Pulmonology Flashcards

1
Q

opacification, consolidation, air bronchograms on CXR

A

pneumonia***?

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2
Q

hyperlucent lung fields with flattened diaphragms

A

COPD emphysema

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3
Q

heart > 50% AP diameter, cephalization, Kerly B lines, interstitial edema

A

CHF***?

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4
Q

cavity containing air-fluid level on CXR

A

lung abscess***?

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5
Q

upper lobe cavitation, consolidation, +/- hilar adenopathy

A

pancoast tumor***?

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6
Q

thickened peritracheal stripe and splayed carina bifurcation on CXR

A

???

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7
Q

Pleural effusions see…

A

> 1 cm fluid on lateral decubitus

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8
Q

Px pleural effusion

A

thoracentesis

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9
Q

Transudative pleural effusion ddx

A
CHF
nephrotic
cirrhotic
RA 
TB
Malignant
PE
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10
Q

Low pleural glucose on thoracentesis, think

A

RA

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11
Q

High lymphocytes in pleural fluid from thoracentesis, think

A

TB

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12
Q

Bloody pleural fluid from thoracentesis, think

A

Malignant
OR
PE

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13
Q

Exudative pleural effusion ddx

A

parapneumonic
malignancy
etc.

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14
Q

Complicated pleural effusion from thoracentesis… signs and tx

A

+ gram stain OR culture
pH < 7.2
glucose <60

tx: insert chest tube for drainage

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15
Q

Light’s criteria: transudative if…

A

LDH < 200
LDH eff/serum < 0.6
Protien eff/serum < 0.5

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16
Q

PE risks

A
s/p surgery
long car ride/plane ride
hypercoagulable state (cancer, nephrotic)
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17
Q

PE sx

A
tachycardia
tachypnea
decr pO2
pleuritic cp
hemoptysis
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18
Q

PE signs

A
right heart strain on ECG
sinus tachy
decr vascular markings on CXR
wedge infarct
ABG with low CO2 and O2
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19
Q

If suspect PE, first give…then

A

heparin

THEN
work up with V/Q scan then spiral CT

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20
Q

Gold standard PE

A

pulmonary angiography

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21
Q

PE tx

A

heparin warfarin overlap
thrombolytics if severe, but NOT if s/p surgery or hemorrhagic stroke
if life threatening: surgical thrombectomy
IVC filter if contraind to chronic coagulation

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22
Q

ARDS pathophys

A

inflammation –> impaired gas exchange –> inflammation mediator release –> hypoxemia

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23
Q

ARDS etiology

A
sepsis
gastric aspiration
trauma
low perfusion
pancreatitis
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24
Q

