Q1S2 Flashcards
Chromosomes can be classified based on:
A. Number of chromosomes
B. Position of centromeres
C. Based on arms ratio
D. All of the choices
D
Which of the following is NOT TRUE regarding the centromere?
A. Primary constriction where sister chromatids are linked
B. Consists of several hundred kilobases of repetitive DNA
C. Prevents abnormal end-to-end fusion of chromosomes
D. Responsible for chromosome movement at cell division
C
Which of the following is a correct classification of chromosomes based on the number of centromeres?
A. Monocentric
B. Metacentric
C. Submetacentric
A
Morphologically, the following chromosome: Y
A. Metacentric
B. Submetacentric
C. Acrocentric
D. Subtelometric
C
Select all that is true of telomeres
A. Present only in nonlinear DNAs of eukaryotes
B. Passed through the matrilineal line
C. Anchors chromosomes to nuclear walls in meiosis
D. Shortens over time with age
C, D
___ is a structure that structure that occurs when a chromosomes breaks in two places and its broken ends fuse together
Ring
L-S ratio:
P arm length is 1; Q arm length is 1
Metacentric
L-S ratio:
P arm length is 0.5, Q arm length is 1.5
Submetacentric
L-S ratio:
P arm length is 0.2, Q arm length is 1.2
Subtelocentric
The ___ structure of chromatin is a model for the structure of the 30 nm fibre. It is a secondary chromatin structure which helps to package DNA into the nucleus
Solenoid
In cytogenetics, the naming of chromosomal aberrations such follows notations like 22q11.2 which represents the disease DiGeorge Syndrome. The one one point two notation part is made possible by ___ of the transcriptionally active regions of the chromosome known as bands, sub bands, or sub sub bands
Staining
