Pulmonology Flashcards
confirms diagnosis of asthma
Spirometry
First line tx for BA
Inhaled Corticosteroid
Pathophysio of BA
Airway hyperresponsiveness
Chronic cugh
> 8 weeks
M/C chroic cough, non smoker, normal XRay
Post Nasal Drip
Asthma
GERD
Major risk factor for asthma
Atopy
M/C Allergens to trigger Asthma
Dermatophagoides
Worse art Night
Bronchial Asthma
Quantify expiratory airway obstruction
Simple spirometry
Determines reactive airway disease
Metachollne/ Histamine
Criteria BA by spirometry
Reduced FEV1/FVC <0.7
Reduced FEV1 that inc by >12% and by at least 200 mg from baseline post bronchodilator
Reduced FEV1 that inc by >12% and by at least 200 mg from baseline 4 weeks after steroid trial
When to start ICS
> 2 symptoms/ month
1 waking for asthma/ month
Asthma symptoms + risk for exacerbations
When to step up ICS
Persistence 2-3 mos
When to step down
Maintained for 3 mos
Asthma relievers
SABA
SAMA
Metylxanthine
Asthma Controllers
Inhaled CS Systemic Steroids LABA Leukotriene modifying agents Cromolyn Anti Ige
Indication for impending O2 failure
Normal or rising CO2
Exercise Induced asthma
Leukotrienes/ Bronchodilators Prior
Older, Smoker, Barrel Chest, Expiratory wheezes
COPD
Best initial test for COPD
CXR
Best diagnostic test during acute exacerbation
ABG
Target Organ Saturation COPD
> 90%
Most common risk factor COPD
Tobacco Smoking
Hallmark COPD
Airflow obstruciton
Confirms airway limitation in COPD
FEV1/FVC <0.7
COPD Manif
Dyspnea Chronic cough Chronic sputum Barrel Chest Quiet Chest Hyperresonance Tripod position Right Sided Heart Failure - Cor pulmonale
Definitive COPD diagnostic
FEV1/FVC <0.7
GOLD 1
> 80
GOLD 2
> 50-<80
GOLD 3
> 30-<50
GOLD 4
<30
Dyspnea Rating
0 not troubled 1 level ground slight hill 2 slower similar age 3 100 m 4 leave the house
3 interventions COPD
Smoking cessation
O2 therapy
Lung volume reduction
When to start supplemental O2 in COPD
pO2 <55/ sat <88
pO2 <60/ sat <90
For moderate to severe exacerbations
Roflumilast
5As to quit smoking
Ask Advice Assess Assist Arrange
COPD Exacerbation
Dyspnea
Cough
Change in Sputum
Bacteria in COPD exacebration
S. pneumoniae
H. influenzae
M. catarrhalis
Non Invasive Positive Pressure Ventilation
Respiratory acidosis
Severe dyspnea
Persistent hypoxemia
Antibiotics given in COPD
Azithromycin
Adequate sputum sample
> 25 neutrophils
< 10 squamous EC
Urinary Antigen for CAP
Pneumococcal and Legionella
CURB 65
Confusion Urea/ BUN >30 RR >30 BP >90/<60 65 yo
Low Risk CAP Tx
Amoxixcillin - no co morbids
Co Amox - stable co morbids
Moderate Risk
Ampi Sul/ Ceftri + Levoflox/ Moxiflox (same with high Risk)
High Risk with Risk for Pseudomonas
Pip Taz + Genta/ Amika
Resolution Time
1 week Fever
4 weeks Sputum
6 weeks Cough
6 mos normal
Normal XRay 4-12 weeks
Leukocytosis 2-4 days
Most accurate test CAP
Chest CT
DOC Lung Abscess
Clindamycin
CD4 <200
Pneumocytsis Pneumonia
Gold Standard for Pneumocystis Pneumonia
Bronchial Alveolar Lavage
DOC Pneumocystis Pneumnia
TMP/SMX
Best initial test PTB
XRay + Sputum AFB