Pulp Lecture Flashcards

1
Q

Name the four layers from inside to outside

A
  1. pulp core 2. Cell dense zone 3. Cell free zone of weil, 4. odontoblast layer
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2
Q

What type of collagen most makes up the pulp ECM?

A

Collagen III (and some Collagen I)

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3
Q

What are the 5 proteoglycans found in Pulp?

A
  1. Chondroitin-6-sulfate
  2. Chondroitin-4-sulfate
  3. Heparin sulfate
  4. Dermatan sulfate
  5. Keratin sulfate
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4
Q

What is different about the junctional complexes between odontoblasts?

A

They are adherens but not zonular.

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5
Q

Odontoblasts can form ___ junctions with___

A

gap, pulpal fibroblasts

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6
Q

What key growth factors are in the dentin matrix?

A

VEGF, TGFb1, BMP-2

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7
Q

What does an aged odontoblast look like?

A

Fewer organelles, less secretory activity, nucleus more central

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8
Q

How far does the odontoblast process reach?

A

Possibly all the way to the DEJ. Maybe only 1/3. Unknown.

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9
Q

What is the difference between reactionary dentin and reparative dentin?

A

Reactionary: mild stimulus. Reparative: strong stimulus.

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10
Q

Where are the dendritic cells found in the pulp?

A

In the odontoblast layer

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11
Q

___are closely associated with the neuronal and vascular components of the pulp

A

Dendritic cells

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12
Q

How many arterioles per root?

A

4-8.

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13
Q

Where does pulp blood come from?

A

Externa Carotid artery and superior/inferior alveolar arteries

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14
Q

What layer are the capillaries found in?

A

during primary dentin formation: odontoblast layer.

Thereafter: cell free zone

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15
Q

What makes up lymphatic vessels?

A

thinner walls, epithelial lining and smooth muscle layer

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16
Q

Nerve fiber branches in the coronal pulp form the

A

Plexus of Raschkow (absent in root pulp)

17
Q

What make up the nerve fibers?

A

Afferent nerves from trigeminal, (myelinated Ad and unmyelinated C axons) AND sympathetic branches from the superior cervical ganglion.

18
Q

More myelinated nerves are found nearer the

A

crown

19
Q

What are the three theories of dentin sensitivity?

A
  1. Direct innervation, 2. Odontoblast nociception, 3. Tubule fluid conductance (hydrodynamic)