Pulmonary Venous Thromboembolism Flashcards

1
Q

What is the most common type of emboli?

A

Thromboembolism

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2
Q

What is Virchow’s Triad?

A

Venous Stasis
Vessel Injury
Hypercoagulability

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3
Q

What are the Inherited risk factors for a Pulmonary Embolism?

A

Factor V Leiden
Prothrombin Gene Mutation

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4
Q

What are the Provoking (Acquired) risk factors for a Pulmonary Embolism?

A

Recent Surgery
Trauma
Immobilization
Hormone Therapy
Active Cancer

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5
Q

What are the Non-Provoking (Acquired) risk factors for a Pulmonary Embolism?

A

Obesity
Heavy Cigarette Smoking

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6
Q

Where do most emboli arise from before becoming a pulmonary embolism?

A

Lower Proximal Veins
- Iliac
- Femoral
- Popliteal

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7
Q

What is most commonly used to quantify clinical risk assessment and calculate probability of a pulmonary embolism?

A

Wells Score

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8
Q

Wells Score

A

Leg Swelling + Pain with Palpation of Deep Veins - 3.0
Alternative Diagnosis is less likely than PE - 3.0
Heart Rate > 100 - 1.5
Immobilization for 3 days or surgery in last 4 weeks - 1.5
Previous PE or DVT - 1.5
Hemoptysis - 1.0
Cancer - 1.0

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9
Q

May be used to identify patients for whom no further testing is indicated.

A

Pulmonary Embolism Rule-out Criteria
(PERC)

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10
Q

PERC Score

A

Age 50+
HR 100+
O₂ Sat. < 95%
Unilateral Leg Swelling
Hemoptysis
Recent Surgery or Truma
Prior PE or DVT
Hormone Use

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11
Q

PERC Rule if No Criteria are met.

A

No further work-up

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12
Q

PERC Rule if 1 Criteria met.

A

D-Dimer

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13
Q

What to do with positive D-Dimer?

A

CT PE

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14
Q

What is the diagnostic test of choice for a pulmonary embolism?

A

CT PE

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15
Q

EKG findings of a patient with a Pulmonary Embolism

A

S1Q3T3

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16
Q

Chest X-Ray findings of a patient with a Pulmonary Embolism

A

Wedge-Shaped Infiltrate

17
Q

Profound hypoxia with a normal Chest X-Ray is highly suspicious of?

A

Pulmonary Embolism

18
Q

What is the first line imaging used for a Pulmonary Embolism?

19
Q

What can be used in patients who you suspect have a PE but have an intolerance to contrast?

20
Q

High Risk or Massive PE

A

Hemodynamically Unstable
- BP < 90 or drops by > 40mmHG below baseline for 15 minutes.
- HR < 40
- Pulselessness

21
Q

Acute PE without systemic hypotension BUT with either Right Ventricular Dysfunction or Myocardial Necrosis.

A

Submassive or Intermediate PE

22
Q

What type of PE is associated with the highest mortality.

A

In Transit through the Heart

23
Q

Where do most PEs move to?

A

Lobar, Segmental, and Subsegmental Branches of Pulmonary Artery

24
Q

What should you start immediately in a patient with a PE?

A

Heparin drip

25
What is the first line medication to transition to after a Heparin drip has been started in a patient with a pulmonary embolism?
DOAC - rivaroxaban - apixaban
26
How long must Anticoagulation be administered for following a PE?
At least 3 months