QAS: Drug Therapies Protocol Flashcards

1
Q

Oxygen: Metabolism

A

Nil

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2
Q

Oxygen: Indications

A

A wide range of conditions resulting (potentially) in systemic and/or localised hypoxia

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3
Q

Oxygen: Contraindications

A

Paraquat poisoning
Bleomycin therapy

Avoid Oxygen unless Pt is hypoxaemic (SpO2 > 88 %)

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4
Q

Oxygen: Side Effects

A

Hypoventilation in some COPD Pt with hypoxic drive

Drying of mucosal membranes

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5
Q

Oxygen: Presentations

A

Size C: 450 L Oxygen

Size D: 1600 L Oxygen

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6
Q

100% Oxygen should be administered for:

A

Intra-arrest
CO poisoning
Cyanide poisoning
Preoxygenation for RSI

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7
Q

Oxygen should be titrated to achieve an SpO2 of 88 - 92% for:

A
Paraquat toxicity
Bleomycin treatment 
Obesity 
COPD
Cystic fibrosis 
Neuromuscular disease
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8
Q

Oxygen should be titrated to achieve an SpO2 of 92- 96% for:

A

All other presentations

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9
Q

Oxygen: Driving accidents

A

Administer high-flow Oxygen

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10
Q

For Pts with COPD, a nebulised salbutamol must be delivered via nebuliser mask at a rate of:

A

6 L/minute

8 L/ minute for all other Pts

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11
Q

Methoxyflurane: Drug Class

A

Analgesic

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12
Q

Methoxyflurane: Pharmacology

A

Volatile, self-administered inhalation analgesic
Short-term pain relief
Greater propensity to diffuse into fatty tissue

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13
Q

Methoxyflurane: Metabolism

A

By the liver

Excreted by the lungs

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14
Q

Methoxyflurane: Indications

A

Pain

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15
Q

Methoxyflurane: Contraindications

A

Allergy/adverse drug reaction
Pts < 1 year old
History of significant liver/renal disease
History of malignant hyperthermia

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16
Q

Methoxyflurane: Precautions

A

ALOC

Intoxicated

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17
Q

Methoxyflurane: Side Effects

A

ALOC
Cough
Renal/hepatic failure

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18
Q

Methoxyflurane: Presentation

A

3 mL bottle

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19
Q

Methoxyflurane: Onset and Duration

A

Onset @ 1 - 3 minutes

Duration @ 5 - 10 minutes

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20
Q

Methoxyflurane: Schedule

A

Schedule 4 (Restricted drugs)

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21
Q

Methoxyflurane: Adult Doses

A

3 mL
Repeated once after 20 minutes
Total max. dose = 6 mL

22
Q

Methoxyflurane: Paediatric Doses

A

3 mL

Single dose only

23
Q

Deep sedation has been identified with methoxyflurane administration in Pts < 5 years. T/F?

A

True

24
Q

Methoxyflurane: Total weekly dose should not exceed:

A

15 mL

Administration on consecutive days not recommended

25
Q

Paracetamol: Drug Class

A

Analgesic

Antipyretic

26
Q

Paracetamol: Pharmacology

A

Aminophenol derivative
Exhibits analgesic and antipyretic properties
No significant anti-inflammatory activity

27
Q

Paracetamol: Metabolism

A

By the liver

Excreted by kidneys

28
Q

Paracetamol: Indications

A

Mild to moderate pain

Fever (causing distress)

29
Q

Paracetamol: Contraindications

A

Allergy/adverse drug reaction

Pts < 1 month old

30
Q

Paracetamol: Precautions

A
Hepatic dysfunction 
Soluble tablets (sodium restriction)
31
Q

Paracetamol: Side Effects

A

Nausea

32
Q

Paracetamol: Presentation

A

Tablet: 500 mg
Elixir: 120 mg / 5 mL
Soluble tablet: 250 mg

33
Q

Paracetamol: Onset and Duration

A

Onset @ 10 - 60 minutes

Duration @ 4 hours

34
Q

Paracetamol: Schedule

A

Schedule 2 (therapeutic poisons)

35
Q

Paracetamol: Route

A

PO = per oral

36
Q

Paracetamol: Adult Dosage

A

Mild to moderate pain
Fever (causing distress).

> 16 years old: 0.5 g - 1 g
Presentation: tablet
Repeated every 4 hours
Total max dose in 24 hours: 4 g

37
Q

Paracetamol: Paediatric Dosage

A

Mild to moderate pain
Fever (causing distress).

> 1 month old: 15 mg/kg
Presentation: elixir
Single dose only

> 7 years old: 15 mg/kg
Presentation: soluble tablet
Single dose only

38
Q

Ibuprofen: Drug Class

A

NSAID: Non-steroidal anti-inflammatory drug

39
Q

Ibuprofen: Pharmacology

A

Non-selective NSAID
Inhibits synthesis of prostaglandins
Provides an analgesic, antipyretic, and anti-inflammatory response

40
Q

Ibuprofen: Metabolism

A

Metabolised by the liver

Excreted by the kidneys

41
Q

Ibuprofen: Indications

A

Moderate pain due to acute inflammation and tissue injury

42
Q

Ibuprofen: Contraindicationa

A
Allergy/adverse drug reaction to any NSAID or aspirin
Current GI bleeding/peptic ulcers
Dehydration or hypovolaemia 
Renal impairment
NSAID-induced asthma
Heart failure
Pregnancy
Angiotension converting enzyme (ACE) inhibitors
Angiotensin II receptor blocker (ARBs)
Pt < 13 years old
Pt > 65 years old
Coagulant medications 
Diuretic treatment
43
Q

Ibuprofen: Precautions

A

Asthma
Hepatic dysfunction
History of GI bleeding/peptic ulcers

44
Q

Ibuprofen: Side Effects

A

Nausea
Dyspepsia
GI bleeding
Dizziness

45
Q

Ibuprofen: Presentation

A

Tablet, 200 mg

46
Q

Ibuprofen: Onset and Duration

A

Onset @ 15 minutes

Duration @ 4 - 6 hours

47
Q

Ibuprofen: Schedule

A

Schedule 2 (therapeutic poisons)

48
Q

Ibuprofen: Route

A

PO = per oral

49
Q

Ibuprofen may be used in conjuction with:

A

Paracetamol

50
Q

Ibuprofen: Adult Doses

A

Moderate pain due to acute inflammation and tissue injury
Tablet per oral (200 - 400mg)

Must not be administered within 6 hours of previous ibuprofen administration

51
Q

Ibuprofen: Paediatric Doses

A

QAS are not authorised to administer ibuprofen to paediatric Pts