Pulmonary Neoplasms

Question 1

_____ density is more suspicious for malignancy

Answer 1

Solid

(vs. ground glass)

Question 2

Mass vs nodule

Answer 2

>3cm = Mass

(smaller than that is nodule)

Question 3

Smal cell carcinoma is not a ______

Answer 3

surgically resectable tumor

Question 4

______ increases risk 20X

Answer 4

1 PPD for 40 years

Question 5

In addition to packs per day, ____ is another risk factor

Answer 5

Airway obstruction

Question 6

Passive smoking: avg lifetime exposure (via spouse) increases risk by _____

Answer 6

2-3 times

Question 7

Gender difference of risk

Answer 7

Women = 1.2 to 1.7 fold higher risk than men.

Question 8

Amospheric pollution compounds

Answer 8

1. 3,4 benzpyrene
2. Arsenous Oxide
3. Nickel
4. Chromium compounds
5. Non-combustible aliphatic hydrocarbons
6. Chloromethyl ethers

Question 9

Occupational factors that increase risk

Answer 9

1. Radioactive materials
2. Asbestos
3. Chromates
4. Mustard gas
5. Hematite
6. Iron/silica
7. Radon-gaseous decay

Question 10

Increased genetic risk:

Answer 10

Loss of DNA sequences in short arm of chromosome 3 or 11

(3p or 11p)

Question 11

Non-small cell carcinoma

Answer 11

• Squamous cell carcinoma
• Adenocarcinoma
• Large-cell carccinoma
• Adenosquamous carcinoma

(also acinar/papillary adeno, Giant cell/clear cell carcinoma)

Question 12

Small cell carcinomas

Answer 12

Oat cell carcinoma

Intermediate cell type

Combined Oat cell carcinoma

Question 13

Other Types of LCs

Answer 13

1. Carcinoid
2. Bronchial gland carcinoma
   
   1. (adenoid cysticcarcinoma, mucoepidermoid carcinoma)
3. Hamartoma
4. Lymphoma
5. Met’ Cancer

Question 14

Chronic interstitiaal pneumonitis and scleroderma patients can develop

Answer 14

“scar carcinoma”