Q I got wrong or things I forget

Question 1

What diseases does virulence factor K capsule of E.coli and how does it help the bacteria?

Answer 1

pneumonia and neonatal meningitis

helps it not be eaten by macrophages

Question 2

What drug do you give for gout that clears uric acid that is already made?

Answer 2

Rasburicase

-helps get rid of uric acid crystals already formed

Question 3

Ppl with Bulimia have what elevated in labs?

Answer 3

Amylase

-they also get Parotid gland hypertrophy

Question 4

What valve is affected in Carcinoid syndrome? and what happens to the heart?

Answer 4

Tricuspid valve

fibrotic endocardial thickening of Right heart

Question 5

What is Lanugo and where is it seen?

Answer 5

fine whispy body hair

anorexia

Question 6

Drug used to treat Chronic Gout?

Answer 6

Probenicid

Question 7

Stage of sleep affected when the person complains of not feeling rested after sleeping?

Answer 7

NREM stage 3

-delta slow wave

Question 8

Mismatch repair genes associated with what defect ?

Answer 8

Microsatelitte instability

-HNPCC (Lynch Syndrome)

Question 9

I-cell disease defect happens where?

Answer 9

Golgi

Question 10

What drug do you give to treat tumor lysis syndrome related gout stones?

Answer 10

Allopurinol

-it is good at PREVENTING uric acid formation, doesnt do much to the stones already made

Alternative is Febuxostat

Question 11

Mutation that happens to tumor suppressor genes?

ex. APC and KRAS

Answer 11

Gene Deletion

or

Loss of Function

Question 12

Bone disease associated with Primary Hyperparathyroidism?

Answer 12

Osteitis fibrosa cystica

• “brown tumor” made of osteoclasts and hemosiderin
• they have Hypercalcemia so they get those symptoms

Question 13

What is Hawthorne effect?

Answer 13

ppl act differently when they know they are being watched

Question 14

Western blot analyzes ?

Answer 14

Protein (antigen) or antibody

Question 15

If there is a lesion in the midbrain above the red nucleus what posture do you see?

Answer 15

Decorticate

-arms bent, everything flexed

Question 16

What is Russell’s sign and what disease is it seen in?

Answer 16

scarring on the knuckles from inducing vomitting

Bulimia

Question 17

Conn Syndrome is ?

Answer 17

Primary Hyperaldosteronism

• high Na+ low K+
• low renin b/s RAAS will get supressed from HTN caused by retaining all the sodium

Question 18

Alpha motor neuron innervates ?

Answer 18

Extrafusal fibers

Question 19

When you get HIT w/ Heparin switch to ?

Answer 19

Bivalirudin or Agatroban

Question 20

How is progesterone in menstrual irregularities?

Answer 20

Low

Question 21

What are the 3 Macrolides ?

Answer 21

Clarithromycin

Azithromycin

Erythromycin

Question 22

MOA:

Phenylepherine

Answer 22

Question 23

P450 inhibitors ?

“pick egs”

Answer 23

Protease (-)

Isoniazid

Cimetidine

Ketoconazole

Erythromycin

Grapefruit juice

Sulfonamides

Question 24

How to treat chlamydia ?

Answer 24

Azithromycin or Doxycycline

+

Ceftriaxzone for gonorrhea

Question 25

Drugs that cause Torsade de pointes ?

(6)

Answer 25

Class 1 antiarrythmics (A & C)

Class 3 antiarrythmics

Macrolides

Haloparidol

TCA

Ondansentron

Question 26

What is Lymphogranuloma Venerum ?

Answer 26

Stage 2 Syphillis

painful lymphadenopathy

Question 27

MOA:

Clonidine

Answer 27

a 2 agonist

Question 28

MOA:

Dobutamine

Answer 28

ß1 agonist

Question 29

Isoproterenol

MOA?

Answer 29

ß1 agonist

Question 30

MOA:

Terbutaline

Answer 30

ß2 agonist

Question 31

MOA:

Mirtazapine

Answer 31

alpha 2 antagonist

Question 32

MOA:

a-methldopa

Answer 32

alpha 2 agonist

Question 33

MOA:

Phentolamine & Phenoxybenzamine

Answer 33

Question 34

Answer 34

Question 35

MOA:

Prazosin

Answer 35

alpha 1 antagonist

Question 36

What type of Hernias present young, before 30 y.o ?

Answer 36

Indirect Hernia