ARDS dx

A
  1. PaO2/FiO2 < 200
    ( < 300 means acute lung injury)
  2. Bilateral alveolar infiltrates on CXR
  3. PCWP is < 18 (means pul edema is non cardiogenic)
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25
ARDS tx
mechanical ventilation with PEEP
26
FEV1/FVC < 80% predicted
obstructive
27
Improves > 12% with bronchodilator
asthma
28
Obstructive lung dz
asthma chronic bronchitis emphysema
29
Restrictive lung dz
Interstitial lung dz (sarcoid, silicosis, asbestosis) | Structural (super obese/pickwickian, MG/ALS, phrenic nerve paralysis, scoliosis
30
Obstructive PFTs
``` FVC decr FEV1 more decr FEV1/FVC < 80% TLC incr >120% RV incr >120% ```
31
DLCO reduced in obstructive lung dz
emphysema 2/2 alveolar destruction
32
Restrictive PFTs
``` FVC decr FEV1 decr FEV1/FVC normal TLC decr RV decr Does not improve with bronchodilator ```
33
DLCO reduced in restrictive lung dz
ILD due to fibrosis thickening distance
34
COPD chronic bronchitis criteria dx
productiev cough > 3 mo for 2 y
35
Chronic bronchitis tx
1st line: ipratropium, tiotropium 2nd line: beta agonists 3rd line: theophylline
36
COPD indications to start O2
PaO2 < 55 SpO2 < 88% or if cor pulmonale, < 59
37
Criteria for COPD exacerbation
change in sputum | increasing dyspnea
38
Tx for COPD exacerbation
1. quit smoking | 2. cont O2 tx > 18 h/day
39
Why is goal SpO2 94-95% instead of 100%?
COPDers are chronic CO2 retainers, hypoxia is the only drive for respiration, so if relieve hypoxia, lose oxygen drive completely
40
Important vaccinations for COPD
pneumococcus w/ 5 y booster yearly influenza
41
Your COPD patient comes with a 6 week history of clubbing... dx, next step, underlying cause
hypertrophic osteoarthropathy get CXR most likely cause is underlying lung malignancy
42
asthma: if pt has sxs twice a week and PFTs are normal
albuterol only
43
asthma: if pt has sxs 4x a week, night cough 2x a month, and nL PFTs
albuterol + ICS
44
asthma: if pt has sxs daily, night cough 2x a week, and FEV1 is 60-80%
albuterol + ICS + salmeterol
45
asthma: pt has sxs daily, night cough 4x a week, and FEV1 is < 60%
albuterol + ICS + salmeterol + montelukast + oral steroids
46
Asthma exacerbation tx
albuterol neb PO/IV steroids watch peak blow rates and blood gas PCo2 should be low
47
Normalizing PCO2 in asthma exacerbation means ...
impeding respiratory failure | INTUBATE
48
Asthma exacerbation complications
allergic bronchopulmonary aspergillus
49
1 cm lung nodules in upper lobes w/ eggshell calcifications
silicosis get yearly TB test! give INH for 9 mo if > 1 cm
50
reticulonodular process in lower lobes with pleural plaques
asbestosis MC cancer is bronchogenic carcinoma but incr risk for mesothelioma
51
patchy lower lobe infiltrates, thermophilic actinomyces
hypersensitivity pneumonitis "farmer's lung"
52
hilar lymphadenopathy, incr ACE, erythema nodosum
sarcoidosis
53
hilar lymphadenopathy, incr ACE, erythema nodosum with hypercalcemia
2/2 incr mphages making vit D
54
important referral in sarcoidosis dx/tx
ophthalmology --> uveitis conjunctivitis in 25%
55
sarcoidosis dx/tx
dx with biopsy | tx with steroids
56
So you found a pulmonary nodule...1st step
look for an old CXR to compare!
57
Characteristics of benign lung nodules
- popcorn calcification (hamartoma) - concentric calcification (old granuloma) - pt < 40 yo - < 3 cm, well circumscribed
58
Characteristics malignant lung nodules
- RF: smoker, old - > 3 cm - eccentric calcification
59
Tx malignant lung nodules
open lung bx | remove nodule
60
A patient presents with weight loss, cough, dyspnea, hemoptysis, repeated pnia or lung collapse...think
lung cancer
61
MC cancer in non-smokers
adenocarcinoma occurs in scars of old pneumonia
62
lung adenocarcinoma location and mets
peripheral cancer | mets to liver, bone, brain, and adrenals
63
lung adenocarcinoma effusion characteristics
exudative with high hyaluronidase
64
pt with kidney stones, constipation, malaise, low PTH, and central lung mass
squamous cell carcinoma paraneoplastic syndrome 2/2 secretion of PTH-rP low PO4 high Ca2+
65
pt with shoulder pain, ptosis, constricted pupil, and facial edema in setting concerned for lung cancer
Superior sulcus syndrome 2/2 small cell carcinoma central cancer also
66
pt with ptosis better after 1 minute of upward gaze
Lambert Eaton Syndrome 2/2 small cell carcinoma antibody to pre-synaptic Ca2+ channel
67
old smoker presenting with Na+ 125, moist mucus membranes, no JVD?
SIADH 2/2 small cell carcinoma produces euvolemic hyponatremia
68
tx SIADH
fluid restriction | +/- hypertonic (3%) saline in < 112
69
CXR showing peripheral cavitation and CT showing distant mets (setting suspected lung cancer)
large cell carcinoma