during hospitalization, FEV not > 20%, DLCO < 20%
A 65 year old woman has back pain, acute kidney injury, and hypercalcemia- diagnosis?
Think multiple myeloma until proven otherwise
Look for lytic lesions on X ray or Bence Jones protein in urine
A patient begins taking amitriptyline then comes to the ED with abdominal pain- what is happening and what is treatment?
Urinary retention due to anticholinergic effects of TCAs
Urinary cath is diagnostic and therapeutic
What is the initial treatment for agitation in the elderly?
Low dose haloperidol
A patient with hx of NSCLC has a new brain mass at gray-white matter junction- treatment?
Resect mass
Whole brain radiation
What is the treatment for inferior wall MI?
Fluid resuscitation to increase RV stroke volume
What will a right heart cath show in PE?
Increased RA pressure, increased pulmonary artery pressure, normal PCWP, RV dilatation
Which kidney disease is associated with HIV?
FSGS
A patient develops PNA after being intubated and is not responding to ceftriaxone- next step?
Zosyn to cover for pseudomonas
How do you treat someone with an area of erythema and induration that grows gram positive branching bacteria?
IV penicillin
What is the treatment for influenza?
Oseltamivir
Pleural effusion fluid has a very high amylase- what is the diagnosis?
Esophageal perforation
Look for subcutaneous emphysema, mediastinal widening
A patient with AML s/p bone marrow transplant has diarrhea and pneumonitis- diagnosis?
CMV infection most likely
What leads to edema in CHF?
Constriction of renal arterioles and renin angiotensin system activation
Both tacrolimus and cyclosporine cause nephrotoxicity- what is a side effect of cyclosporine that can help differentiate the two?
gum hypertrophy and hirtuism
What is the major toxicity of mucophenolate?
Bone marrow suppression
What is the major toxicity of azathioprine?
diarrhea, leukopenia, hepatotoxicity
A patient comes in with CML what show treatment focus on?
Targeting abnormal tyrosine kinase activity- imatinib is one choice
What is the pathophysiology behind carpal tunnel syndrome?
Deposition of mucopolysaccharide protein complexes
What is seen in hereditary spherocytosis with respect to MCHC and RDW and why?
Increased MCHC and RDW due to membrane loss and RBC dehydration
An HIV patient has a bright red firm friable nodule- diagnosis and treatment?
Bacillary angiomatosis
Treat with erothromycin
How can acute pancreatitis cause hypotension?
Intravascular volume loss due to increased capillary permeability
A patient with HIV comes in with pain swallowing and substernal burning? Diagnosis and treatment
Esophagitis, most likely from candida
Therefore, treat with fluconazole
Candida»> than CMV
What is the classic scenario of dequervian’s synovitis?
Newborn mother having pain when she lifts her infant from a crib
Finklestein test: Passive stretching of tendons by moving flexed thumb into the palm
What are 2 common side effects of EPO therapy?
Worsening of HTN
Headaches
A patient with a h/o radiation therapy presents with hepatomegaly, ascites and increased JVP- diagnosis?
Constrictive pericarditis
How can PCWP differentiate between cardiogenic and hypovolemic shock?
Will be high in cardiogenic shock and low in hypovolemic
What are some complications of acute pancreatitis?
Pleural effusion, ARDS, ileus, and renal failure
Typically caused by activation of pancreatic enzymes
How can nephrotic syndrome cause hypercoaguability?
Increased loss of pro-coagulation proteins due to proteinuria