Q5: Hormones + blood glucose, insulin, gluconeogenesis Flashcards

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1
Q

The regulation of blood glucose

is an example of

A

how different hormones interact in achieving homeostasis

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2
Q

Where are hormones produced?

A

glands

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3
Q

Glands that secrete hormones directly into the blood

A

endocrine glands

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4
Q

How are hormones carried?

A

in the blood plasma

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5
Q

Target cells of hormones

A

cells on which they act which have specific receptors on their cell-surface membranes that are complementary to a specific hormone

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6
Q

Hormones length of effect

A

can be effective in very low concentrations

but often have long-lasting and widespread effects

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7
Q

Second messenger model

A

mechanism of hormone action in regulation of blood glucose involving adrenaline and glucagon

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8
Q

Pancreas

A

large, pale gland which is situated in the upper abdomen, behind the stomach.

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9
Q

Islets of Langerhans

A

Hormone producing cells

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10
Q

Pancreas is made up of

A

cells that produces its digestive enzymes

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11
Q

Islets of Langerhans cells

2

A

alpha cells

beta cells

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12
Q

Alpha islets of Langerhans cells

A

larger and produce glucagon

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13
Q

Beta islets of Langerhans cells

A

smaller and produce insulin

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14
Q

Liver made up of

A

cells called hepatocytes

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15
Q

Where are hormones such as insulin and glucagon produced?

and where do they have their effects?

A

produced in the pancreas

effects in the liver

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16
Q

Glycogenesis

A

conversion of glucose into glycogen

17
Q

Glycogenolysis

A

breakdown of glycogen into glucose

18
Q

Gluconeogenesis

MUST KNOW FOR EXAM!

A

production of glucose from sources other than carbohydrate

19
Q

When the liver supply of glycogen is exhausted but blood glucose concentrations need to increase what happens?

A

gluconeogenesis

20
Q

What can the liver produce glucose from other than carbohydrates during gluconeogenesis

A

non-carbohydrates sources such as glycerol and amino acids

21
Q

Glucose is a substrate for…

A

respiration

22
Q

What happens if glucose concentration falls too low?

A

cells will be deprived of energy and die

23
Q

What happens if glucose concentration rises too high?

A

lowers the water potential of the blood and creates osmotic problems which can cause dehydration and be dangerous

24
Q

Homeostatic control of blood glucose is…

A

essential

25
Q

Normal blood glucose concentration

A

5 mmoldm-3

26
Q

Blood glucose comes from three sources

A
  1. directly from the diet
  2. glycogenolysis
  3. gluconeogenesis
27
Q

Which hormones operate to maintain a constant blood glucose concentration?
3

A

insulin
glucagon
adrenaline

28
Q

What type of protein is insulin?

A

globular

29
Q

If the beta cells of the islets of Langerhans in the pancreas’s receptors detect a rise in blood glucose concentration what happens?

A

they secrete insulin directly into the blood plasma

30
Q

Almost all body cells have glycoprotein receptors on their CSM’s that…

A

bind specifically with insulin molecules