Pulmonology Flashcards
What type of lung disease is assessed by FEV1 and FEV1/FVC ratio?
Obstructive
What is the diagnostic value of FEV1/FVC for obstructive lung disease?
< 0.7
Which type of lung disease has a concave scooping in the lung tracing in the latter half of expiration?
Obstructive
When is a bronchoprovocation challenge indicated?
Patient with initial normal spirometry testing
What are the the three factors that cause variation in the oxyhemoglobin dissociation curve?
Temperature
Acidosis (pH)
Phosphorus (2,3-DPG)
What is the treatment of methemoglobinemia?
100% O2
Methylene blue
What is the most common cause of stridor in the newborn?
Laryngomalacia
Which nerve is affected in vocal cord paralysis?
Recurrent laryngeal nerve
What genetic syndrome would you be worried about with the finding of laryngeal webs?
DiGeorge syndrome
What condition would you suspect in a newborn where trachea cannot be intubated even though larynx is visualized?
Tracheal agenesis
Which lobe is typically involved with lobar emphysema?
Left upper lobe
What is Scimitar Syndrome
Congenital Pulmonary Venolobar Syndrome
- Pulmonary venous blood from R lung returns to IVC
What type of shunt is Scimitar Syndrome?
L to R shunt
What is the most common cause of pulmonary arteriovenous malformations?
Hereditary hemorrhagic telangiectasia (HHT)
OR Osler Weber Rendu syndrome
What are the two classifications of pulmonary sequestrations?
Intralobar and extralobar
Are intralobar pulmonary sequestrations typically in the upper or lower lobes of the lungs?
Lower lobes
Are extralobar pulmonary sequestrations on the R or L side typically?
L side
What is the treatment of choice of pulmonary sequestrations?
Surgical removal
What are the most common cysts in infancy?
Bronchogenic cysts
Are bronchgenic cysts moreso on the right or left?
Right
Single, unilocular
What is the management of bronchogenic cysts?
Surgical removal
What is eventration?
Marked elevation of the diaphragm
What is the main virus responsible for croup?
Parainfluenza
How long does racemic epi last?
~ 2 hours
Virus most commonly causing bronchiolitis
RSV
Which patients require the RSV vaccine (Synagis)?
Children < 2 y/o with chronic lung disease or congenital heart disease or infants < 29 weeks gestation in 1st winter
T/F: Synagis should be discontinued if a patient receiving it acquires RSV
True
In what setting are blood cultures recommended for pneumonia?
Inpatient, for severe pneumonia
What are the values of pH, glucose, pleural fluid:serum glucose ratio & LDH that would be concerning for empyema?
pH < 7.30
glucose < 40
PF:SG ratio < 0.5
LDH > 1000
What are the most common complications from S. pyogenes pneumonia?
Abscesses and empyema
Which two bacteria should you be concerned about fora pneumonia with evidence of pneumatoceles on CXR?
S. pyogenes
S. aureus
What is the definitive diagnosis of Mycoplasma pneumoniae?
IgM antibody
Possible cold agglutinin titer
What is the treatment of histoplasmosis if persistent localized disease?
Itraconazole
What is the treatment of disseminated histoplasmosis?
Amphotericin B
Which fungus has a sputum sample showing a large, single, broad-based budding yeast?
Blastomycosis
What is the treatment of indolent blastomycosis? Disseminated?
Indolent- Itraconazole
Disseminated- Amphotericin B
What fungal infection should you expect in patient with asthma, with worsening symptoms and brown mucous plugs w/ peripheral eosinphilia?
ABPA
What is the treatment of ABPA?
Itraconazole
Steroids
Gram positive diplococci seen in sputum sample w/ large number of PMNs and few epithelial cells most likely indicates which organism?
Strep pneumo
What are the extrapulmonary manifestations of Mycoplasma pneumonia?
Hemolytic anemia, splenomegaly, erythema multiforme, arthritis, pharyngitis, confusion
What is the mechanism of action of Omalizumab?
Blocks IgE receptors
What viral illness particularly puts kids at risk for Bronchiolitis Obliterans
Adenovirus
How is bronchiolitis obliterans diagnosed?
Lung biopsy
What is the gold standard for diagnosis of bronchiectasis?
HRCT- high resolution CT
T/F: Prematurity is a risk factor for SIDS
True
Are boys or girls more commonly affected by SIDS?
Boys
What are the sodium and chloride concentrations in a CF patient’s sweat?
> 60 meq/L