Pupils Flashcards

1
Q

What is internuclear ophthalmoplegia and what causes it?

A

Disorder of the MLF

Caused by MS in younger people and stroke in older people

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2
Q

What is the symptom of internuclear ophthalmoplegia?

A

Horizontal diplopia

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3
Q

What is seen when observing the eye movements of someone with internuclear ophthalmoplegia?

A

Affected eye: cannot adduct

Contralateral eye: nystagmus on abduction

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4
Q

What is the name for unequal pupils?

A

anisocoria

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5
Q

What is the name for dilated and constricted pupils?

A

Dilated: mydriatic
Constricted: miotic

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6
Q

State some causes of unilateral dilated pupils

A
  • CN3 palsy
  • Holmes-Adie
  • Dilating agents e.g. atropine
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7
Q

State some causes of unilateral constricted pupils

A
  • Horner’s
  • Uveitis
  • Argyll Robertson
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8
Q

What is an RAPD?

A

Inability to react to light due to pathology of optic nerve or retina

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9
Q

What conditions can cause an RAPD?

A
  • Optic neuritis: MS
  • Optic nerve atrophy
  • Vasculidities
  • Acute closed angle glaucoma
  • Thyroid eye disease compressing the nerve
  • Retinal detachment
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10
Q

What nerves form the afferent and efferent pathway of the pupillary light reflex?

A

afferent: optic nerve and retina
efferent: parasympathetics on CN3

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11
Q

What can cause bilaterally fixed dilated pupils?

A

Diffuse intracranial pathology causing brainstem herniation and brain death

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12
Q

What can cause bilaterally fixed small pupils?

A

Pontine haemorrhage

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13
Q

What nerves form the afferent and efferent pathway of the accommodation reflex? What is the result of these being activated?

A

afferent: optic
efferent: oculomotor

  • pupil constriction
  • eye conversion (medial rectus)
  • lens convex
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14
Q

What is light near dissociation? What can cause it?

A

The pupil will react to accommodation but not to light

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15
Q

What is Holme’s Adie? What is found on neurological examination?

A

A benign condition affecting females in their 40’s. It is due to damaged post-ganglionic parasympathetics or damage to the ciliary ganglion

  • reduced knee reflexes
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16
Q

What is Argyll Robertson?

A

Highly specific for neurosyphilis with damage to the midbrain
Bilaterally constricted pupils with light near dissociation

17
Q

Compare the response on Holmes Adie and Argyll Robertson to topical miotic/ dilating agents

A

Holmes Adie responds well to constricting agents

Argyll Robertson does not respond to dilating agents

18
Q

What are midbrain pupils and what can cause them?

A

Fixed mid-dilated pupils due to midbrain lesion eg MS or basilar artery stroke

19
Q

Compare the pupil in uveitis and acute glaucoma

A

Uveitis: fixed, oval and small

Acute glaucoma: fixed, oval, mid-dilated