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Cellebio > Purinsyntese > Flashcards

Purinsyntese Flashcards

1
Q

Hvilke enzymer regulerer purinsyntesen?

A

PRPP syntetase, glutamin:fosforibosyl pyrofosfat amidotransferase,

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2
Q

PRPP syntetase. Funksjon og regulering?

A

Funksjon: katalyserer ribose 5- fosfat + ATP —> PRPP

Aktivator: Pi
Hemmer: Purin ribonukleotid

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3
Q

Glutamin: fosforibosyl pyrofosfat amidotransferase. Funksjon og regulering?

A

Funksjon: katalyserer PRPP + glutamin + H2O —> 5’ fosforibosylamin

Amidgruppen på glutamin byttes ut med fosfatgruppen på C-1 til PRPP.

Hemmer: ATP, GMP, IMP
Aktivator: PRPP

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Cellebio (13 decks)

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